Results 51 to 60 of about 20,751 (192)
Frontiers in Cellular and Infection Microbiology, 2023 Objectives This study aimed to investigate the protective effect of ginsenoside Rg3 (GRg3) against acute radiation proctitis (ARP) in rats. Methods Wistar rats were randomly divided into control, model, dexamethasone-positive, GRg3 low-dose, GRg3 medium ...
Xiaoyu Duan +7 more
semanticscholar +1 more source
Open Chemistry, 2018 Ginsenoside Rg3(S) is a primary bioactive component in ginseng, which has pharmacological effects and nutritional activities. In the present study, pulsed electric field (PEF)-assisted acid hydrolysis processing was used to convert major ginsenoside Rb1 ...
Lu Chengwen, Yin Yongguang
doaj +1 more source
Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice
Journal of Ginseng Research, 2019 Background: Gastric ulcer (GU) is a common gastrointestinal disease that can be induced by many factors. Finding an effective treatment method that contains fewer side effects is important.
Kai Zhang +7 more
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Ginsenoside Rg3 for Chemotherapy-Induced Myelosuppression: A Meta-Analysis and Systematic Review
Frontiers in Pharmacology, 2020 Patients with advanced cancer often undergo myelosuppression after receiving chemotherapy. However, severe myelosuppression results in treatment delay, and some can even be life-threatening.
Linlin Pan +4 more
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The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside
Journal of Ginseng Research, 2022 Colon cancer, the third most frequent occurred cancer, has high mortality and extremely poor prognosis. Ginsenoside, the active components of traditional Chinese herbal medicine Panax ginseng, exerts antitumor effect in various cancers, including colon ...
Xin Sun +8 more
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International Journal of Molecular Medicine, 2022 Acute pancreatitis (AP) is an inflammatory disorder that has been associated with systemic inflammatory response syndrome. Ginsenoside Rg3 is a major active component of Panax ginseng, which has been demonstrated to exert potent protective effects on ...
Y. Shan +5 more
semanticscholar +1 more source
Journal of Ginseng Research, 2014 The transformation of ginsenoside Rb1 into a specific minor ginsenoside using Aspergillus niger KCCM 11239, as well as the identification of the transformed products and the pathway via thin layer chromatography and high performance liquid chromatography
Kyung Hoon Chang +3 more
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Advances in Polymer Technology, 2020 Objective. To explore the effects and mechanism of ginsenoside Rg3 nanoparticles on the malignant behavior of non-small-cell lung cancer. Methods. The nanoparticle carriers were prepared by using an electrostatic system, and the coverage of ginsenoside ...
Weizheng Zhou +4 more
doaj +1 more source
Ginsenoside Rg3, a Gating Modifier of EAG Family K+ Channels [PDF]
Molecular Pharmacology, 2016 Ginsenoside 20(S)-Rg3 (Rg3) is a steroid glycoside that induces human ether-à-go-go-related gene type 1 (hERG1, Kv11.1) channels to activate at more negative potentials and to deactivate more slowly than normal. However, it is unknown whether this action is unique to hERG1 channels. Here we compare and contrast the mechanisms of actions of Rg3 on hERG1
Wei, Wu +3 more
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PLoS ONE, 2017 ObjectiveThis study aimed to investigate the link between the inhibitory effect of ginsenoside Rg3 on the ectopic endometrium growth and the VEGFR-2-mediated PI3K/Akt/mTOR signaling pathway, a mechanism known to inhibit angiogenesis and induce ectopic ...
Yang Cao +9 more
doaj +1 more source