Results 21 to 30 of about 9,296 (235)

Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands. [PDF]

, 2013
The aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor that mediates many of the biological and toxicological actions of structurally diverse chemicals.
Bonati, Laura, Denison, Michael S, Fraccalvieri, Domenico, He, Guochun, Hu, Qin, Soshilov, Anatoly, Xie, Qunhui, Yin, Huijun, Zhang, Aiqian, Zhao, Bin, Zhao, Jing   +10 more
core   +9 more sources

Ginsenoside Rg1 can reverse fatigue behavior in CFS rats by regulating EGFR and affecting Taurine and Mannose 6-phosphate metabolism

Frontiers in Pharmacology, 2023
Background: Chronic fatigue syndrome (CFS) is characterized by significant and persistent fatigue. Ginseng is a traditional anti-fatigue Chinese medicine with a long history in Asia, as demonstrated by clinical and experimental studies.
Chaofang Lei, Jiaxu Chen, Jiaxu Chen, Zhen Huang, Yinian Men, Yue Qian, Mingzhi Yu, Xinyi Xu, Lin Li, Xin Zhao, Youming Jiang, Yueyun Liu   +11 more
doaj   +1 more source

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy

Journal of Ginseng Research, 2023
Alzheimer's disease (AD) is a common form of dementia, and impaired mitophagy is a hallmark of AD. Mitophagy is mitochondrial-specific autophagy. Ginsenosides from Ginseng involve in autophagy in cancer. Ginsenoside Rg1 (Rg1 hereafter), a single compound of Ginseng, has neuroprotective effects on AD.
Ni Wang, Junyan Yang, Ruijun Chen, Yunyun Liu, Shunjie Liu, Yining Pan, Qingfeng Lei, Yuzhou Wang, Lu He, Youqiang Song, Zhong Li   +10 more
openaire   +3 more sources

Ginsenoside Rg1 inhibits nucleus pulposus cell apoptosis, inflammation and extracellular matrix degradation via the YAP1/TAZ pathway in rats with intervertebral disc degeneration

Journal of Orthopaedic Surgery and Research, 2022
Purpose Intervertebral disc degeneration (IDD) is one of the main causes of low back pain, which not only affects patients’ life quality, but also places a great burden on the public health system.
Yong-hua Yang, Xiao-peng Gu, Hong Hu, Bin Hu, Xiang-lian Wan, Zhi-ping Gu, Shao-jin Zhong   +6 more
doaj   +1 more source

Ginsenoside Rg1 inhibits multiple myeloma and overcomes bortezomib resistance through AMPK-mTOR pathway. [PDF]

Heliyon
Lin L, Chen D, Li S, Wang T.
europepmc   +2 more sources

Ginsenoside Rg1 as a promising adjuvant agent for enhancing the anti-cancer functions of granulocytes inhibited by noradrenaline

Frontiers in Immunology, 2023
IntroductionIn recent years, numerous studies have confirmed that chronic stress is closely related to the development of cancer. Our previous research showed that high levels of stress hormones secreted in the body during chronic stress could inhibit ...
Yuqian Zhu, Jingyao Chen, Jun Li, Chenqi Zhou, Xin Huang, Bingdi Chen   +5 more
doaj   +1 more source

Host miR-129-5p reverses effects of ginsenoside Rg1 on morphine reward possibly mediated by changes in B. vulgatus and serotonin metabolism in hippocampus

Gut Microbes, 2023
Morphine addiction is closely associated with dysbiosis of the gut microbiota. miRNAs play a crucial role in regulating intestinal bacterial growth and are involved in the development of disease.
Chan Li, Yingbo Lin, Rukun Lin, Zhijie Chen, Qichun Zhou, Chaohua Luo, Zhixian Mo   +6 more
doaj   +1 more source

Ginsenoside Rg1 promotes endothelial progenitor cell migration and proliferation [PDF]

Acta Pharmacologica Sinica, 2009
To investigate the effect of ginsenoside Rg1 on the migration, adhesion, proliferation, and VEGF expression of endothelial progenitor cells (EPCs).EPCs were isolated from human peripheral blood and incubated with different concentrations of ginsenoside Rg1 (0.1, 0.5, 1.0, and 5.0 micromol/L) and vehicle controls.
Ai-wu, Shi, Xiao-bin, Wang, Feng-xiang, Lu, Min-min, Zhu, Xiang-qing, Kong, Ke-jiang, Cao   +5 more
openaire   +2 more sources

Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3

Animals, 2023
Abnormal function and the fibrosis of endometrium caused by endometritis in cows may lead to difficult embryo implantation and uterine cavity adhesions. Emerging evidence indicates that ginsenoside Rg1 can effectively resist inflammation and pathological
Liangli Song, Linnan Wang, Xiangchen Li, Longfei Xiao   +3 more
doaj   +1 more source

Activities of β-Glucosidase and α-L-Arabinofuranosidase from Cordyceps militaris and Their Applications in the Transformation of Ginsenoside Rg1 and Rc [PDF]

Shipin Kexue, 2023
In this study, a strain of Cordyceps militaris with high productivity of β-glucosidase was identified and selected. The effects of carbon source, nitrogen source and pH value on the production of β-glucosidase, α-L-arabinofuranosidase, cordyceps acid and
LI Fei, HUANG Qiuting, SUI Xin, XIE Ying
doaj   +1 more source