Results 141 to 150 of about 148,838 (258)

GLA-3 mediates the heat shock response in Caenorhabditis elegans germ cells: A key role for the tristetraprolin (TTP) family. [PDF]

PLoS One
Salinas LS, Dámazo-Hernández ÁA, Cristino-Miranda AM, Zurita-León M, Morales-Oliva E, Láscarez-Lagunas LI, Navarro RE.   +6 more
europepmc   +1 more source

Impact of geriatric impairments on outcomes of single‐agent immunotherapy in solid tumors

International Journal of Cancer, Volume 158, Issue 5, Page 1370-1382, 1 March 2026.
What's New? This study comprehensively assesses the impact of frailty and geriatric impairments on key clinical outcomes of single‐agent immunotherapy in older adults with solid tumors. Using prospective multicenter data, the authors demonstrate that frailty is significantly associated with higher rates of all‐cause hospitalization and mortality ...
Asli Özkan, Karlijn de Joode, Ellen Kapiteijn, Marije Slingerland, Stephanie Zunder, Frederiek van den Bos, Simon Mooijaart, Anna Uit den Boogaard, Stella Trompet, Hans Westgeest, Astrid van der Veldt, Ron H. J. Mathijssen, Geert Labots, Cynthia Holterhues, Els M. E. Verdegaal, Nienke A. de Glas, Johanneke E. A. Portielje   +16 more
wiley   +1 more source

A New Class of Pathogenic Non-Coding Variants in GLA. [PDF]

Int J Mol Sci
Yuan Y, Zhang X, Ling C, Zhao Y, Yu M, Wang Z, Yuan Y, Xie Z, Zhang W.   +8 more
europepmc   +1 more source

A Meta‐Analysis to Unveil the Diagnostic Gaps in Anderson–Fabry Disease in Women

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Anderson–Fabry disease (AFD) is an X‐linked lysosomal storage disorder caused by mutations in the GLA gene, leading to deficient α‐galactosidase A activity. Although historically considered a male disease, it is now recognized that heterozygous women can present with a wide range of symptoms. However, diagnosis in women remains challenging, as
L. Lenzini, G. Pintus, G. Gugelmo, A. P. Burlina, G. P. Fadini, A. B. Burlina, N. Vitturi   +6 more
wiley   +1 more source

Case Report: Diffuse pulmonary lymphangiomatosis in a child. [PDF]

Front Pediatr
Zhang YN, Yuan Z, Du JC, Liu B, Li F, Hu SC, Li QX.   +6 more
europepmc   +1 more source

Profiling and Characterization of Seed Storage Proteins From Borage (Borago officinalis L.) Pressed Cake as a Novel Plant‐Based Protein Source

Sustainable Food Proteins, Volume 4, Issue 1, March 2026.
Borage (Borago officinalis L.) pressed cake, a by‐product of oil extraction, was profiled and characterized to evaluate its potential as a sustainable, plant‐based protein source. Protein fractionation revealed glutelin‐like proteins as predominant, accompanied by 2S albumin, 7S, and 11S globulin‐type proteins. Proteins exhibited high thermal stability
Suneru P. Perera, Rhea Thommana, Dierdre Culbert, Janiko Lindain, Thushan S. Withana‐Gamage   +4 more
wiley   +1 more source

Real-World Effectiveness of Insulin Glargine 300 U/ml in People with Type 2 Diabetes Previously Treated with Tirzepatide: The DELIVER-T Study. [PDF]

Diabetes Ther
Ritzel R, Davies MJ, Hao L, Ji L, Mk L, Mabunay A, Mauricio D, Bailey T.   +7 more
europepmc   +1 more source

A Group Fit Statistic for the Multilevel Item Response Model

Journal of Educational Measurement, Volume 63, Issue 1, Spring 2026.
Abstract Aberrant behaviors among test‐takers in large‐scale assessments are often more prevalent within specific groups or testing sites. While various techniques have been developed to detect individual‐level test‐takers' aberrant behaviors, research in detecting those behaviors at the group level is rare. We propose a group fit statistic lz2$ l_{z2}$
Yishan Ding, Ji Seung Yang, Youngjin Han
wiley   +1 more source

Case Report: Novel GLA mutation in a Chinese female with renal-predominant Fabry disease and cardiac hypertrophy. [PDF]

Front Genet
Li L, Chang T, Li X, Hao Y, Deng M, Li Y.   +5 more
europepmc   +1 more source

Improving Ability Estimation Accuracy for Automated Item Generated Forms under Multistage Testing

Journal of Educational Measurement, Volume 63, Issue 1, Spring 2026.
Abstract The emergence of automated item generation (AIG) techniques has intensified discussions around their application in assessment development. Some testing companies have already begun developing software to construct exams using AIG. However, the current literature offers limited insights into the characteristics of items generated through AIG ...
Stella Y. Kim, Won‐Chan Lee
wiley   +1 more source