Estrogenicity of glabridin in Ishikawa cells. [PDF]
PLoS ONE, 2015 Glabridin is an isoflavan from licorice root, which is a common component of herbal remedies used for treatment of menopausal symptoms. Past studies have shown that glabridin resulted in favorable outcome similar to 17β-estradiol (17β-E2), suggesting a ...
Melissa Su Wei Poh +3 more
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Molecules, 2022 Metal organic frameworks (MOFs) are formed by self-assembly of metal ions and organic ligands. A special type of MOF called ZIF-8, which is formed by self-assembly of zinc ions and 2-methylimidazole, shows excellent stability in aqueous solutions and ...
Liang Chen +5 more
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The Flavonoid Glabridin Induces OCT4 to Enhance Osteogenetic Potential in Mesenchymal Stem Cells [PDF]
Stem Cells International, 2017 Mesenchymal stem cells (MSCs) are a promising tool for studying intractable diseases. Unfortunately, MSCs can easily undergo cellular senescence during in vitro expansion by losing stemness.
June Seok Heo +2 more
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Licoisoflavone B and glabridin from Glycyrrhiza glabra as potent nucleoprotein antagonists of Lassa virus: insights from molecular docking, dynamics simulation, PCA, and DFT studies. [PDF]
J Genet Eng BiotechnolLassa virus causes a severe hemorrhagic disease referred to as Lassa fever. It exhibits a significant mortality rate among people in West and Central Africa.
Faisal Ahmed S +5 more
europepmc +2 more sources
Selective Extraction of Lipophilic Bioactive Compounds from Industrial Root Meal of Glycyrrhiza glabra L. [PDF]
MoleculesLicorice (Glycyrrhiza glabra L.) root meal generated after industrial extraction of water-soluble constituents represents an underutilized secondary plant resource rich in lipophilic bioactive compounds.
Akbar Sanoev +9 more
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Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo [PDF]
Parasites & VectorsBackground Toxoplasma gondii is an obligate protozoan parasite capable of infecting a wide range of warm-blooded animals and humans. Current treatment options, primarily pyrimethamine and sulfadiazine, have limitations, such as high recurrence rates ...
Lu Wang +7 more
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AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity
Journal of Lipid Research, 2012 In this study, we demonstrate that activation of AMP-activated protein kinase (AMPK) with glabridin alleviates adiposity and hyperlipidemia in obesity.
Joo-Won Lee +12 more
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Glabridin and gymnemic acid alleviates choroid structural change and choriocapillaris impairment in diabetic rat's eyes. [PDF]
World J DiabetesBACKGROUND Small blood vessels in the eyes are more susceptible to injury, which can lead to complications. However, since diabetic retinopathy is often a serious clinical condition, most of this study focuses on the vascular system of the choroid.
Matsathit U +2 more
europepmc +2 more sources
Genetic structure analysis of Glycyrrhiza species and identification of SNP-loci associated with secondary metabolites in G. glabra [PDF]
BMC GenomicsBackground Glycyrrhiza spp. are medicinal legumes that produce a wide array of pharmacologically active secondary metabolites. This study generated a genomic resource by genotyping-by-sequencing 175 Glycyrrhiza accessions and populations to (1 ...
Ali Moghadam +6 more
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Glabridin attenuates LTA‑induced alveolar macrophage migration via activation of the Nrf2/HO‑1 pathway. [PDF]
Mol Med RepOxidative stress and macrophage migration contribute to chronic inflammation and resultant tissue damage. The nuclear factor erythroid 2-related factor 2 (Nrf2) antioxidant pathway plays a key role in maintaining redox balance and modulating immune cell ...
Hsia CH +6 more
europepmc +2 more sources