Results 211 to 220 of about 30,994 (308)
Merging T1D and T2D Management: Shared Strategies for Common Goals-Building on Early Lessons From GLP-1 Trials in T1D. [PDF]
Bergenstal RM, Willis HJ, Carlson AL.
europepmc +1 more source
Abstract Background Accurate dose deposition in superficial radiotherapy remains challenging due to the inherent skin‐sparing effect of megavoltage photon beams and difficulties in ensuring bolus conformity. Purpose This study aims to comprehensively evaluate the dosimetric characteristics of the room‐temperature‐malleable high‐density bolus, to ...
Jonathan Dadoun +15 more
wiley +1 more source
Modulation of the tumor microenvironment by incretins and glucagon: Metabolic and immune mechanisms (Review). [PDF]
Hu M, Jiang CJ, Yi C.
europepmc +1 more source
The graphical abstract summarizes the current evidence on the potential neuroprotective effects of tirzepatide (TZP), a dual GIP/GLP‐1 receptor agonist, across mechanistic, preclinical, and clinical domains. Mechanistically, TZP is proposed to exert direct neural effects, preserve mitochondrial function, reduce apoptosis, oxidative stress, and ...
Yousef Hawas +6 more
wiley +1 more source
Emerging Role of Dual Glucagon-Like Peptide-1 (GLP-1)/Glucose-Dependent Insulinotropic Polypeptide (GIP) Receptor Agonists in Cardiovascular Prevention. [PDF]
Contreras Figueroa N +5 more
europepmc +1 more source
ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley +1 more source
The attenuated incretin effect is associated with glucose intolerance in patients with hepatitis B-related acute-on-chronic liver failure. [PDF]
Li M +8 more
europepmc +1 more source
In this large real‐world propensity‐matched analysis, tirzepatide demonstrated superior reductions in mortality, hospitalizations, and cardiorenal outcomes versus dulaglutide in HFpEF patients, with a favorable safety profile. ABSTRACT Background No direct head‐to‐head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection ...
Ibrahim Khalil +8 more
wiley +1 more source
Endogenous GIP signaling is indispensable for DPP-4 inhibitor-mediated metabolic control in mice. [PDF]
Kubota-Okamoto S +17 more
europepmc +1 more source

