Results 81 to 90 of about 30,545 (193)

Serine Protease Inhibitory Activity of Kampo Medicines: One of the Mechanisms Against Cold Syndrome

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
Serine protease inhibitory activity is involved in the mechanism of Kampo medicines used for treating common cold symptoms Ryokankyomishingeninto exhibited serine protease inhibitory activity in vitro and in vivo. Ryokankyomishingeninto showed anti‐SARS‐CoV‐2 activity in VeroE6/TMPRSS2 cells. ABSTRACT Aim Serine proteases play a key role in coronavirus
Yukiko Matsuo, Reina Akaiwa, Miku Yanagioka, Mishizu Kikuchi, Yuuna Kawahara, Takuma Yoshida, Hidemasa Nakaminami, Niro Inaba, Yoshihiro Mimaki   +8 more
wiley   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, Volume 7, Issue 4, August 2026.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

Affordances, dread, and online fraud: Exploring and advancing social learning theory in online contexts

Criminology, Volume 64, Issue 3, Page 698-733, August 2026.
Abstract We investigate how the affordances of an online context shape the processes of social learning. Using a dataset of more than 11,000 posts from the fraud subdread on the dark web forum Dread, we examine how affordances of platform governance, connectivity, anonymity, invisibility, asynchronicity, and limited oversight influence the components ...
Fangzhou Wang, Timothy Dickinson
wiley   +1 more source

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, Volume 117, Issue 8, Page 2064-2084, August 2026.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

S3‐Leitlinie Diagnostik und Therapie der Alopecia areata – Teil 2: Therapie, psychosoziale und kosmetische Unterstützung

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page 1155-1179, August 2026.
Zusammenfassung In diesem zweiten Teil der S3‐Leitlinie zur Diagnostik und Therapie der Alopecia areata (AA) stellen wir die zentralen Inhalte und Empfehlungen zur topischen und systemischen Therapie, zur Lebensqualität und zu Unterstützungsangeboten vor.
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

S3 guideline diagnostics and therapy in alopecia areata – Part 2: Therapy, psychosocial and cosmetic support

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 8, Page e1155-e1177, August 2026.
Summary This second part of the S3 guideline on the diagnosis and treatment of alopecia areata (AA), presents key recommendations on topical and systemic therapy, quality of life and support services. The first part of the guideline, published separately, covers the definition and content of epidemiology and diagnosis as well as comorbidities, risk and
Ulrike Blume‐Peytavi, Andria Constantinou, Tsenka Tomova‐Simitchieva, Adrian Tanew, Michael Sticherling, Hermann Girschick, Annika Vogt, Uwe Schwichtenberg, Uwe Gieler, André Märtens, Kerstin Zienert, Claudia Stenders, Ricardo Niklas Werner, Doris Wilborn   +13 more
wiley   +1 more source

Evaluation of confirmatory data following the Article 12 MRL review and setting of an import tolerance for fluopyram in limes

EFSA Journal, Volume 24, Issue 8, August 2026.
Abstract The applicant Bayer AG Crop Science Division submitted a request to the competent national authority in Germany to evaluate the confirmatory data for the active substance fluopyram that were identified in the maximum residue levels (MRLs) review under Article 12 of Regulation (EC) No 396/2005.
European Food Safety Authority (EFSA), Giulia Bellisai, Giovanni Bernasconi, Irene Castellan, Monica del Aguila, Lucien Ferreira, Renata Leuschner, Andrea Mioč, Marta Szot, Manuela Tiramani, Alessia Verani   +10 more
wiley   +1 more source

Analysis of the Variation in Antioxidant Activity and Chemical Composition upon the Repeated Thermal Treatment of the By-Product of the Red Ginseng Manufacturing Process

Molecules
Steamed ginseng water (SGW) is a by-product of the repeated thermal processing of red ginseng, which is characterized by a high bioactive content, better skin care activity, and a large output.
Yu-Dan Wang, Hui-E Zhang, Lu-Sheng Han, Gen-Yue Li, Kai-Li Yang, Yuan Zhao, Jia-Qi Wang, Yang-Bin Lai, Chang-Bao Chen, En-Peng Wang   +9 more
doaj   +1 more source

Analysis of Ginsenoside Isomers by Inlet Ionization-High Resolution Mass Spectrometry

Zhipu Xuebao
The ginsenoside isomers were analyzed and distinguished by using inlet ionization-high resolution mass spectrometry technology under positive and negative ion modes with optimum inlet temperatures.
Yun-long GUO, Hong-yue CHI, Yang WANG, Fei ZHENG, Yu-lin DAI, Xin HUANG, Hao YUE, Shu-ying LIU   +7 more
doaj   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

FEBS Open Bio
Etoposide, an anticancer drug that inhibits topoisomerase II, is commonly used in combination chemotherapy. However, the impact of O‐GlcNAcylation regulation on etoposide's anticancer effects has rarely been investigated.
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung‐Cheol Han, Mijin Kwon, Seung‐Ho Lee   +5 more
doaj   +1 more source