Results 31 to 40 of about 1,719 (204)
Mixed antagonistic effects of the ginkgolides at recombinant human ρ1 GABAC receptors [PDF]
, 2012 The diterpene lactones of Ginkgo biloba, ginkgolides A, B and C are antagonists at a range of Cys-loop receptors. This study examined the effects of the ginkgolides at recombinant human ρ1 GABAC receptors expressed in Xenopus oocytes using two-electrode ...
Thompson, Andrew J. +6 more
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Molecules, 2021 The present study compared the effects of natural senescence and methyl jasmonate (JA-Me) treatment on the levels of terpene trilactones (TTLs; ginkgolides and bilobalide), phenolic acids, and flavonoids in the primary organs of Ginkgo biloba leaves ...
Marcin Horbowicz +5 more
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Ginkgo biloba leaf extract EGb 761® as a paragon of the product by process concept
Frontiers in Pharmacology, 2022 It is an often-neglected fact that extracts derived from the very same plant can differ significantly in their phytochemical composition, and thus also in their pharmacokinetic and pharmacodynamic properties which are the basis for their clinical ...
Žarko Kulić +3 more
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Frontiers in Systems Neuroscience, 2020 The inflammatory immune response (IIR) is a physiological or excessive systemic response, induced by inflammatory immune cells according to changes in the internal and external environments.
Chunrong Li +4 more
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Total synthesis of ginkgolide a [PDF]
Tetrahedron Letters, 1988 Ginkgolide A (1) has been synthesized from the trilactone 3 and also from ginkgolide B (2).
E J, Corey, Arun K, Ghosh
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Ginkgolide B inhibits the neurotoxicity of prions or amyloid-β1-42
Journal of Neuroinflammation, 2004 Background Neuronal loss in Alzheimer's or prion diseases is preceded by the accumulation of fibrillar aggregates of toxic proteins (amyloid-β1-42 or the prion protein).
Williams Alun, Salmona Mario, Bate Clive
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Transformation of multi-component ginkgolide into ginkgolide B by Coprinus comatus [PDF]
BMC Biotechnology, 2015 As the strongest antagonist of the platelet activating factor, ginkgolide B (GB) possesses anti-ischemic, anti-oxidant and anti-convulsant properties, and it is used for the treatment of thrombosis in clinical practice. Till now, GB is usually obtained from extraction of Ginkgo biloba leaves through column chromatography with an extremely low yield and
Ding, HongXue +4 more
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Nature Communications, 2022 Although ginkgo terpenoids have been studied extensively for their pharmaceutical properties, knowledge on their biosynthesis remains limited. Here, the authors identify five multifunctional cytochrome P450s that catalyze the generation of the tert-butyl
Victor Forman +8 more
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Herbal medicines from ginkgo leaf extract in the treatment of mild dementia [PDF]
Arhiv za farmaciju, 2020 According to current EU monograph of the Committee on Herbal Medicinal Products of European Medicines Agency (EMA/HMPC) for ginkgo leaf, Ginkgonis folium (Ginkgo biloba, Ginkgoaceae), herbal medicines prepared from refined and quantified dry extract of ...
Petrović Silvana, Ušjak Ljuboš
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Effect of exogenous gibberellin on endogenous hormone and ginkgolide content in Ginkgo leaves
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2020 Ginkgolide is one of the important secondary metabolites of Ginkgo biloba. The synthesis of plant secondary metabolites is influenced by exogenous phytohormones. In this study, ten-year-old ginkgo grafted seedlings were used as the test material, and the
Xian ZHANG +5 more
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