Results 81 to 90 of about 17,143 (196)

Ginsenoside Rh2 regulates triple-negative breast cancer proliferation and apoptosis via the IL-6/JAK2/STAT3 pathway

Frontiers in Pharmacology
IntroductionTriple-negative breast cancer (TNBC) is the most challenging subtype of breast cancer to treat. While previous studies have demonstrated that ginsenoside Rh2 induces apoptosis in TNBC cells, the specific molecular targets and underlying ...
Rumeng Ding, Quancheng Kan, Ting Wang, Ran Xiao, Yanan Song, Duolu Li   +5 more
doaj   +1 more source

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, Volume 22, Issue 45, 13 August 2026.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Analysis of Saponins in Two Processed American Ginseng Products Based on UHPLC-Q-Orbitrap-MS/MS

Zhipu Xuebao
Ultra-high performance liquid chromatography-quadrupole-electrostatic field orbital trap high-resolution mass spectrometry (UHPLC-Q-Orbitrap-MS/MS) was used to analyze the saponin components in sun-dried American ginseng and red American ginseng.
Ye JING, Li-wen LIANG, Yu-lin DAI, Fei ZHENG, Yang WANG, Xin HUANG, Yun-long GUO, Hao YUE   +7 more
doaj   +1 more source

Exploratory Analysis of Biomarkers Predictive or Reflective of Ninjin'yoeito Efficacy in Patients With Loss of Appetite or Apathy Attributable to Dementia

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
ABSTRACT Aim This study explored biomarkers related to patient characteristics and the efficacy of Ninjin'yoeito (NYT), a traditional Japanese Kampo medicine, by conducting omics (metabolomic and microbiomic) analyses of plasma and stool samples obtained during a randomized controlled trial targeting anorexia and apathy in patients with dementia ...
Masashi Tamura, Taro Shindo, Katsutoshi Furukawa, Kei Suzuki, Kunihiro Konno, Shiori Ishizawa, Yasuharu Mizuhara, Takashi Matsumoto, Mitsue Nishiyama, Hitomi Kanno, Tetsuaki Arai   +10 more
wiley   +1 more source

Ginsenoside Rk3 alleviates retinal pigment epithelial cell senescence by enhancing autophagy via mTOR inhibition

陆军军医大学学报
Objective To investigate the role and mechanism of ginsenoside Rk3 in alleviating the senescence of retinal pigment epithelial (RPE) cells and in treating neovascular age-related macular degeneration (nAMD).
HE Feixiang, HE Feixiang, LIU Xuemei, TANG Qian   +3 more
doaj   +1 more source

Ginsenoside Rb1 Protects Against Diabetic Cardiomyopathy by Regulating the Adipocytokine Pathway

Journal of Inflammation Research, 2022
Chenyang Zhang,1 Meixin Han,2 Xuelian Zhang,1 Hongna Tong,1 Xiaobo Sun,1 Guibo Sun1 1Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, People’s Republic of China; 2College of Pharmacy,
Zhang C, Han M, Zhang X, Tong H, Sun X, Sun G   +5 more
doaj  

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, Volume 117, Issue 8, Page 2064-2084, August 2026.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Ginsenoside Rb1 ameliorates neutrophil extracellular traps-induced vascular endothelial damage by suppressing apoptosis

Bangladesh Journal of Pharmacology
The study aims to investigate the effect of ginsenoside Rb1 on improving neutrophil extracellular traps-induced vascular endothelial damage. The CCK8 assay was used to evaluate the impact of ginsenoside Rb1 on cell activity.
Biao Zhang, Junkai Zhao, Jiamin Yin, Jiaping Chen, Lingqi Xu   +4 more
doaj   +1 more source

Ginsenoside Re Regulates Oxidative Stress through the PI3K/Akt/Nrf2 Signaling Pathway in Mice with Scopolamine-Induced Memory Impairments

Current Issues in Molecular Biology
While Ginsenoside Re has been shown to protect the central nervous system, reports of its effects on memory in the model of scopolamine-induced memory impairment are rare.
Xin Li, Kai Zheng, Hao Chen, Wei Li
doaj   +1 more source

Biotransformation of Ginsenoside Rb1 to Ginsenoside Rd and 7 Rare Ginsenosides Using Irpex lacteus with HPLC-HRMS/MS Identification

ACS Omega
The biotransformation of ginsenosides using microorganisms represents a promising and ecofriendly approach for the production of rare ginsenosides. The present study reports on the biotransformation of ginsenoside Rb1 using the fungus Irpex lacteus, resulting in the production of ginsenoside Rd and seven rare ginsenosides with novel structures ...
Yue Gao, Yadong Feng, Yanyan Chang, Zhu Zhu, Huanxi Zhao, Wei Xu, Mengya Zhao, Yusheng Xiao, Lu Tian, Yang Xiu   +9 more
openaire   +3 more sources