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Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. [PDF]
PLoS ONE, 2014 Neurogenesis continues throughout the lifetime in the hippocampus, while the rate declines with brain aging. It has been hypothesized that reduced neurogenesis may contribute to age-related cognitive impairment. Ginsenoside Rg1 is an active ingredient of
Jiahong Zhu +9 more
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Immunomodulating Activity of Ginsenoside Rg1 from Panax Ginseng
Japanese Journal of Pharmacology, 1990 The immunomodulatory activity of ginsenoside Rg1 from Panax ginseng was studied in mice using sheep red cells as the antigen. It was found that ginsenoside Rg1 at a dose of 10 mg/kg administered for three consecutive days before immunization increased the number of spleen plaque-forming cell, the titers of sera hemagglutinins as well as the number of ...
B, Kenarova +3 more
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Cellular Physiology and Biochemistry, 2017 Background/Aims: Excessive reactive oxygen species (ROS) disturb the physiology of H9c2 cells, which is regarded as a major cause of H9c2 cardiomyocyte apoptosis.
Qianhui Li +4 more
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Frontiers in Nutrition, 2021 The restriction and banning of antibiotics in farm animal feed has led to a search for promising substitutes for antibiotics to promote growth and maintain health for livestock and poultry.
Zehe Song +14 more
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Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors [PDF]
, 2015 Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes.
Adinolfi +48 more
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Brazilian Journal of Medical and Biological Research, 2017 Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LPS ...
X.J. Ni +5 more
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Oral Rg1 supplementation strengthens antioxidant defense system against exercise-induced oxidative stress in rat skeletal muscles [PDF]
, 2012 BACKGROUND: Previous studies reported divergent results on nutraceutical actions and free radical scavenging capability of ginseng extracts. Variations in ginsenoside profile of ginseng due to different soil and cultivating season may contribute to the ...
Chia-Hua Kuo +10 more
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Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells [PDF]
Frontiers in Pharmacology, 2020 Recently, breakthroughs have been made in the use of mesenchymal stem cells (MSCs) to treat various diseases. Several stem cell types have been authorized as drugs by the European Medicines Agency and the U.S. Food and Drug Administration. The Chinese official document "Notification of the management of stem cell clinical research (trial)" was also ...
Fang He +4 more
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A multivariate analysis on the comparison of raw notoginseng (Sanqi) and its granule products by thin-layer chromatography and ultra-performance liquid chromatography [PDF]
, 2015 Background: Granule products produced from medicinal herbs are gaining popularity. However, there have been few studies comparing the quality or efficacy of granules with those of herbal formulations.
Chan, K, Razmovski-Naumovski, V, Zhou, X
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Journal of Pharmacological Sciences, 2009 Ginsenoside Rg1 has been reported to improve cognitive function in many memory-impaired animal models. However, little is known about the bioactivity of its metabolites in the central nervous system in vivo.
Yu-Zhu Wang +6 more
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