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Plant-Derived Nutraceuticals in Mental Health and Brain Function: Mechanisms of Action and Therapeutic Potential. [PDF]
Int J Mol SciBorrego-Ruiz A, Borrego JJ.
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Construction of a globally modular recombinant <i>Saccharomyces cerevisiae</i> chassis for ginkgolide precursor levopimaradiene production. [PDF]
Synth Syst BiotechnolLiu +6 more
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Total Synthesis of Ginkgolide C and Formal Syntheses of Ginkgolides A and B
Journal of the American Chemical Society, 2022Ginkgolides are diterpenes isolated from Ginkgo biloba that exhibit strong anti-inflammatory and neuroprotective properties. The highly complex molecular architecture of ginkgolides, combined with their remarkable biological profile, provides a unique platform for the development of new strategies and methods.
Martin Hébert +2 more
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Preparation of a tritiated ginkgolide
Bioorganic & Medicinal Chemistry Letters, 2004Ginkgolide B, a constituent of the tree Ginkgo biloba, was radiolabeled with the beta-emitter tritium ([(3)H]) in two steps from ginkgolide C. First, a triflate precursor was prepared utilizing the selective reactivity of 7-OH in ginkgolide C; the triflate was then reduced with sodium borotritide to yield tritiated ginkgolide B ([(3)H]GB) in good yield
Strømgaard, Kristian +2 more
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Total Synthesis of (±)-Ginkgolide C and Formal Syntheses of (±)-Ginkgolide A and (±)-Ginkgolide B
2022Ginkgolides are naturally occurring compounds that can be extracted from the Ginkgo Biloba tree. Their synthesis remains a significant challenge for organic chemists given their complex structure and their numerous stereocenters (2 adjacent quaternary carbons and up to 12 stereocenters).
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Chemistry of the Ginkgolides, V. On the Preparation of the Ginkgolide Skeleton
Liebigs Annalen der Chemie, 1993Abstract3,14‐Didehydro‐10‐hydroxyginkgolideOn the nomenclature: The skeleton of the ginkgolides A, B, C, M and J with the natural configuration is called “ginkgolide” since the systematic IUPAC nomenclature is too complicated. According to our nomenclature ginkgolide “A” is 3,10‐dihydroxyginkgolide, ginkgolide “B” is 1,3,10‐trihydroxyginkgolide etc ...
Klaus Weinges +3 more
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