Results 11 to 20 of about 2,581 (218)
Biomedicine and Pharmacotherapy, 2016 Ginkgolides are the major bioactive components of Ginkgo biloba extracts, however, the exact constituents of Ginkgolides contributing to their pharmacological effects remain unknown. Herein, we have determined the anti-inflammatory effects of Ginkgolide B (GB) and Ginkgolides mixture (GM) at equivalent dosages against lipopolysaccharide (LPS)-induced ...
Wei Shi, Ximei Wu
exaly +3 more sources
Ginkgolide A attenuated apoptosis via inhibition of oxidative stress in mice with traumatic brain injury [PDF]
HeliyonTraumatic brain injury (TBI) is the main cause of death among young adults and the main cause of mortality and disability for all ages groups worldwide.
Lei Zhu +4 more
doaj +2 more sources
Second-Generation Crystalline Sponges Enabling Consistent Structure Analysis Under Standardized Conditions for Diverse Molecules. [PDF]
Angew Chem Int Ed EnglThe second‐generation crystalline sponge method allows structurally diverse molecular guests to crystallize under standardized crystallization conditions. The key is the predominant packing type of cages and anions in crystals. ABSTRACT Crystallization is typically highly sensitive to even minor structural differences in target molecules.
He W, Takezawa H, Fujita M.
europepmc +3 more sources
The efficacy and safety of ginkgo terpene lactone preparations combined with antiplatelet aents in the treatment of ischemic stroke: a systematic review and meta-analysis [PDF]
Frontiers in PharmacologyBackgroundThis meta-analysis aimed to assess the efficacy and safety of ginkgo terpene lactone preparations including diterpene ginkgolides meglumine injection (DGMI) and ginkgolide injection combined with antiplatelet drugs in the treatment of ischemic ...
Hong Xu +4 more
doaj +2 more sources
Natural Chiral Scaffolds in Alzheimer's Disease: Therapeutic Potential, Mechanism, and Clinical Aspects. [PDF]
Biomed Res IntAlzheimer′s disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive impairment, amyloid‐β deposition, tau pathology, oxidative stress, neuroinflammation, and dysfunction of synapses. Current therapeutic options are largely symptomatic and lack disease‐modifying efficacy.
Singh A, Sahu SK, Sah AK.
europepmc +2 more sources
Ginkgo biloba leaf extract EGb 761® as a paragon of the product by process concept
Frontiers in Pharmacology, 2022 It is an often-neglected fact that extracts derived from the very same plant can differ significantly in their phytochemical composition, and thus also in their pharmacokinetic and pharmacodynamic properties which are the basis for their clinical ...
Žarko Kulić +3 more
doaj +1 more source
Molecules, 2021 The present study compared the effects of natural senescence and methyl jasmonate (JA-Me) treatment on the levels of terpene trilactones (TTLs; ginkgolides and bilobalide), phenolic acids, and flavonoids in the primary organs of Ginkgo biloba leaves ...
Marcin Horbowicz +5 more
doaj +1 more source
Molecules, 2022 Ginkgolide is a unique terpenoid natural compound in Ginkgo biloba, and it has an important medicinal value. Proper selenium has been reported to promote plant growth and development, and improve plant quality, stress resistance, and disease resistance ...
Linling Li +7 more
doaj +1 more source
Frontiers in Systems Neuroscience, 2020 The inflammatory immune response (IIR) is a physiological or excessive systemic response, induced by inflammatory immune cells according to changes in the internal and external environments.
Chunrong Li +4 more
doaj +1 more source
Total synthesis of ginkgolide a [PDF]
Tetrahedron Letters, 1988 Ginkgolide A (1) has been synthesized from the trilactone 3 and also from ginkgolide B (2).
E J, Corey, Arun K, Ghosh
openaire +2 more sources