Results 91 to 100 of about 239,682 (301)
Advanced Science, EarlyView.This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche +21 more
wiley +1 more source
Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier
Advanced Science, EarlyView.SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao +11 more
wiley +1 more source
Professional Development for Teachers of Gifted Education in Hong Kong: Instrument Validation and Training Effectiveness. [PDF]
Int J Environ Res Public Health, 2022 Cheung ACK +4 more
europepmc +1 more source
Advanced Science, EarlyView.Researchers have developed a patient‐derived organ‐on‐a‐chip model for pancreatic cancer by integrating cancer cells with supportive stromal and immune cells inside a microfluidic device. This system mimics the tumor microenvironment, enabling personalized testing of chemotherapy and immunotherapy, and offering new insights into how targeting ...
Darbaz Adnan +11 more
wiley +1 more source
Education for the gifted in Ecuador: analysis from the perspective of learning resources
Cogent EducationThis study analyzed the current state of education for gifted students in Ecuador using the Educational and Learning Capital Model (ELCM) to propose improvements in the development of programs and services.
Noemí Suárez Monzón +3 more
doaj +1 more source
Development and Evaluation of a Pioneer School-Based Gifted Education Program (Project GIFT) for Primary and Secondary Students in Hong Kong. [PDF]
Int J Environ Res Public Health, 2022 Shek DTL +4 more
europepmc +1 more source
Advanced Science, EarlyView.Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou +14 more
wiley +1 more source
Gifted Girls’ Learning Experience in General Education
Acta Paedagogica Vilnensia, 2019 The Munich Dynamic Ability-Achievement Model during the school period emphasizes the increasing impact of the school environment on the transformation of the ability (potential) of exceptional achievement, making it an integral part of the development of
Evelina Undro, Sigita Girdzijauskienė
doaj +1 more source
Doogie Howser, M.D., Ph.D., Ed.D.: The Myths and Realities of Gifted Students in Higher Education [PDF]
, 2001 This paper seeks to examine gifted student development, specifically regarding academic acceleration. The author will use published literature, observations from the field, and personal communication to: (a) characterize gifted students, (b) address the ...
Perez, Rosemary J.
core +1 more source
Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders
Advanced Science, EarlyView.In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang +22 more
wiley +1 more source