Results 31 to 40 of about 2,632 (194)

Absolute configuration of naturally occurring glabridin [PDF]

Acta Crystallographica Section C Crystal Structure Communications, 2013
The title compound {systematic name: 4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol, commonly named glabridin}, C20H20O4, is a species-specific biomarker from the rootsGlycyrrhiza glabraL. (European licorice, Fabaceae).
Charlotte, Simmler, Frank R, Fronczek, Guido F, Pauli, Bernard D, Santarsiero   +3 more
openaire   +2 more sources

Synthetic Glabridin Derivatives Inhibit LPS-Induced Inflammation via MAPKs and NF-κB Pathways in RAW264.7 Macrophages

Molecules, 2023
Glabridin is a polyphenolic compound with reported anti-inflammatory and anti-oxidative effects. In the previous study, we synthesized glabridin derivatives—HSG4112, (S)-HSG4112, and HGR4113—based on the structure–activity relationship study of glabridin
Jaejin Shin, Leo Sungwong Choi, Hyun Ju Jeon, Hyeong Min Lee, Sang Hyo Kim, Kwan-Woo Kim, Wonmin Ko, Hyuncheol Oh, Hyung Soon Park   +8 more
doaj   +1 more source

Effects of the Licorice Isoflavans Licoricidin and Glabridin on the Growth, Adherence Properties, and Acid Production of Streptococcus mutans, and Assessment of Their Biocompatibility

Antibiotics, 2021
Pharmacological studies have linked a number of human health benefits with licorice due to its anticancer, anti-inflammatory, anti-oxidant, and antimicrobial properties.
Katy Vaillancourt, Geneviève LeBel, Geneviève Pellerin, Amel Ben Lagha, Daniel Grenier   +4 more
doaj   +1 more source

KT-939: A Next-Generation Human Tyrosinase Inhibitor With Superior Efficacy for the Safe Management of Hyperpigmentation. [PDF]

J Cosmet Dermatol
ABSTRACT Background Tyrosinase is the rate‐limiting enzyme in melanin biosynthesis, and its overactivity contributes to hyperpigmentation disorders. Existing tyrosinase inhibitors are often limited by poor potency against human tyrosinase (hTYR) or safety concerns. Aims To evaluate the inhibitory potency, safety, and multifunctional activity of KT‐939,
Hou X, Li Y, Zhang Q, Yan H, Zhang X, Yang Y, Cai X, Wang J, Ding M, Chen D, Chen J, Tong Y, Mehta N, Goren A.   +13 more
europepmc   +2 more sources

Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra) [PDF]

, 2011
The roots of licorice (Glycyrrhiza glabra) are a rich source of flavonoids, in particular, prenylated flavonoids, such as the isoflavan glabridin and the isoflavene glabrene.
Bovee, T.F.H., Gruppen, H., Luijendijk, T.J.C., Mol, L.A.M., Simons, R., The, S.A.M., Verbruggen, M.A., Vincken, J.P.   +7 more
core   +2 more sources

Formulation of Liquorice Root Extract (Glycyrrhiza Glabra L.) as Skin Whitening Cream [PDF]

, 2016
Liquorice root extract (Glycyrrhiza glabra L.) contains glabridin, an isoflavane as inhibitors of tyrosinase. This enzyme is responsible in melanin synthesis.
Faridah, F. (Faridah), Michico, M. (Michico), Noor, S. U. (Siti)   +2 more
core   +1 more source

Development and Optimization of Culture Medium for the Production of Glabridin by Aspergillus eucalypticola: An Endophytic Fungus Isolated from Glycyrrhiza glabra L. (Fabaceae)

Mycobiology, 2023
Glabridin is a well-known active isoflavone found in the root of licorice (Glycyrrhiza glabra L.) that possess a wide range of biological activity. Plant cells, hairy roots, and fungal endophytes cultures are the most important alternative methods for ...
Parisa Bahadori Ganjabadi, Mohsen Farzaneh, Mohammad Hossein Mirjalili   +2 more
doaj   +1 more source

Phytochemical composition, health effects and crop management of liquorice (Glycyrrhiza glabra L.): a medicinal plant [PDF]

, 2016
Liquorice has been widely appreciated as an important medicinal plant. Its rhizomes and roots have been used for centuries in traditional medicine due to their renowned therapeutic properties.
Ferreira, Isabel C.F.R., Karkanis, Anestis, Martins, Natália, Petropoulos, Spyridon Α.   +3 more
core   +1 more source

Glavonoid, a possible supplement for prevention of ATTR amyloidosis

Heliyon, 2021
Transthyretin (TTR) is an amyloidogenic protein associated with hereditary and nonhereditary transthyretin amyloidoses (ATTR). Dissociation of the tetramer of TTR to the monomer induces TTR misfolding, which leads to amyloid fibril formation and triggers
Hiroaki Matsushita, Aito Isoguchi, Masamitsu Okada, Teruaki Masuda, Yohei Misumi, Chiharu Tsutsui, Narumi Yamaguchi, Yuko Ichiki, Jinko Sawashita, Mitsuharu Ueda, Mineyuki Mizuguchi, Yukio Ando   +11 more
doaj   +1 more source

Multi-Target Modulation of Polyphenols in Diabetic Kidney Disease Therapeutics: A Comprehensive Review. [PDF]

Food Sci Nutr
This review shows evidence from preclinical and clinical studies, supporting the therapeutic potential of polyphenols for diabetic kidney disease (DKD). This is due to their diverse bioactive properties and ability to intervene in intricate mechanisms of the disease.
Efiong EE, Effa E, Peters E, Erukainure OL, Amadi PU, Ikebuiro JO, Sharma S, Schmaderer C, Maedler K, Tuenter E, Grallert H.   +10 more
europepmc   +2 more sources