Results 71 to 80 of about 77,886 (252)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Does self-efficacy of teachers toward inclusive education differ between primary and secondary school? A cross-cultural study of Ghana and the United Arab Emirates

Social Sciences and Humanities Open
There are ongoing debates on the level of education that students with special educational needs could participate in and enjoy as part of their fundamental right to education.
Ahmed Mohamed, Maxwell Peprah Opoku, Bernadette M. Guirguis, Ebenezer Mensah Gyimah, Maya Al Yafi, Shouq Alqahtani, Safa Alharthi, Mahra Aldhanhani, Al Zahra Aljaberi   +8 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

The Mediating Role of Satisfying Basic Psychological Needs on The Relationship Between Parenting Styles and Mental Health in Gifted Students

آموزش بهداشت و ارتقاء سلامت ایران, 2017
Background and Objective: Living up based on authentic goals, meaning and striving to achieve personal growth have been defined as mental health. Many studies have addressed the effect of personal and contextual factors on the mental health.
Somayeh Sadati Firoozabadi, Ghavam Moltafet   +1 more
doaj  

Matematik Öğretmenlerinin Üstün Zekâlılar Hakkındaki Görüşlerinin İncelenmesi: Bir Metafor Çalışması

Sakarya University Journal of Education, 2018
Metaforlar ile birzihinsel şema başka bir zihinsel şema altında açıklanmasına olanak sağlayangüçlü zihinsel yapılardır. Metaforlar yardımı ile bir kişinin herhangi bir konuhakkındaki görüş ve düşünceleri anlaşılabilir.
Mehmet Kırmızı, Kamuran Tarım
doaj   +1 more source

Delegates Discourse: Australia 2022 (World Gifted Newsletter)

, 2022
Australian state and territory gifted associations continue to promote the needs of gifted and talented children around Australia through implementing activities for gifted children, their parents, and teachers.
Thraves, Genevieve, Ronksley-Pavia, Michelle, Townend, Geraldine, Henderson, Lesley   +3 more
core  

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Perfectionism, Coping, and Underachievement in Gifted Adolescents: Avoidance vs. Approach Orientations

Education Sciences, 2016
Perfectionism can influence how one approaches challenges and deals with setbacks, and, consequently, can inhibit or facilitate achievement. The present study (1) explored the relationship between Frost’s six dimensions of perfectionism and five types of
Emily Mofield, Megan Parker Peters, Sumita Chakraborti-Ghosh   +2 more
doaj   +1 more source

Gifted and talented education: The English policy highway at a crossroads? [PDF]

, 2013
Copyright © 2013 by Sage Publications. This is the author's accepted manuscript. The final published article is available from the link below.In 1999, the British government launched an education program for gifted and talented pupils as part of its ...
Koshy, V
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source