Results 241 to 250 of about 36,022 (296)
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Peptides, 1981
Two structurally similar peptides were isolated from a preparation of GIP using an HPLC system. The major peptide corresponds to GIP1-42 and the minor has the sequence GIP3-42. GIP1-42 has both insulinotropic and somatostatinotropic activities, whereas GIP3-42 has only insignificant activity.
Raymond A Pederson +2 more
exaly +3 more sources
Two structurally similar peptides were isolated from a preparation of GIP using an HPLC system. The major peptide corresponds to GIP1-42 and the minor has the sequence GIP3-42. GIP1-42 has both insulinotropic and somatostatinotropic activities, whereas GIP3-42 has only insignificant activity.
Raymond A Pederson +2 more
exaly +3 more sources
GIP’s effect on bone metabolism is reduced by the selective GIP receptor antagonist GIP(3–30)NH2
Bone, 2020 Infusion of the incretin hormone glucose-dependent insulinotropic polypeptide (GIP) suppresses the bone resorption marker carboxy-terminal type 1 collagen crosslinks (CTX). Using separate and combined infusions of the selective GIP receptor (GIPR) antagonist, GIP(3-30)NH2, and GIP, we investigated how GIPR inhibition affects bone turnover markers.
Lærke S. Gasbjerg +8 more
openaire +5 more sources
Peptides, 2020 Enzymatic cleavage of endogenous peptides is a commonly used principle to initiate, modulate and terminate action for instance among cytokines and peptide hormones.
Mette M. Rosenkilde +2 more
exaly +2 more sources
Glucose-dependent insulinotropic polypeptide (GIP) [PDF]
Molecular MetabolismBACKGROUND: Glucose-dependent insulinotropic polypeptide (GIP) was the first incretin identified and plays an essential role in the maintenance of glucose tolerance in healthy humans.
Timo D. Müller +2 more
exaly +5 more sources
GIP or not GIP? That is the question
Trends in Pharmacological Sciences, 2003Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that is released during a meal and facilitates the disposal of both glucose and fat. Because of the insulinotropic action of GIP, this hormone has been considered as a potential therapy of type 2 diabetes, where insulin secretion is inadequate.
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Proceedings of the first workshop on Wireless mobile internet, 2001
The GPRS and UMTS specifications define the procedures supporting the mobility and the data sessions of a mobile user moving within the area of the corresponding PLMNs. For the case, though, of mobile users working in group, using a PLMN infrastructure, the aforementioned networks foresee no special treatment.
Constantinos F. Grecas +2 more
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The GPRS and UMTS specifications define the procedures supporting the mobility and the data sessions of a mobile user moving within the area of the corresponding PLMNs. For the case, though, of mobile users working in group, using a PLMN infrastructure, the aforementioned networks foresee no special treatment.
Constantinos F. Grecas +2 more
openaire +2 more sources
The gastrocolic response: Is it gip?
Journal of Surgical Research, 1980Abstract Previous experiments demonstrated that feeding is followed by increased electrical spike discharges and contractions of colon smooth muscle. This gastrocolic response has a definite lag period before onset, and is not due to distention of the colon by food. In these experiments, the possible association between altered serum concentration of
L F, Sillin +4 more
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Obesity Surgery, 2010
Bariatric surgery is the most effective modality of achieving weight loss as well as the most effective treatment for type 2 diabetes mellitus (T2DM). Glucose-dependent insulinotropic polypeptide (GIP) is an incretin and is implicated in the pathogenesis of obesity and T2DM. Its role in weight loss and resolution of T2DM after bariatric surgery is very
Raghavendra S, Rao, Subhash, Kini
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Bariatric surgery is the most effective modality of achieving weight loss as well as the most effective treatment for type 2 diabetes mellitus (T2DM). Glucose-dependent insulinotropic polypeptide (GIP) is an incretin and is implicated in the pathogenesis of obesity and T2DM. Its role in weight loss and resolution of T2DM after bariatric surgery is very
Raghavendra S, Rao, Subhash, Kini
openaire +2 more sources
Regulatory development of geriatric medicines: To GIP or not to GIP?
Ageing Research Reviews, 2016Geriatric patients represent the main users of medicines, but are historically often minimally included in clinical trials, resulting in a gap in the knowledge of the benefit/risk balance of medicines in this heterogeneous population. As the worldwide population is aging, the need for safe and effective medicines for older patients is proportionally ...
Bart, De Spiegeleer +6 more
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Physiology of GIP - A Lesson from GIP Receptor Knockout Mice
Hormone and Metabolic Research, 2004A much greater insulin response is observed after oral glucose load than after intravenous injection of glucose. The hormonal factor(s) implicated as transmitters of signals from the gut to pancreatic beta-cells was referred to incretin; gastric inhibitory polypeptide or glucose-dependent insulinotropic polypeptide (GIP) is identified as one of the ...
Y, Yamada, Y, Seino
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