Results 171 to 180 of about 72,161 (311)

Semaglutide and tirzepatide effects on cardiovascular outcomes in people with overweight or obesity in the real world (STEER)

Diabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2403-2415, March 2026.
Abstract Aims To assess the real‐world effectiveness of semaglutide versus tirzepatide in reducing major adverse cardiovascular events (MACE) among patients with overweight/obesity and established atherosclerotic cardiovascular disease (ASCVD) without diabetes in an insured US population.
Lauren Wilson, Zhenxiang Zhao, Victoria Divino, Matthew Bassan, Bríain Ó. Hartaigh, Signe Stensen, Kerem Ozer   +6 more
wiley   +1 more source

Haptic Feedback and the Role of Need for Touch on Augmented Reality Mobile Shopping Apps

International Journal of Consumer Studies, Volume 50, Issue 2, March 2026.
ABSTRACT As mobile commerce has become increasingly prevalent, retailers have sought to enhance the mobile shopping experience by incorporating multisensory stimulation (i.e., visual, auditory, and now tactile stimulation). This paper investigates the presence of sensory inputs, specifically haptic feedback, when positioning and manipulating augmented ...
Margot Racat, Ryann Reynolds, Michael Obal   +2 more
wiley   +1 more source

Coupling and Bernoullicity in random-cluster and Potts models

, 2001
An explicit coupling construction of random-cluster measures is presented. As one of the applications of the construction, the Potts model on amenable Cayley graphs is shown to exhibit at every temperature the mixing property known as ...
Haggstrom, Olle, Jonasson, Johan, Lyons, Russell   +2 more
core   +2 more sources

LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept

Molecular Metabolism, 2018
T. Coskun, K. Sloop, C. Loghin, Jorge Alsina-Fernandez, S. Urva, K. Bokvist, Xuewei Cui, Daniel A. Briere, Over Cabrera, William Roell, U. Kuchibhotla, J. Moyers, C. Benson, R. Gimeno, D. D’Alessio, A. Haupt   +15 more
semanticscholar   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, Volume 600, Issue 3, Page 324-333, February 2026.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

NDR2 regulates non-small cell lung cancer cell migration under starvation by supporting autophagosome biogenesis through LC3 and ATG9A regulation

Cell Death Discovery
Non-small cell lung cancer (NSCLC) is characterized by the deregulation of the Hippo kinase NDR2 and high basal autophagic activity. NDR2 promotes autophagy-driven tumor growth in some cancers, but evidence in lung cancer is lacking.
Tiphaine Biojout, Emmanuel Bergot, Jasmine Taylor, Dimitri Leite Ferreira, Nathalie Colloc’h, Marc Riffet, Nicolas Elie, Maelle Guyot, Céline Bazille, Jérôme Levallet, Guénaëlle Levallet   +10 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, Volume 15, Issue 5, 2 February 2026.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Brukertilpasset gips

, 2019
Denne tekniske rapporten tar for seg utvikling og konstruksjon av en løsning som er designet for å erstatte dagens gipsprosess ved håndleddsbrudd. Løsningen innebærer å 3D-skanne en hånd og 3D-printe en brukertilpasset gipsskinne, og baserer seg på en tidligere hovedoppgave fra 2017. Denne prosessen skulle automatiseres ved å bruke dagens 3D-teknologi,
Sjåstad, Denis, Alvestad, Vegard Justsen André, Nedrelid, Oscar Hatlo   +2 more
openaire   +1 more source

An experimental medicine protocol for exploring the haemodynamic effects of dual agonism at the glucagon‐like peptide‐1 and glucagon receptor in healthy subjects

British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 579-588, February 2026.
Aims Glucagon‐like peptide‐1 (GLP‐1) and glucagon dual receptor agonists are in clinical development for a range of metabolic conditions, including type 2 diabetes and obesity. The cardiovascular actions at these receptors are well studied, but less is known about their combination.
James Goodman, Victoria E. Parker, Carmel M. McEniery, Giovanni Di Stefano, Annette Hubsch, Evangelia Vamvaka, Jo Helmy, Fotini Kaloyirou, Navazh Jalaludeen, Peter Barker, Lutz Jermutus, Joseph Cheriyan, Philip Ambery, Ian B. Wilkinson   +13 more
wiley   +1 more source

Severe Euglycemic Diabetic Ketoacidosis Requiring Intubation After Tirzepatide and SGLT2 Inhibitor Coadministration in a Patient With Type 1 Diabetes Mellitus From a Large Tertiary Care Centre in Karachi, Pakistan: A Case Report and Brief Review of the Literature

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Euglycemic diabetic ketoacidosis (euDKA) is an uncommon but potentially life‐threatening complication that may arise in patients treated with incretin‐based therapies or Sodium–Glucose Cotransporter‐2 (SGLT2) inhibitors. We report a 41‐year‐old female with Type 1 Diabetes Mellitus (T1DM) who developed severe euDKA after initiating tirzepatide ...
Maliha Malik, Hammad Amjad, Khadija Malik, Muddassir Syed Saleem, Shanzay Akhtar, Muslehuddin Paracha, Mobeen Abid, Nabahat Shafi, Ahmed Asad Raza, Abedin Samadi, Samar Abbas Jaffri   +10 more
wiley   +1 more source