Results 31 to 40 of about 2,770 (195)

Mechanisms of glabridin inhibition of integrin αIIbβ3 inside-out signals and NF-κB activation in human platelets

Chinese Medicine, 2023
Background Platelets play a crucial role in cardiovascular diseases (CVDs) and are activated by endogenous agonists like collagen. These agonists initiate signal transduction through specific platelet receptors, resulting in platelet aggregation ...
Wei-Chieh Huang, Thanasekaran Jayakumar, Joen-Rong Sheu, Chih-Wei Hsia, Chih-Hsuan Hsia, Ting-Lin Yen, Chao-Chien Chang   +6 more
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Glabridin induces paraptosis-like cell death via ER stress in breast cancer cells

Heliyon, 2022
Glabridin, a polyphenolic flavonoid isolated from the root of the glycyrrhiza glabra, has been demonstrated to have anti-tumor properties in human malignancies. This study found that glabridin decreased the viability of human breast cancer MDA-MB-231 and
Xiang Cui, Min Cui
doaj   +1 more source

The Efficient Activity of Glabridin and its Derivatives Against EGFR-mediated Inhibition of Breast Cancer

, 2023
Background: Breast cancer (BC) is one of the most typical causes of cancer death in women worldwide. Activated epidermal growth factor receptor (EGFR) signaling has been increasingly associated with BC development and resistance to cytotoxic drugs.
Abhijit Dey, Arabinda Ghosh, Zouganelis, G., Gaber El-saber Batiha, Ritika Sharma, Somdatta Yashwant Chaudhari, Padmashree Das, Sonali Arun Waghmare, Athanasios Alexiou, Debanjana Ghosh, Nobendu Mukerjee, Souty M.Z. Sharkawi, Marios Papadakis, Swastika Maitra, Georgios D. Zouganelis   +14 more
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Glabridin From Chinese Herb Licorice Inhibits Fatigue In Mice [PDF]

, 2010
The inhibiting effect of glabridin from Chinese herb Licorice on fatigue was investigated in male BALB/c mice. Mice were divided into the following 4 experimental groups: control group (CG), low dose group (LG), middle dose group (MG) and high dose group
Shang, H, S Cao, Cao, Shehua, J Wang, Putheti, R, Zheng, H, R Putheti, Putheti, Ramesh, Cao, S, Zheng, Hua, Shang, Huaping, Wang, J, H Shang, Wang, Jihui, H Zheng   +14 more
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Synthetic Glabridin Derivatives Inhibit LPS-Induced Inflammation via MAPKs and NF-κB Pathways in RAW264.7 Macrophages

Molecules, 2023
Glabridin is a polyphenolic compound with reported anti-inflammatory and anti-oxidative effects. In the previous study, we synthesized glabridin derivatives—HSG4112, (S)-HSG4112, and HGR4113—based on the structure–activity relationship study of glabridin
Jaejin Shin, Leo Sungwong Choi, Hyun Ju Jeon, Hyeong Min Lee, Sang Hyo Kim, Kwan-Woo Kim, Wonmin Ko, Hyuncheol Oh, Hyung Soon Park   +8 more
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Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra) [PDF]

, 2011
The roots of licorice (Glycyrrhiza glabra) are a rich source of flavonoids, in particular, prenylated flavonoids, such as the isoflavan glabridin and the isoflavene glabrene.
Vincken, J.P., Bovee, T.F.H., Luijendijk, T.J.C., Verbruggen, M.A., The, S.A.M., Mol, L.A.M., Simons, R., Gruppen, H.   +7 more
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Effects of the Licorice Isoflavans Licoricidin and Glabridin on the Growth, Adherence Properties, and Acid Production of Streptococcus mutans, and Assessment of Their Biocompatibility

Antibiotics, 2021
Pharmacological studies have linked a number of human health benefits with licorice due to its anticancer, anti-inflammatory, anti-oxidant, and antimicrobial properties.
Katy Vaillancourt, Geneviève LeBel, Geneviève Pellerin, Amel Ben Lagha, Daniel Grenier   +4 more
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Potentiating effect of glabridin from Glycyrrhiza glabra on GABAA receptors [PDF]

, 2016
Extracts from Glycyrrhiza are traditionally used for the treatment of insomnia and anxiety. Glabridin is one of the main flavonoid compounds from Glycyrrhiza glabra and displays a broad range of biological properties. In the present work, we investigated
Beltrán, Leopoldo, Hoffmann, Katrin M., Ziemba, Paul M., Gisselmann, Günter, Hatt, Hanns   +4 more
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SELECT THE OPTIMAL PRODUCTION WASTE OF MALT ROOTS FOR OBTAINING GLABRIDIN [PDF]

, 2023
Glabridin is the main biologically active phytocomponent of Glycyrrhiza glabra L. Although glabridin is one of the most studied flavonoids in licorice, the main literature is devoted to its biological activity, but there is a lack of data on its ...
A.I. Sanoev, O.T. Juraev, R.M. Khalilov, Sh.Sh. Sagdullaev
core   +1 more source

Effect of Glabridin on Enzymatic Browning of Fresh-Cut Potatoes [PDF]

Shipin Kexue
To elucidate the impact of glabridin on browning in fresh-cut potatoes, the effect of treatment with 100 μmol/L glabridin on the color quality of potato slices was examined.
DENG Mengsheng, SUN Wen’ao, XIE Linghong, OU Tuankui, FENG Liangjie, ZHANG Jie
doaj   +1 more source