Results 1 to 10 of about 1,388 (92)

Subinhibitory concentrations of glabridin from Glycyrrhiza glabra L. reduce Listeria monocytogenes motility and hemolytic activity but do not exhibit antimicrobial activity [PDF]

Frontiers in Microbiology
Increases in the virulence and survival of some pathogens in the presence of subinhibitory concentrations of antibiotics have been reported. However, research on the effects of subinhibitory concentrations of antimicrobial substances derived from ...
Chengshui Liao, Chengshui Liao, Chengshui Liao, Chuan Yu, Jinxiang Guo, Mengxiang Guan   +5 more
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Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo [PDF]

Parasites & Vectors
Background Toxoplasma gondii is an obligate protozoan parasite capable of infecting a wide range of warm-blooded animals and humans. Current treatment options, primarily pyrimethamine and sulfadiazine, have limitations, such as high recurrence rates ...
Lu Wang, Bintao Zhai, Chen Wang, Hany M. Elsheikha, Haiting Guo, Xiao-Nan Zheng, Chun‑Xue Zhou, Xing-Quan Zhu   +7 more
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Exogenous Melatonin Increases Root Yield and Its Medicinal Quality of Glycyrrhiza glabra Under Drought Stress [PDF]

Plants
Glycyrrhiza glabra L. is an economically significant plant that naturally grows in arid regions and is widely used in the cosmetics, food, and pharmaceutical industries. Its roots are the economically important part.
Hui Tian, Minghao Zhou, Miao Ma
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Multi-pathway mechanisms of Liujunzi decoction in promoting glioma apoptosis and reversing drug resistance: network pharmacology and experimental validation [PDF]

Frontiers in Pharmacology
BackgroundGlioma is a highly aggressive brain tumor with a poor prognosis. Recent studies have demonstrated the anti-tumor potential of Liujunzi decoction (LJZD), but its specific effects and mechanisms in glioma remain unclear.
Jinxiang Huang, Jinxiang Huang, Shengnan Lin, Lei Lin, Luning Xu, Dezhi Kang, Dezhi Kang, Dezhi Kang   +7 more
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The antitumor mechanisms of glabridin and drug delivery strategies for enhancing its bioavailability [PDF]

Frontiers in Oncology
Glabridin, a flavonoid derived from the plant Glycyrrhiza glabra, has garnered significant attention due to its diverse pharmacological effects, including antioxidant, antibacterial, anti-inflammatory, hypolipidemic, and hypoglycemic activities.
Chong Li, Yu Wang, Wenjing Zhang, Xiaoman Yang, Yufang Wang, Guanqun Hou, Dongli Wang, Bingbing Han, Yimin Zhang, Yimin Zhang   +9 more
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Licoisoflavone B and glabridin from Glycyrrhiza glabra as potent nucleoprotein antagonists of Lassa virus: insights from molecular docking, dynamics simulation, PCA, and DFT studies [PDF]

Journal of Genetic Engineering and Biotechnology
Lassa virus causes a severe hemorrhagic disease referred to as Lassa fever. It exhibits a significant mortality rate among people in West and Central Africa.
Sk. Faisal Ahmed, Md. Masudur Rahman Munna, Md. Hossain Ahmed, Md. Mostafizur Rahman, Minhajul Islam, Esha Mony Bristy   +5 more
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Regional environmental impacts on growth traits and phytochemical profiles of Glycyrrhiza glabra L. for enhanced medicinal and industrial use [PDF]

BMC Plant Biology
Identifying the optimal cultivation regions and evaluating the impact of environmental factors are crucial for selecting the best conditions for the commercial production of important medicinal and industrial plants.
Ghasem Eghlima, Yasaman Mashhadi Tafreshi, Fateme Aghamir, Hamid Ahadi, Mehrnaz Hatami   +4 more
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Introducing the glycyrrhizic acid and glabridin rich genotypes from the cultivated Iranian licorice (Glycyrrhiza glabra L.) populations to exploit in production systems [PDF]

Scientific Reports
Currently, the stable, uniform, and highly efficient production of raw materials for pharmaceutical companies has received special attention. To meet these criteria and reduce harvesting pressure on the natural habitats of licorice (Glycyrrhiza glabra L.)
Hassan Esmaeili, Mohammad Hossein Mirjalili, Akbar Karami, Samad Nejad Ebrahimi   +3 more
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Self-Assembled pH-Responsive Metal-Organic Frameworks for Enhancing the Encapsulation and Anti-Oxidation and Melanogenesis Inhibition Activities of Glabridin

Molecules, 2022
Metal organic frameworks (MOFs) are formed by self-assembly of metal ions and organic ligands. A special type of MOF called ZIF-8, which is formed by self-assembly of zinc ions and 2-methylimidazole, shows excellent stability in aqueous solutions and ...
Liang Chen, Zexun Liu, Xinying Zhao, Linying Liu, Xiulan Xin, Hao Liang   +5 more
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Glabridin Therapy Reduces Chronic Allodynia, Spinal Microgliosis, and Dendritic Spine Generation by Inhibiting Fractalkine-CX3CR1 Signaling in a Mouse Model of Tibial Fractures

Brain Sciences, 2023
Patients undergoing bone fractures frequently suffer from irritating chronic pain after orthopedic repairs. Chemokine-mediated interactions between neurons and microglia are important steps for neuroinflammation and excitatory synaptic plasticity during ...
Juan Long, Hongbing Liu, Zhimin Qiu, Zhong Xiao, Zhongqiu Lu   +4 more
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