Results 121 to 130 of about 148,838 (258)

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

open access: yesAnaesthesia, EarlyView.
Summary Introduction Major lower extremity amputations occurring secondary to vascular disease remain prevalent worldwide. Pain surrounding these procedures is complex, multifactorial and associated with poor functional and psychosocial outcomes. The evidence base informing pain management approaches in major lower extremity amputations remain largely ...
Thanapon Ekkunagul   +81 more
wiley   +1 more source

Implementing transit oriented development in Greater London [PDF]

open access: yes, 2019
This book provides new dimensions and a contemporary focus on sustainable transport, urban regeneration and development in eight countries spanning four continents at different stages of development.
Papa, E., Papa, E.
core  

Label Noise in Pathological Segmentation Is Overlooked, Leading to Potential Overestimation of Artificial Intelligence

open access: yesCancer Science, EarlyView.
This study evaluated how artificial label noise affects cancer pathology segmentation models, demonstrating that boundary‐dependent noise leads to overestimation of performance metrics, while random noise mixtures further harm generalization. Our results highlight the need for standardized noise‐quantification and mitigation methods and for developing ...
Kenji Harada   +4 more
wiley   +1 more source

Optimization ultrasonic-assisted aqueous two-phase extraction of glabridin from licorice root and its activity against the foodborne pathogen MRSA

open access: yesFood Chemistry: X
This study aimed to extract glabridin (GLA) from licorice using an environmentally sustainable ultrasonic-assisted aqueous two-phase extraction method and to evaluate its efficacy.
Qianwei Qu   +13 more
doaj   +1 more source

Diagnostic Accuracy of Deep Learning Models in Detecting Peri‐Implant Marginal Bone Loss: A Systematic Review and Meta‐Analysis

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Background Peri‐implantitis is a common implant complication requiring early detection to prevent bone loss and implant failure. Deep learning models show promise for enhancing radiographic diagnosis. Objectives This review systematically evaluated the diagnostic performance of deep learning models in detecting peri‐implant marginal bone loss ...
Momen A. Atieh   +6 more
wiley   +1 more source

Efficacy and safety of switching basal insulin to insulin glargine 300 U/mL in individuals with inadequately controlled type 2 diabetes on advanced insulin therapies: The Toujeo‐Neo T2DM study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims This real‐world study evaluated the effectiveness and safety of switching basal insulin (BI) to insulin glargine 300 U/mL (Gla‐300) in adults with inadequately controlled type 2 diabetes mellitus (T2DM), previously receiving basal‐supported oral therapy plus prandial insulin (BOTplus) or multiple (≥3) daily injections (MDI) of short ...
Stefan Pscherer   +6 more
wiley   +1 more source

Effects of age and disease duration on the glycaemic outcomes and safety of insulin glargine 300 U/mL in people with type 2 diabetes in China: A post‐hoc analysis of the INITIATION study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate the glycaemic outcomes and safety of insulin glargine 300 U/mL (Gla‐300) in Chinese people with uncontrolled type 2 diabetes (T2D) by baseline age and disease duration. Materials and Methods INITIATION was a 24‐week, interventional, single‐arm study where adults with T2D (glycated haemoglobin [HbA1c] 7.5%–11.0%) received Gla ...
Liming Chen   +12 more
wiley   +1 more source

Flight test technique for evaluation of gust load alleviation analysis methodology [PDF]

open access: yes
A technique for gust load alleviation (GLA) flight testing that will approximate a turbulence-like excitation of the wing has been devised. An artificial excitation is produced by randomly deflecting inboard control surfaces on the wing, thereby ...
Perry, B., III
core   +1 more source

Winter‐active spiders (Clubiona) have a hyperactive antifreeze protein with a unique beta‐solenoid fold

open access: yesThe FEBS Journal, EarlyView.
Antifreeze proteins from winter‐active spiders were purified using their affinity for ice. After LC–MSMS characterization, corresponding transcripts were identified. The antifreeze protein folds as a β‐solenoid with a large flat ice‐binding site on one surface and can bind to ice crystals and prevent their growth at −4 °C.
Laurie A. Graham   +3 more
wiley   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh   +5 more
wiley   +1 more source

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