Results 71 to 80 of about 16,277 (170)

Development of a Validated UPLC-MS/MS Method for Analyzing Major Ginseng Saponins from Various Ginseng Species

Molecules, 2019
Ginsenosides, which contain one triterpene and one or more sugar moieties, are the major bioactive compounds of ginseng. The aim of this study was to develop and optimize a specific and reliable ultra-performance liquid chromatography-tandem mass ...
Ling Yang, Chi-Lin Li, Yung-Yi Cheng, Tung-Hu Tsai   +3 more
doaj   +1 more source

Antiallergic Activity of Ginsenoside Rh2

Biological & Pharmaceutical Bulletin, 2003
The antiallergic activities of ginsenosides, which were isolated from acid-treated ginseng (Panax ginseng, Araliaceae), and their metabolites by human intestinal bacteria were measured. Ginsenoside Rh2, which is a main metabolite, had the most potent inhibitory activity on beta-hexosaminidase release from RBL-2H3 cells and in the passive cutaneous ...
Eun-Kyung, Park, Min-Kyung, Choo, Eun-Jin, Kim, Myung Joo, Han, Dong-Hyun, Kim   +4 more
openaire   +3 more sources

Ginsenosides from Heat Processed Ginseng

Chemical and Pharmaceutical Bulletin, 2009
A new dammarane-glycoside, ginsenoside Rz1 (1), was isolated from heat-treated Panax ginseng C. A. MEYER (Araliaceae) with ginsenosides Rk1 and Rg5. The structure of 1 was established to be (Z)-12beta-hydroxydammara-20(22),24-dien-3beta-yl O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucospyranoside by spectroscopic means.
Sang Myung, Lee, Hyun Ju, Shon, Chung-Sig, Choi, Tran Manh, Hung, Byung Sun, Min, Kihwan, Bae   +5 more
openaire   +3 more sources

Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway

Journal of Inflammation Research, 2022
Chenyang Zhang,1 Meixin Han,2 Xuelian Zhang,1 Hongna Tong,1 Xiaobo Sun,1 Guibo Sun1 1Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2College of Pharmacy,
Zhang C, Han M, Zhang X, Tong H, Sun X, Sun G   +5 more
doaj  

Ginsenoside Rk3 alleviates retinal pigment epithelial cell senescence by enhancing autophagy via mTOR inhibition

陆军军医大学学报
Objective To investigate the role and mechanism of ginsenoside Rk3 in alleviating the senescence of retinal pigment epithelial (RPE) cells and in treating neovascular age-related macular degeneration (nAMD).
HE Feixiang, HE Feixiang, LIU Xuemei, TANG Qian   +3 more
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Biotransformation of Ginsenoside Rb1 to Ginsenoside Rd and 7 Rare Ginsenosides Using Irpex lacteus with HPLC-HRMS/MS Identification

ACS Omega
The biotransformation of ginsenosides using microorganisms represents a promising and ecofriendly approach for the production of rare ginsenosides. The present study reports on the biotransformation of ginsenoside Rb1 using the fungus Irpex lacteus, resulting in the production of ginsenoside Rd and seven rare ginsenosides with novel structures ...
Yue Gao, Yadong Feng, Yanyan Chang, Zhu Zhu, Huanxi Zhao, Wei Xu, Mengya Zhao, Yusheng Xiao, Lu Tian, Yang Xiu   +9 more
openaire   +3 more sources

Ginsenoside Rb1 ameliorates neutrophil extracellular traps-induced vascular endothelial damage by suppressing apoptosis

Bangladesh Journal of Pharmacology
The study aims to investigate the effect of ginsenoside Rb1 on improving neutrophil extracellular traps-induced vascular endothelial damage. The CCK8 assay was used to evaluate the impact of ginsenoside Rb1 on cell activity.
Biao Zhang, Junkai Zhao, Jiamin Yin, Jiaping Chen, Lingqi Xu   +4 more
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Inhibition mechanisms and hypolipidemic effects on lipase of saponins from Panax japonicas var. major leaves

Guangxi Zhiwu
The dry aerial part of Panax japonicus var. major is called “Zhuzishen Ye”, it is a characteristic Chinese herbal medicine in Qinba area. In order to rationally develop and utilize “Zhuzishen Ye” and clarify its chemical constituents, the main chemical ...
ZHENG Huachan, MENG Lingru, HE Miao, HUANG Wenli, DAN Linwei, XU Hong, DENG Chong, ZHANG Huawei, JIANG Yi, SONG Xiaomei   +9 more
doaj   +1 more source

Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments

Current Issues in Molecular Biology
While Ginsenoside Re has been shown to protect the central nervous system, reports of its effects on memory in the model of scopolamine-induced memory impairment are rare.
Xin Li, Kai Zheng, Hao Chen, Wei Li
doaj   +1 more source

Ginsenoside Re promotes osteogenic differentiation via BMP2/p38 pathway in vivo and in vitro

Journal of Ginseng Research
Background: Ginsenosides have been used in traditional Chinese medicine to treat fractures. Ginsenoside Re, a key component of P. ginseng, however, the molecular mechanisms underlying these effects remain inadequately understood.
Yunjia Wang, Gengming Zhang, Linhua Deng, Hongqi Zhang, Emmanuel Alonge, Zhongjing Jiang   +5 more
doaj   +1 more source