Results 161 to 170 of about 1,719 (204)

[Effect of compatibility of ginkgolide A, ginkgolide B and ginkgolide K].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2019
To investigate the best active compatibility of ginkgolide A, B and K (GA，GB，GK). The effects of GA, GB, GK alone, combinations of each two of them, and combinations of these three components on platelet-activating factor (PAF)-induced platelet aggregation activity and rat cerebral ischemia reperfusion model (tMCAO) were compared in this study ...
Hong, Zhang, Yan-Ping, Luo, Ze-Yu, Cao, Xin-Zhuang, Zhang, Liang, Cao, Zhen-Zhong, Wang, Wei, Xiao   +6 more
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Chemistry of the Ginkgolides. Part 10: Access to 14C-Labelled Ginkgolide A

Tetrahedron, 2000
Abstract In four reaction steps, ginkgolide A ( 1 ) was synthesized from the enol-acetate 3 , which is available in six steps from 1 . The key step was the reaction of the α-epoxy-acetate 4 with the lithium enolate of methyl propionate to give the compounds 5 and 6 . 14 C-Labelled ginkgolide A, which is of interest for pharmacological studies,
Klaus Weinges, Hartmut Schick, Hermann Irngartinger, Thomas Oeser   +3 more
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Three ginkgolide hydrates fromGinkgo bilobaL.: ginkgolide A monohydrate, ginkgolide C sesquihydrate and ginkgolide J dihydrate, all determined at 120 K

Acta Crystallographica Section C Crystal Structure Communications, 2002
A low-temperature structure of ginkgolide A monohydrate, (1R,3S,3aS,4R,6aR,7aR,7bR,8S,10aS,11aS)-3-(1,1-dimethylethyl)-hexahydro-4,7b-dihydroxy-8-methyl-9H-1,7a-epoxymethano-1H,6aH-cyclopenta[c]furo[2,3-b]furo[3',2':3,4]cyclopenta[1,2-d]furan-5,9,12(4H)-trione monohydrate, C(20)H(24)O(9) x H(2)O, obtained from Mo K alpha data, is a factor of three more
Jianping, Zhao, Ilias, Muhammad, D Chuck, Dunbar, Ikhlas A, Khan, Nikolaus H, Fischer, Frank R, Fronczek   +5 more
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Pharmacokinetics and tissue distribution of ginkgolide A, ginkgolide B, and ginkgolide K after intravenous infusion of ginkgo diterpene lactones in a rat model

Journal of Pharmaceutical and Biomedical Analysis, 2016
Ginkgo diterpene lactones are compounds that are extracted from the Ginkgo biloba leaf and possess pharmacologic activities with neuroprotective effects. To address the poor bioavailability of ginkgo diterpene lactones, ginkgo diterpene lactone meglumine injection (GDLI) was formulated and is commercially available.
Shuyao, Wang, Bingchen, Ouyang, Jiye, Aa, Jianliang, Geng, Fei, Fei, Pei, Wang, Jiankun, Wang, Ying, Peng, Ting, Geng, Yanjing, Li, Wenzhe, Huang, Zhenzhong, Wang, Wei, Xiao, Guangji, Wang   +13 more
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ChemInform Abstract: Chemistry of the Ginkgolides. Part 5. Preparation of the Ginkgolide Skeleton.

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
K. WEINGES, M. RUEMMLER, H. SCHICK, G. SCHILLING   +3 more
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Characterizations of the hydrolyzed products of ginkgolide A and ginkgolide B by liquid chromatography coupled with mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis, 2016
Ginkgolides are diterpenoid trilactones responsible for the neuromodulatory properties of Ginkgo biloba extracts. They are to be hydrolyzed in aqueous solutions as mixed carboxylate forms potentially including three monocarboxylates, three dicarboxylates and one tricarboxylate.
Ke, Lan, Xue-Jing, Li, Gang, Du, Liang, Xu   +3 more
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Chemie der Ginkgolide, II. Isolierung und Strukturaufklärung eines neuen Ginkgolids

Liebigs Annalen der Chemie, 1987
AbstractAus Blättern des Ginkgo‐Baumes wird ein neues Ginkgolid (5) isoliert, das wir als Ginkgolid J bezeichnen. Die Strukturaufklärung gelang sowohl mit spektroskopischen Methoden als auch durch chemischen Korrelation mit Ginkgolid C.
Klaus Weinges, Michael Hepp, Hermann Jaggy   +2 more
openaire   +1 more source

Extraction of ginkgolides from Ginkgo biloba

China Journal of Chinese Matera Medica, 2010
To establish the technology for extraction of ginkgolides from Ginkgo Biloba with alcohol-water.The parameters such as alcohol concentration, pH of extracting solution, ratio of dosage liquor, temperature and time, the extraction of ginkgolides from G.
Jun, He, Shuo, Yang, Jianian, Yang, Xiaohong, Qing   +3 more
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Extraction, isolation and purification for Ginkgolide B

China Journal of Chinese Materia Medica, 2010
To establish a simple extraction, isolation and purification method for ginkgolide B from ginkgo leaf.The optimum conditions of extraction, isolation and purification were studied by taking the transfer rate of ginkgolide B as index.Ginkgo leaf was extracted with 70% ethanol for three times, the extracts were concentrated to remove ethanol and diluted ...
Chenfeng, Zhang, Minghui, Li, Yun, Tang, Yanhai, Zhang, Min, Shi, Longsheng, Sheng   +5 more
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Determination of the derivative from ginkgolide B

Natural Product Research, 2008
A new compound decomposed from ginkgolide B(GB) is discovered and identified by MS and UV spectrum. It is the dehydrate of GB, which was named as ginkgolide K before. Differently, it cannot exist independently, but only in equilibrium with GB. It is found first time that 3-hydroxy is active in some solvent.
Chuanxun, Yuan, Jian, Pan, Xueqiao, Hu
openaire   +2 more sources