Results 1 to 10 of about 9,296 (235)

Pharmacokinetics study of ginsenoside Rg1 liposome by pulmonary administration [PDF]

Heliyon
Ginsenoside Rg1 (Rg1), a monomer saponin component, is one of the components with the highest content in total saponins of Panaxnotoginseng. It had various pharmacological effects.
Ping Liang, Jie Zhang, Juan Hou, Rui Feng, Jintuo Yin   +4 more
doaj   +4 more sources

Does ginsenoside Rg1 promote intervertebral disc repair? An experimental study insights into ferroptosis mechanism [PDF]

Journal of Translational Medicine
Background Intervertebral disc degeneration (IVDD) is a complex and multifactorial condition characterized by the progressive deterioration of the intervertebral discs.
Dongliang Gong, Feiyun Xia, Fuyong Wang, Xiaoxia Tong, Qing Yang, Kelv Shen, Baihan Sun, Nong Chen, Zhengfeng Lu   +8 more
doaj   +2 more sources

A novel strategy for the protective effect of ginsenoside Rg1 against ovarian reserve decline by the PINK1 pathway [PDF]

Pharmaceutical Biology
Context The decline in ovarian reserve is a major concern in female reproductive health, often associated with oxidative stress and mitochondrial dysfunction.
Pengdi Yang, Meiling Fan, Ying Chen, Dan Yang, Lu Zhai, Baoyu Fu, Lili Zhang, Yanping Wang, Rui Ma, Liwei Sun   +9 more
doaj   +2 more sources

Ginsenoside Rg1 Ameliorates Pulmonary Hypertension by Inhibiting cGAS/STING Mediated Cell Senescence [PDF]

Drug Design, Development and Therapy
Rongzhen Ding,1– 3 Haiping Xie,4 Yu Zhang,2,3 Li Qin,3,5 Guoran Peng,2,3 Jian Yi,2,3 Junlan Tan,6 Xianya Cao,2,3 Runxiu Zheng,2,3 Aiguo Dai2 1Department of Health Management, The First Hospital of Hunan University of Chinese Medicine, Changsha, Hunan ...
Ding R, Xie H, Zhang Y, Qin L, Peng G, Yi J, Tan J, Cao X, Zheng R, Dai A   +9 more
doaj   +2 more sources

New Therapeutic Approaches to and Mechanisms of Ginsenoside Rg1 against Neurological Diseases [PDF]

Cells, 2022
Neurological diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD), stroke, cerebral infarction, ischemia-reperfusion injury, depression and, stress, have high incidence and morbidity and often lead to ...
Yang Sun, Yantao Yang, Shasha Liu, Songwei Yang, Chen Chen, Meiyu Lin, Qi Zeng, Junpeng Long, Jiao Yao, Fan Yi, Lei Meng, Qidi Ai, Naihong Chen   +12 more
doaj   +2 more sources

Inhibition of caspase-1 by ginsenoside Rg1 ameliorates d-gal-induced renal aging and injury through suppression of oxidative stress and inflammation [PDF]

Renal Failure
Background The disruption of renal cell homeostasis caused by aging has attracted considerable attention. A traditional Chinese medicine, ginseng, is a potential drug for treating aging-related diseases. The study investigates the effect and mechanism of
Tingting Guo, Ting Xie, Xuejun Chen, Jingying Zhong, Zhenyu Bai, Huiyu Liang, Xiaoshan Zhao, Meixia Fang, Ya Xiao, Jun Zhang   +9 more
doaj   +2 more sources

Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis [PDF]

Frontiers in Pharmacology
BackgroundThe pathological progression from liver injury to fibrosis is a hallmark of liver disease, with no effective strategies to halt this transition.
Lijuan Dan, Xiuyan Li, Shuanglan Chen, Xiaojie You, Dong Wang, Tianyuan Wang, Jia Li, Wenping Liu, Jie Mu, Quansheng Feng, Quansheng Feng   +10 more
doaj   +2 more sources

Ginsenoside Rg1 alleviates HG-induced autophagy of retinal microvascular endothelial cells by activating ACE2/Ang1-7/Mas in vitro. [PDF]

Sci Rep
Chen Y, Jin Y.
europepmc   +2 more sources

Ginsenoside Rg1 inhibits angiogenesis in diabetic retinopathy through the miR-100-3p/FBXW7/c-MYC molecular axis. [PDF]

J Diabetes Investig
Xue L, Hu M, Li Y, Zhu Q, Zhou G, Zhang X, Zhou Y, Zhang J, Ding P.   +8 more
europepmc   +3 more sources

Ginsenoside Rg1 controls CKLF1-mediated apoptosis to reduce hypoxic/reoxygenation injury in HT22 cells. [PDF]

Front Pharmacol
Liang J, Zhu X, Li F, Yang Y, Zhu Y, Liu S, Sun Y, Kuang B, Long J, Yan Q, Lin Y, Ai Q, Yang Y.   +12 more
europepmc   +2 more sources