Role of Lysophosphatidic Acid in Neurological Diseases: From Pathophysiology to Therapeutic Implications [PDF]
Lysophosphatidic acid (LPA), a bioactive lipid molecule, has been identified as a critical regulator of several cellular processes in the central nervous system, with significant impacts on neuronal function, synaptic plasticity, and neuroinflammatory ...
Avdoshina, Valeria +3 more
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The Relationship Between Vitamin D Status and Fall Risk in Elderly with Chronic Kidney Disease on Regular Hemodialysis [PDF]
, 2023 Introduction. Fall is one of the main causes of hospitalization in the elderly, which is caused by several factors including gait disturbances, balance disorders, visual disturbances, chronic kidney disease (CKD), vitamin D deficiency, and so on ...
Dina Aprillia Ariestine +2 more
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Pharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity [PDF]
, 2022 All forms of dementia including Alzheimer's disease are currently incurable. Mitochondrial dysfunction and calcium alterations are shown to be involved in the mechanism of neurodegeneration in Alzheimer's disease. Previously we have described the ability
Abramov, Andrey Y +10 more
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Journal of Ginseng Research, 2021 Background: Gintonin-enriched fraction (GEF) is a new non-saponin component glycolipoprotein isolated from ginseng root. This study examined the effect of GEF on age-related sarcopenia in old C57BL/6J mice.
Hyun-Ji Oh +3 more
doaj +1 more source
Plant‐Derived Treatments for Different Types of Muscle Atrophy
Phytotherapy Research, Volume 39, Issue 2, Page 1107-1138, February 2025.Potential mechanisms of phytoactive compounds in the treatment of muscle atrophy. ABSTRACT With the development of medicine and chemistry, an increasing number of plant‐derived medicines have been shown to exert beneficial therapeutic on the treatment of various physical and psychological diseases. In particular, by using physical chemistry methods, we
Xingpeng Wang +9 more
wiley +1 more source
Effects of a gintonin-enriched fraction on hair growth: an in vitro and in vivo study
Journal of Ginseng Research, 2020 Background: Ginseng has been widely used as a health-promoting tonic. Gintonin present in ginseng acts as a lysophosphatidic acid (LPA) receptor ligand that activates six LPA receptor subtypes. The LPA6 subtype plays a key role in normal hair growth, and
Na-Eun Lee +11 more
doaj +1 more source
Panax Ginseng in the treatment of Alzheimer's disease and vascular dementia
Journal of Ginseng Research, 2023 Dementia has become one of the most important diseases threatening human health. Alzheimer's disease (AD) and vascular dementia (VaD) have the highest incidence rates among the types of dementia, but until now, therapeutic methods have been limited ...
Zhiyong Wang +4 more
doaj +1 more source
The alteration of chloride homeostasis/GABAergic signaling in brain disorders: Could oxidative stress play a role? [PDF]
, 2021 In neuronal precursors and immature neurons, the depolarizing (excitatory) effect of γ-Aminobutyric acid (GABA) signaling is associated with elevated [Cl−]i; as brain cells mature, a developmental switch occurs, leading to the decrease of [Cl−]i and to ...
Abruzzo P. M., Marini M., Panisi C.
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Practicum: The CQT “How To” & “Why To” [PDF]
, 2017 Publikacja recenzowana / Peer-reviewed ...
Amsel, Tuvya T.
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Panax ginseng as an adjuvant treatment for Alzheimer's disease
Journal of Ginseng Research, 2018 Longevity in medicine can be defined as a long life without mental or physical deficits. This can be prevented by Alzheimer's disease (AD). Current conventional AD treatments only alleviate the symptoms without reversing AD progression.
Hyeon-Joong Kim +7 more
doaj +1 more source