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Ginseng Omics for Ginsenoside Biosynthesis
Current Pharmaceutical Biotechnology, 2021Ginseng, also known as the king of herbs, has been regarded as an important traditional medicine for several millennia. Ginsenosides, a group of triterpenoid saponins, have been characterized as bioactive compounds of ginseng. The complexity of ginsenosides hindered ginseng research and development both in cultivation and clinical research. Therefore,
Xianmei Yin +5 more
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Photochemistry and Photobiology, 2019
AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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AbstractGinsenosides are compounds responsible for the primary pharmacological effects of American ginseng. Compound‐Y (C‐Y) is a minor ginsenoside and a metabolite of Panax ginseng. In this study, we investigated the protective effect of ginsenoside UVB‐irradiated NHDFs and its potential for use as an antihyperpigmentation agent through ginsenoside C ...
Xiao‐yi Liu +4 more
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Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia
Biotechnology Letters, 2006Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong beta-glucosidase-producing activity, converted ginsenoside Rb(1) to the active metabolites by 91%.
Le-Qin, Cheng +4 more
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Journal of Food Engineering, 2012
Abstract This study developed a method for enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng. The method began with targets extraction from herbal material, followed by HPD300 resins separation, then extracted by water-statured n-butanol.
Jianing Mi +5 more
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Abstract This study developed a method for enriched separation of protopanaxatriol ginsenosides, malonyl ginsenosides and protopanaxadiol ginsenosides from Panax ginseng. The method began with targets extraction from herbal material, followed by HPD300 resins separation, then extracted by water-statured n-butanol.
Jianing Mi +5 more
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Analysis methods of ginsenosides
Journal of Chromatography B, 2004Ginsenosides are considered the main active principles of the famous Chinese traditional medicine "ginseng". For more than 30 years many researchers developed methods for the identification and quantification of ginsenosides in ginseng plant material, extracts and products.
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Synthesis of Ocotillol-Type Ginsenosides
The Journal of Organic Chemistry, 2016A total of 14 ocotillol-type ginsenosides were conveniently synthesized employing glycosylation of ocotillol sapogenin derivatives with glucosyl ortho-alkynylbenzoate donors under the promotion of a gold(I) catalyst as the key step. Relying on a rational protecting group strategy and the unexpected regioselectivity of the glycosylation of the 3,25-diol
Renzeng, Shen +4 more
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Facile Synthesis of Ginsenoside Ro
Synlett, 2004Two concise synthetic routes, being different in the glycosylation sequence, toward ginsenoside Ro (1) are developed. These syntheses feature the elaboration of the glucuronide residue at a later stage via the TEMPO-mediated selective oxidation and the installation of AZMB as a benzoylic neighboring participating group capable of being selectively ...
Wenjie Peng +4 more
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