GLP-1, GIP, and Glucagon Excursions During a Mixed Meal Tolerance Test in Young and Lean South Asians Versus Europids. [PDF]
Hoekx CA +8 more
europepmc +1 more source
ABSTRACT Aims To evaluate the effect of tirzepatide on body weight, glycaemic control, insulin requirements, continuous glucose monitoring (CGM) metrics and cardiorenal parameters in adults with Type 1 diabetes (T1D) and overweight or obesity. Materials and Methods In this retrospective matched cohort study, adults with T1D, BMI ≥ 27 kg/m2, CGM use and
Amanda R. Purcell +3 more
wiley +1 more source
Dietary Strategies and Nutritional Management in Patients Receiving GLP-1 and Dual GIP/GLP-1 Receptor Agonists as Adjuncts to Lifestyle Interventions: A Systematic Review of Randomised Clinical Trials. [PDF]
de Paulo RS +3 more
europepmc +1 more source
Diagnosis and management of equine metabolic syndrome
Summary Equine metabolic syndrome (EMS) is a prevalent endocrine disorder that increases the risk of hyperinsulinaemia‐associated laminitis (HAL), the most common and clinically significant form of laminitis. The central pathological feature of EMS is insulin dysregulation (ID), which encompasses basal or postprandial hyperinsulinaemia and tissue ...
F. R. Bertin
wiley +1 more source
GIP receptor agonism suppresses inflammation-induced aversion and food intake via distinct circuits. [PDF]
Province HS +7 more
europepmc +1 more source
ABSTRACT Objective This work aimed to investigate the efficacy and safety of Roux‐en‐Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in adults with acquired hypothalamic obesity (HO). Design Systematic review and meta‐analysis. Methods Publications reporting relevant outcomes in patients with HO before and after RYGB or SG were identified through a
Johannes Fessler +3 more
wiley +1 more source
GIPR:GCGR co-agonism restores normal weight in obese rodents. [PDF]
Perez-Tilve D +8 more
europepmc +1 more source
Time‐dependent (Creep) Compaction in Volcanic Rocks
Abstract Porous volcanic rocks form volcanic edifices and host key geothermal reservoirs worldwide. When subjected to constant stress above dilatancy in the brittle regime, these materials undergo time‐dependent failure known as brittle creep. In the ductile regime, where deformation is compactive, time‐dependent compaction—compaction creep—has been ...
Kamal Bayramov +3 more
wiley +1 more source
Real-world 6-month persistence, adherence, and effectiveness of GLP-1 medications for overweight and obesity in a Medicaid population. [PDF]
Meyer KB +10 more
europepmc +1 more source
CtBP2, a transcriptional corepressor with metabolite sensing capabilities, maintains feeding homeostasis by preventing excessive food intake in the hypothalamic feeding center. CtBP2 limits food intake by inhibiting KLF4 within AgRP neurons and by promoting the inhibitory influence of POMC neurons on AgRP neurons.
Wanpei Chen +15 more
wiley +1 more source

