Results 101 to 110 of about 1,719 (204)

Liquid chromatography-Atmospheric pressure chemical ionisation/Mass spectrometry: a rapid and selective method for the quantitative determination of ginkgolides and bilobalide in ginkgo leaf extracts and phytopharmaceuticals

, 2002
In order to evaluate the composition of active constituents in phytopharmaceutical preparations, valid analytical methods are required. For the determination of the active terpene constituents of Ginkgo biloba (the ginkgolides and bilobalide), a liquid ...
Soldati, Fabio, Wolfender, Jean-Luc, Camponovo, Fabrizio, Hostettmann, Kurt, Jensen, Anette Gemal, Ndjoko Ioset, Karine   +5 more
core   +1 more source

Preparation of 7-substituted ginkgolide derivatives:potent platelet activating factor (PAF) receptor antagonists

, 2003
Ginkgolides are structurally unique constituents of Ginkgo biloba extracts and are known antagonists of the platelet-activating factor (PAF) receptor. Ginkgolide C is 25-fold less potent than ginkgolide B as a PAF receptor antagonist, due to the presence
Strømgaard, Kristian, Vogensen, Stine Byskov, Ishii, Satoshi, Shindou, Hideo, Nakanishi, Koji, Shimizu, Takao, Jaracz, Stanislav, Suehiro, Makiko   +7 more
core   +1 more source

Influence of lipophilicity and stereochemistry at the C-7 position on the cardioprotective and antioxidant effect of ginkgolides during rat heart ischemia and reperfusion

, 2005
The extent to which the cardioprotective effect of ginkgolides is related to their lipophilicity rather than to their anti-platelet activating factor (PAF) effect was addressed in isolated rat hearts submitted to ischemia and reperfusion.
Drieu, K., Culcasi, M., Carrupt, Pierre-Alain, Pietri, S., Billottet, L., Martel, Sophie   +5 more
core  

Preparation of 7-Substituted Ginkgolide Derivatives:  Potent Platelet Activating Factor (PAF) Receptor Antagonists

, 2016
Ginkgolides are structurally unique constituents of Ginkgo biloba extracts and are known antagonists of the platelet-activating factor (PAF) receptor. Ginkgolide C is 25-fold less potent than ginkgolide B as a PAF receptor antagonist, due to the presence
Kristian Strømgaard (412489), Stine Byskov Vogensen (3015327), Makiko Suehiro (3015336), Takao Shimizu (249458), Hideo Shindou (3015333), Satoshi Ishii (249457), Stanislav Jaracz (3015330), Koji Nakanishi (1650112)   +7 more
core   +1 more source

Adulteration Determining of Pharmaceutical Forms of Ginkgo biloba Extracts from Different International Manufacturers

, 2014
In this study, Ginkgo biloba products used for the same purpose, but licensed to varying authorities were analyzed in point of similarity to each other.
DEMİREZER, LÜTFİYE ÖMÜR, GÜVENALP, Zühal, Kuruuzum-Uz, Ayse, PALASKA, ERHAN, Buyukkaya, Asli, UÇAKTÜRK, EBRU   +5 more
core   +2 more sources

Molecular determinants of ginkgolide binding in the glycine receptor pore

, 2006
Ginkgolides are potent blockers of the glycine receptor Cl- channel (GlyR) pore. We sought to identify their binding sites by comparing the effects of ginkgolides A, B and C and bilobalide on alpha1, alpha2, alpha1beta and alpha2beta GlyRs.
Rebecca Hawthorne (20022531), Brett Cromer (11895804), Joseph Lynch (1863715), Michael Parker (131082), Hooi-Ling Ng (20021376)   +4 more
core  

Total synthesis of (.+-.)-ginkgolide B [PDF]

Journal of the American Chemical Society, 1988
E J, Corey, Myung-Chol, Kang, Manoj C, Desai, Arun K, Ghosh, Ioannis N, Houpis   +4 more
openaire   +2 more sources

Investigating the Therapeutic Mechanism of Ginkgo Biloba Extract in Alzheimer’s Disease via Integrated Network Pharmacology and Molecular Docking

Objective:This study aimed to investigate the mechanisms through which ginkgolides in Ginkgo biloba extract (GBE) may protect against Alzheimer’s disease (AD).Methods:Candidate ginkgolide constituents and their putative targets were identified using the ...
Liu YANG, Li WANG, Ruirui PENG, Li JIN, Fang WANG, Yipei LI, Juan GONG   +6 more
core   +1 more source

Functional identification of two cytochrome P450 enzymes involved in diterpenoid oxidation in <i>Ginkgo biloba</i>. [PDF]

Front Plant Sci
Chen L, Zhang Y, Fan Z, Wang Y, Li Y, Zhou Q, Lin GQ, Tang GL, Zhou Y, Wu S.   +9 more
europepmc   +1 more source

Ginkgolide A enhances cardiomyocyte differentiation from pluripotent stem cells by targeting cytochrome c to attenuate intrinsic apoptosis. [PDF]

J Biol Chem
Xu W, Wu X, Lei Z, Dang X, Shi H, Li J, Yuan L, Zhao Y, Li W, Chen J, Li N, Hua J.   +11 more
europepmc   +1 more source