Results 141 to 150 of about 10,013 (222)

Therapeutic potential of targeting G protein-gated inwardly rectifying potassium (GIRK) channels in the central nervous system.

Pharmacology and Therapeutics, 2021
Danko Jeremic, Irene Sánchez‐Rodríguez, Lydia Jiménez‐Díaz, J. Navarro-López   +3 more
semanticscholar   +1 more source

GIRK channels in Alzheimer's disease.

Aging, 2020
Lieberman, Ori J, Bartolini, Francesca, Miniaci, Maria   +2 more
openaire   +3 more sources

Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity. [PDF]

Elife
Toyoda H, Kim D, Koh BG, Sano T, Kanematsu T, Oh SB, Kang Y.   +6 more
europepmc   +1 more source

Involvement of spinal G-protein inwardly rectifying potassium (GIRK) channels in the enhanced antinociceptive effects of the activation of both μ-opioid and cannabinoid CB1 receptors.

Journal of Pharmacological Sciences, 2022
Yoshinori Takemura, Yuka Sudo, T. Saeki, S. Kurata, Tsutomu Suzuki, T. Mori, Y. Uezono   +6 more
semanticscholar   +1 more source

Direct crosstalk between GPCRs and ion channels via G proteins. [PDF]

Exp Mol Med
Kim SH, Kim J, So I, Lee HH.
europepmc   +1 more source

Pre- and Post-synaptic Mechanisms of Neuronal Inhibition Assessed Through Biochemically Detailed Modeling of GABA_B Receptor Signaling. [PDF]

J Neurosci
Mäki-Marttunen T, Kismul JF, Pajo K, Schulz JM, Manninen T, Einevoll GT, Linne ML, Andreassen OA, Kotaleski JH.   +8 more
europepmc   +1 more source

Ion Channels and Osteoarthritic Pain: Potential for Novel Analgesics [PDF]

, 2013
A Denadai-Souza, A Dray, A Dray, A Gomis, A Mobasheri, A Mobasheri, A Mobasheri, A Mobasheri, A Okun, A Verkhratsky, AD Craig Jr, AD Wickenden, AM Malfait, AM Valdes, AT Rufino, B Heppelmann, B Liu, B Lofstrom, BL Kidd, C Cialdai, C Zöllner, C. A. Staunton, CG Faber, CL Baker, CT Chen, D Nockemann, DJ Hunter, DJ Hunter, DR Sagar, F Iannone, F Oliva, F-L Yuan, G Verbruggen, GR Dube, GS Banchet von, GS Hennig, H Ichikawa, H Katsura, H-G Schaible, HC Fan, IT Strickland, J Fernihough, J Huang, J Vriens, J-P Pelletier, JC Czeschik, JD Brederson, JL Vonsy, JP Huggins, JP Pelletier, K Ahn, K Kumagai, K Varani, KS Kang, KW Marshall, L Fernandes, L Pena Ede, M Bandell, M Grunke, M Ikeuchi, M Izumi, M Thakur, MA Caudill-Slosberg, MB Goldring, MF Jarvis, MJ Caterina, ML Brines, MM Knight, N Schuelert, N Schuelert, N Schuelert, P Cesare, P Creamer, P Zhang, PG Green, PI Mapp, R Chen, R Gao, R Lewis, R Lewis, R Lewis, R. Barrett-Jolley, R. Lewis, RA North, RJ Docherty, RJ Hatch, RW Crawford, RX Zhang, S Cotofana, S Just, S McGaraughty, S Meini, S Meini, S Suri, S Todorovic, SJ Kolker, SJ Millward-Sadler, SP Alexander, SR Bond, T Voets, TE Cawston, TW Jenkins, V Neugebauer, W Rahman, W Xie, WG Cho, Y Uchiyama, YT Konttinen, Z Helyes   +108 more
core   +1 more source

Estimation of Dopamine D₁ Receptor Agonist Binding Kinetics Using Time-Resolved Functional Assays: Relation to Agonist-Induced Receptor Internalization by Investigational Antiparkinsonian Therapeutics. [PDF]

ACS Chem Neurosci
Sahlholm K, Svensson P, Malo M, Andersson DR, Betari N.   +4 more
europepmc   +1 more source

Profiling the Impact of mGlu₇/Elfn1 Protein Interactions on the Pharmacology of mGlu₇ Allosteric Modulators. [PDF]

ACS Chem Neurosci
Lei X, Xiang Z, Rodriguez AL, Wilson ML, Niswender CM.   +4 more
europepmc   +1 more source

Cannabinoid Modulation of Excitability and Short-Term Neuronal Dynamics in the Dorsal and Ventral Hippocampus. [PDF]

Biology (Basel)
Tsotsokou G, Sotiropoulou IM, Stampolitis K, Oikonomou GD, Avdi AP, Papatheodoropoulos C.   +5 more
europepmc   +1 more source