Results 71 to 80 of about 1,719 (204)

Ginkgolides and bilobalide: Their physical, chromatographic and spectroscopic properties

, 2005
Ginkgolides A, B, C, J, K, L and M and bilobalide are rare terpene trilactones that have been isolated from leaves and root bark of the Chinese tree Ginkgo biloba.
Beek, T.A., van, van Beek, T.A.
core   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

Simultaneous Determination of Flavonols and Terpene Lactones in Beagle Dog Plasma by Ultra-Performance Liquid Chromatography-Tandem - Mass Spectrometry: 1. Method Development [PDF]

, 2015
Purpose: To develop an ultra-performance liquid chromatography-tandem mass spectrometry (UPLCMS/MS) method for the simultaneous determination of 7 major components of Ginkgo leaf (kaempferol, quercetin, isorhamnetin, ginkgolides A, ginkgolides B ...
Li, P, Liu, H, Cheng, Y, Feng, J, Lu, Y, Wu, H, Du, S, Shao, B   +7 more
core   +1 more source

Functional Characterization of the Levopimaradiene Synthase in and Differences in Functional Expression Patterns in Distinct Cell Lines

Natural Product Communications, 2019
Levopimaradiene and dehydroabietane are two direct precursors of ginkgolides and exist only in the root tissue of Ginkgo biloba . To study the biosynthesis of ginkgolide, we chose undifferentiated G.
Wenjin Zhang, Zhongyi Guo, Jincai Liang, Xiaofeng Lu, Shan Chen, Jianhua Zhu, Rongmin Yu   +6 more
doaj   +1 more source

The Contents of Terpene Trilactone and Flavonoid in Leaves of Seedlings from Ancient Female Ginkgo Trees in China

Horticultural Plant Journal, 2017
Flavonoids and terpene trilactones, especially, ginkgo flavonglycosides, ginkgolides and bilobalides in leaves of ginkgo trees, need to be studied for effective application of these active components with high medical and health-care values.
Yanhui ZHANG, Peiying LIU, Qianqian KONG, Shiyan XING, Xiaojing LIU, Limin SUN   +5 more
doaj   +1 more source

Ginkgolide B Alleviates Airway Inflammation in Hyperoxia Lung Injury

Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.
ABSTRACT Background Bronchopulmonary dysplasia (BPD) is a chronic lung disease characterized by inflammation, often caused by prolonged hyperoxia exposure in preterm infants. Platelet‐activating factor (PAF) is a potent inflammatory mediator, but its role in BPD is unclear.
Xuesong Wang, Mingwu Chen, Yong Lv, Yue Qi, Dake Huang, ShuShu Wang   +5 more
wiley   +1 more source

Simultaneous Determination of Flavonols and Terpene Lactones in Beagle Dog Plasma by Ultra-Performance Liquid Chromatography-Tandem - Mass Spectrometry: 2. Application to Pharmacokinetic Studies on Ginkgo Leaf Extract [PDF]

, 2015
Purpose: To evaluate the pharmacokinetics of the major compounds in Ginkgo leaf dosage formulations (namely, Yikangning tablets, Ginaton tablets, Aoshi dropping pills and Yinxinke dispersible tablets), commonly used in traditional Chinese medicine ...
Lu, Ya, Li, P, Liu, H, Cheng, Y, Feng, J, Wu, H, Du, S, Shao, B   +7 more
core   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, Volume 7, Issue 2, March 2026.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

Reduction of Ginkgotoxin and Ginkgolic Acids in Ginkgo biloba Seed Extracts Using a Multistep Liquid–Liquid Extraction Approach

Seeds
Ginkgo biloba seeds are a rich source of flavonoids and the unique terpene lactones—ginkgolides and bilobalide, known for their neuroprotective and cognitive-improving effects.
Teodora Tomova, Atanas Senin, Erol Eshrefov, Desislav Tomov, Iva Slavova, Mariana Argirova   +5 more
doaj   +1 more source

Neuronutraceuticals for Alzheimer's Disease Treatment: A Systematic Review of Randomised Controlled Trials Over the Last 20 Years

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
This PROSPERO‐registered review analysed 37 RCTs on neuronutraceuticals for Alzheimer's disease. Despite diverse targets—amyloid/tau, inflammation, oxidative stress, metabolism, synaptic plasticity, cholinergic and hormonal—the evidence was of low quality. RoB2 flagged attrition (86.5%) and reporting bias (81%). Current data do not support clinical use;
Mehmet Akif Topcuoglu, Esen Saka
wiley   +1 more source