Results 1 to 10 of about 148,764 (185)

The effect of concomitant DPPIVi use on glycaemic control and hypoglycaemia with insulin glargine 300 U/mL (Gla-300) versus insulin glargine 100 U/mL (Gla-100) in people with type 2 diabetes: A patient-level meta-analysis of EDITION 2 and 3. [PDF]

PLoS ONE, 2018
To evaluate the effect of concomitant dipeptidyl peptidase IV inhibitor (DPPIVi) use on efficacy and safety of insulin glargine 300 U/mL (Gla-300) versus glargine 100 U/mL (Gla-100) in people with type 2 diabetes on oral antihyperglycaemic drugs.A post ...
Jean-François Yale, Jeremy Hodson Pettus, Miguel Brito-Sanfiel, Fernando Lavalle-Gonzalez, Ana Merino-Trigo, Peter Stella, Soazig Chevalier, Raffaella Buzzetti   +7 more
doaj   +7 more sources

High efficiency reduction of 4-nitrophenol on greenly synthesized gold nanoparticles decorated on chitosan matrix (CS-GLA/AuNPs) [PDF]

Scientific Reports
An inexpensive bioinspired green approach using Saussurea costus root extract was developed to fabricate CS-GLA/AuNP catalyst for the reduction of 4-nitrophenol (4-NP) to 4-aminophenol (4-AP).
Amel Taha, Norah Alsadun
doaj   +2 more sources

Further interceptions of the Neotropical fungus gnat Sciophila fractinervis Edwards, 1940 (Diptera, Mycetophilidae) in Britain with comments and observations on its biology and spread [PDF]

Biodiversity Data Journal, 2022
From 2020 onwards, several specimens of the Neotropical fungus gnat Sciophila fractinervis (Edwards, 1940) have been intercepted by Fera Science Ltd.
Rob Deady, Mark Delaney, Eleanor Jones, Peter Chandler   +3 more
doaj   +3 more sources

Molecular and cellular response profiles induced by the TLR4 agonist-based adjuvant Glucopyranosyl Lipid A. [PDF]

PLoS ONE, 2012
BACKGROUND: Toll-like receptor (TLR)4 agonists are known potent immunostimulatory compounds. These compounds can be formulated as part of novel adjuvants to enhance vaccine medicated immune responses.
Stacie L Lambert, Chin-Fen Yang, Zheng Liu, Rosemary Sweetwood, Jackie Zhao, Lily Cheng, Hong Jin, Jennifer Woo   +7 more
doaj   +1 more source

A basal level of γ-linolenic acid depletes Ca2+ stores and induces endoplasmic reticulum and oxidative stresses to cause death of breast cancer BT-474 cells

Chinese Journal of Physiology, 2021
Gamma-linolenic acid (GLA), a natural fatty acid obtained from oils of various vegetables and seeds, has been demonstrated as an anticancer agent. In this work, we investigated the anticancer effects of GLA on breast cancer BT-474 cells.
Cing-Yu Chen, Cheng-Hsun Wu, King-Chuen Wu, Lian-Ru Shiao, Chin-Min Chuang, Yuk-Man Leung, Louis W C Chow   +6 more
doaj   +1 more source

Glaucocalyxin A suppresses multiple myeloma progression in vitro and in vivo through inhibiting the activation of STAT3 signaling pathway

Cancer Cell International, 2021
Background Multiple myeloma (MM) is the most common malignant hematological disease in the people worldwide. Glaucocalyxin A (GLA) is a bioactive ent-kauranoid diterpenoid, that is derived from Rabdosia japonica var. GLA has been demonstrated that it had
Mei Li, Cailong Chen, Qian Wang, Xiaolu Jiang, Lanlan Tan, Ying Huang, Yan Zhang, Zubin Zhang   +7 more
doaj   +1 more source

Plasma Globotriaosylsphingosine and α-Galactosidase A Activity as a Combined Screening Biomarker for Fabry Disease in a Large Japanese Cohort

Current Issues in Molecular Biology, 2021
Fabry disease is an X-linked disorder of α-galactosidase A (GLA) deficiency. Our previous interim analysis (1 July 2014 to 31 December 2015) revealed plasma globotriaosylsphingosine as a promising primary screening biomarker for Fabry disease probands ...
Hiroki Maruyama, Atsumi Taguchi, Mariko Mikame, Atsushi Izawa, Naoki Morito, Kazufumi Izaki, Toshiyuki Seto, Akifumi Onishi, Hitoshi Sugiyama, Norio Sakai, Kenji Yamabe, Yukio Yokoyama, Satoshi Yamashita, Hiroshi Satoh, Shigeru Toyoda, Michihiro Hosojima, Yumi Ito, Ryushi Tazawa, Satoshi Ishii   +18 more
doaj   +1 more source

Clinical outcomes in high‐hypoglycaemia‐risk patients with type 2 diabetes switching to insulin glargine 300 U/mL versus a first‐generation basal insulin analogue in the United States : Results from the DELIVER High Risk real‐world study

Endocrinology, Diabetes & Metabolism, 2022
Aims To compare 12‐month clinical effectiveness of insulin glargine 300 units/mL (Gla‐300) versus first‐generation basal insulin analogues (BIAs) (insulin glargine 100 units/mL [Gla‐100] or insulin detemir [IDet]) in patients with type 2 diabetes (T2D ...
Sean D. Sullivan, Nick Freemantle, Rishab A. Gupta, Jasmanda Wu, Charlie J. Nicholls, Jukka Westerbacka, Timothy S. Bailey   +6 more
doaj   +1 more source

Prolonged cognitive dysfunction in patient with splenial lesion of the corpus callosum caused by glufosinate ammonium poisoning

Turkish Journal of Emergency Medicine, 2021
Glufosinate ammonium (GLA) is widely used as a commercial herbicide in many countries. Neurotoxicity of GLA has been associated with serious neurological complications such as loss of consciousness, convulsions, and memory impairment.
Hyun Jung Lee, Jeong Ho Kang
doaj   +1 more source

Sexually Matured Female Mice showed Higher γ-Linolenic Acid (GLA) in the Muscle Tissue

Journal of Animal Reproduction and Biotechnology, 2015
The sexual maturation occurred by the changes of steroid hormones was known to sex-dependently and/or agedependently regulate the lipid metabolism in various animal species.
Chang Seok Park, Sang-Rae Cho, Young Sik Park   +2 more
doaj   +1 more source