Type 2 Diabetes Mellitus: Molecular Pathogenesis and Therapeutic Interventions
This graphical summary illustrates the multiorgan therapeutic landscape for Type 2 diabetes mellitus (T2D), integrating molecular pathogenesis with modern treatment strategies. It depicts how current interventions, including SGLT2 inhibitors, GLP‐1 receptor agonists, and insulin secretagogues, target key organs—kidney, pancreas, gastrointestinal tract,
Shinuan Fei +9 more
wiley +1 more source
The Role of Glucose-Dependent Insulinotropic Polypeptide (GIP) in Bone Metabolism. [PDF]
Lin A +8 more
europepmc +1 more source
Reproducibility of Splanchnic Blood Flow Measured Using Phase‐Contrast MRI
Splanchnic vessel blood flow assessment can describe physiology or pathophysiological conditions. Here, we assessed the variation of PC‐MRI‐determined repeated measures of blood flow in four splanchnic vessels in three populations and two MRI‐scanners. We found similar agreements with the means for both scanners and for healthy individuals and patients
Lærke S. Gasbjerg +11 more
wiley +1 more source
A Review of Lifestyle Interventions Provided as an Adjunct to Obesity Management Medications
ABSTRACT Objective This review synthesized the components of lifestyle interventions that have been provided in Phase 3 trials of obesity management medications (OMMs). Methods PubMed, CINAHL, and EMBASE were searched for Phase 3 clinical trials published from inception to February 2026 that tested FDA‐approved OMMs.
Ariana M. Chao +5 more
wiley +1 more source
Glucagon-Like Peptide-1 Receptor Agonists: Their Therapeutic Potential in Cystic Fibrosis. [PDF]
Panou T +3 more
europepmc +1 more source
Metabolic Dysfunction-Associated Steatotic Liver Disease and Incretin Receptor Agonists: A Metabolic Approach to Halting Liver Disease Progression. [PDF]
Abenavoli L +6 more
europepmc +1 more source
Incretin and Glucagon Signalling in MASLD and MASH: Integrating Metabolic Pathways With Disease Progression. [PDF]
Tsakiridis EE, Steinberg GR.
europepmc +1 more source
A DYRK inhibitor ameliorates glucose homeostasis and increases incretin-producing cells in diabetic mice. [PDF]
Terasaki M +3 more
europepmc +1 more source

