Results 61 to 70 of about 631 (158)
Taxonomic Distribution of Medicinal Plants for Alzheimer’s Disease: A Cue to Novel Drugs
International Journal of Alzheimer’s Disease, Volume 2020, Issue 1, 2020., 2020 Alzheimer’s disease (AD) is a neurodegenerative disorder manifested by decline in memory and mild cognitive impairment leading to dementia. Despite global occurrence of AD, the severity and hence onset of dementia vary among different regions, which was correlated with the customary use of medicinal herbs and exposure level to the causatives.
Muhammad Kamran +9 more
wiley +1 more source
Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division [PDF]
, 2020 A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable of generating oligodendrocytes
Encinas Pérez, Juan Manuel +6 more
core +2 more sources
, 2022 Ginseng is the most well-known Chinese medicine as well as one of the most used herbal medicines. It has a wide range of medical and pharmacological uses.
core +1 more source
Frontiers in Pharmacology, 2018 Gintonin is a ginseng-derived lysophosphatidic acid receptor (LPAR) ligand. Although previous in vitro and in vivo studies demonstrated the therapeutic role of gintonin against Alzheimer’s disease, the neuroprotective effects of gintonin in Parkinson’s ...
Jong Hee Choi +7 more
doaj +1 more source
Natural products with therapeutic potential in melanoma metastasis [PDF]
, 2015 Malignant melanoma is the most aggressive form of skin cancer and accounts for about 3% of all cases of malignant tumour. Its incidence is increasing worldwide and it is becoming resistant to current therapeutic agents.
AlQathama, A, Prieto, JM
core +1 more source
Frontiers in Pharmacology, 2021 Alzheimer’s disease (AD), a neurodegenerative disorder, is a major health concern in the increasingly aged population worldwide. Currently, no clinically effective drug can halt the progression of AD. Panax ginseng C.A. Mey.
Jing Li +9 more
doaj +1 more source
Gintonin facilitates catecholamine secretion from the perfused adrenal medulla
The Korean Journal of Physiology & Pharmacology, 2016 The present study was designed to investigate the characteristics of gintonin, one of components isolated from Korean Ginseng on secretion of catecholamines (CA) from the isolated perfused model of rat adrenal gland and to clarify its mechanism of action.
Na, Seung-Yeol +4 more
openaire +2 more sources
Journal of Ginseng Research, 2019 Background: Gintonin is a ginseng-derived exogenous ligand of the G protein-coupled lysophosphatidic acid (LPA) receptor. We previously reported that gintonin stimulates gliotransmitter release in primary cortical astrocytes. Astrocytes play key roles in
Sun-Hye Choi +9 more
doaj +1 more source
Lysophosphatidic Acid and Glutamatergic Transmission [PDF]
, 2019 Signaling through bioactive lipids regulates nervous system development and functions. Lysophosphatidic acid (LPA), a membrane-derived lipid mediator particularly enriched in brain, is able to induce many responses in neurons and glial cells by affecting
Ana Peñalver +4 more
core +2 more sources
Gintonin enhances epithelial barrier function by activating NRF2 pathway in radiation-induced intestinal injury. [PDF]
J Ginseng ResBACKGROUND: Because the intestine is a radio-sensitive organ in the body, and radiation-induced intestinal injury is a major clinical problem associated with radiotherapy or radiological accidents. Dysfunction of the epithelial barrier leads to bacterial translocation to other organs, resulting in severe inflammation.
Jang H +6 more
europepmc +2 more sources