Results 71 to 80 of about 739 (165)

Taxonomic Distribution of Medicinal Plants for Alzheimer’s Disease: A Cue to Novel Drugs

International Journal of Alzheimer’s Disease, Volume 2020, Issue 1, 2020., 2020
Alzheimer’s disease (AD) is a neurodegenerative disorder manifested by decline in memory and mild cognitive impairment leading to dementia. Despite global occurrence of AD, the severity and hence onset of dementia vary among different regions, which was correlated with the customary use of medicinal herbs and exposure level to the causatives.
Muhammad Kamran, Rehana Kousar, Shakir Ullah, Siraj Khan, Muhammad Farooq Umer, Haroon Ur Rashid, Zakir Khan, Muhammad Ijaz Khan Khattak, Mujeeb Ur Rehman, Francesco Panza   +9 more
wiley   +1 more source

Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division [PDF]

, 2020
A population of neural stem cells (NSCs) dwelling in the dentate gyrus (DG) is able to generate neurons throughout adult life in the hippocampus of most mammals. These NSCs generate also astrocytes naturally and are capable of generating oligodendrocytes
Encinas Pérez, Juan Manuel, Estivill Torrús, Guillermo, Martín Suárez, Soraya, Muro García, Teresa, Pastor Alonso, Oier, Rodríguez de Fonseca, Fernando, Valcárcel Martín, Roberto   +6 more
core   +1 more source

Ginseng [PDF]

, 2022
Ginseng is the most well-known Chinese medicine as well as one of the most used herbal medicines. It has a wide range of medical and pharmacological uses.

core   +1 more source

Natural products with therapeutic potential in melanoma metastasis [PDF]

, 2015
Malignant melanoma is the most aggressive form of skin cancer and accounts for about 3% of all cases of malignant tumour. Its incidence is increasing worldwide and it is becoming resistant to current therapeutic agents.
AlQathama, A, Prieto, JM
core   +1 more source

Neuroprotective Potentials of Panax Ginseng Against Alzheimer’s Disease: A Review of Preclinical and Clinical Evidences

Frontiers in Pharmacology, 2021
Alzheimer’s disease (AD), a neurodegenerative disorder, is a major health concern in the increasingly aged population worldwide. Currently, no clinically effective drug can halt the progression of AD. Panax ginseng C.A. Mey.
Jing Li, Qingxia Huang, Qingxia Huang, Jinjin Chen, Hongyu Qi, Jiaqi Liu, Zhaoqiang Chen, Daqing Zhao, Zeyu Wang, Xiangyan Li   +9 more
doaj   +1 more source

Gintonin facilitates catecholamine secretion from the perfused adrenal medulla

The Korean Journal of Physiology & Pharmacology, 2016
The present study was designed to investigate the characteristics of gintonin, one of components isolated from Korean Ginseng on secretion of catecholamines (CA) from the isolated perfused model of rat adrenal gland and to clarify its mechanism of action.
Na, Seung-Yeol, Kim, Ki-Hwan, Choi, Mi-Sung, Ha, Kang-Su, Lim, Dong-Yoon   +4 more
openaire   +2 more sources

Lysophosphatidic Acid and Glutamatergic Transmission [PDF]

, 2019
Signaling through bioactive lipids regulates nervous system development and functions. Lysophosphatidic acid (LPA), a membrane-derived lipid mediator particularly enriched in brain, is able to induce many responses in neurons and glial cells by affecting
Ana Peñalver, Carolina Roza, Javier Márquez, José A. Campos-Sandoval, María C. Gómez-García   +4 more
core   +2 more sources

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance [PDF]

, 2021
Metastatic melanoma is challenging to clinically address. Although standard-of-care targeted therapy has high response rates in patients with BRAF-mutant melanoma, therapy relapse occurs in most cases. Intrinsically resistant melanoma cells drive therapy
Alicea, Gretchen M., Amaravadi, Ravi K., Aza-Blanc, Pedro, Beqiri, Marilda, Boland, Genevieve M., Brafford, Patricia, Cheng, Chaoran, Connelly, Thomas, Delvadia, Bela, Delvadia, Maya, Flaherty, Keith T., Frederick, Dennie T., Fukunaga-Kalabis, Mizuho, Gutierrez, Alexis, Herlyn, Meenhard, Hristova, Denitsa M., Huang, Ye, Karakousis, Giorgos C., Kossenkov, Andrew V., Krepler, Clemens, Kwong, Lawrence N., Li, Ling, Liu, Jianglan, Liu, Qin, Lu, Yiling, Mills, Gordon B., Mitchell, Tara C., Morias, Alice S., Rebecca, Vito W., Ronai, Ze'ev A., Salvino, Joseph M., Samarkina, Anastasia, Schuchter, Lynn M., Somasundaram, Rajasekharan, Speicher, David W., Sproesser, Katrin, Tong, Cynthia, Vultur, Adina, Wang, Joshua X., Wei, Zhi, Wu, Lawrence W., Xiao, Min, Xu, Wei, Xu, Xiaowei, Yang, Chih Cheng, Zayasbazan, Delaine, Zhang, Gao, Zhang, Jie   +47 more
core   +1 more source

Mechanisms of Panax ginseng action as an antidepressant

Cell Proliferation, Volume 52, Issue 6, November 2019., 2019
Abstract Objectives Panax ginseng, a well‐known traditional Chinese medicine with multiple pharmacological activities, plays a crucial role in modulating mood disorders. Several recent studies have identified an underlying role of Panax ginseng in the prevention and treatment of depression. However, the cellular and molecular mechanisms remain unclear.
Yang Jin, Ranji Cui, Lihong Zhao, Jie Fan, Bingjin Li   +4 more
wiley   +1 more source

Anti‐Inflammatory Activity of Rg3‐Enriched Korean Red Ginseng Extract in Murine Model of Sepsis

Evidence-Based Complementary and Alternative Medicine, Volume 2018, Issue 1, 2018., 2018
Ginseng has therapeutic effects on various bodily disorders ranging from minor inflammation to major cardiovascular diseases. In our study, we explored the anti‐inflammatory effects of Rg3‐enriched red ginseng extract (Rg3‐RGE), a ginsenoside belonging to the panaxadiol group.
Evelyn Saba, Dahye Jeong, Muhammad Irfan, Yuan Yee Lee, Sang-Joon Park, Chae-Kyu Park, Man Hee Rhee, José L. Rios   +7 more
wiley   +1 more source