Results 51 to 60 of about 2,719 (158)

Establishment of a TaqMan multiplex quantitative PCR method for detecting three different serovars of Glaesserella parasuis serovars 5/12, 7 and 11. [PDF]

BMC Vet Res
Glaesserella parasuis, a commensal in the upper respiratory tract of swine, can cause Glässer’s disease in the stress conditions, which caused great economic loss to the swine industry.
Zhendong W, Hao Y, Lumen C, Yufeng L.
europepmc   +2 more sources

Rab4b Promotes Cytolethal Distending Toxin from <i>Glaesserella parasuis</i>-Induced Cytotoxicity in PK-15 Cells. [PDF]

Toxins (Basel)
Glaesserella parasuis cytolethal distending toxin (GpCDT) can induce cell cycle arrest and apoptosis. Our laboratory’s previous work demonstrated that GTPase 4b (Rab4b) is a key host protein implicated in GpCDT-induced cytotoxicity.
Zhang Y, Yang Z, Dai K, Hu B, Xu S, Wang Y, Lei L, Du S, Zhao Q, Huang X, Wu R, Yan Q, Wang Y, Cao S, Wen Y.   +14 more
europepmc   +2 more sources

TbpB-based oral mucosal vaccine provides heterologous protection against Glässer's disease caused by different serovars of Spanish field isolates of Glaesserella parasuis. [PDF]

Porcine Health Manag
Background Glaesserella parasuis has a substantial impact on the pig production as the primary agent of Glässer’s disease, particularly affecting nursery and early fattening stages.
González-Fernández A, Mencía-Ares O, García-Iglesias MJ, Petrocchi-Rilo M, Miguélez-Pérez R, Perelló-Jiménez A, Herencia-Lagunar E, Acebes-Fernández V, Gutiérrez-Martín CB, Martínez-Martínez S.   +9 more
europepmc   +2 more sources

HbpA from Glaesserella parasuis induces an inflammatory response in 3D4/21 cells by activating the MAPK and NF-κB signalling pathways and protects mice against G. parasuis when used as an immunogen

Veterinary Research
Glaesserella parasuis is usually a benign swine commensal in the upper respiratory tract, but virulent strains can cause systemic infection characterized by pneumonia, meningitis, and fibrinous polyserositis. The intensive pulmonary inflammatory response
Zhen Yang, Yiwen Zhang, Qin Zhao, Senyan Du, Xiaobo Huang, Rui Wu, Qigui Yan, Xinfeng Han, Yiping Wen, San-Jie Cao   +9 more
doaj   +2 more sources

Glaesserella parasuis serotype 4 exploits fibronectin via RlpA for tracheal colonization following porcine circovirus type 2 infection. [PDF]

PLoS Pathog
Porcine circovirus type 2 (PCV2) often causes disease through coinfection with other bacterial pathogens, including Glaesserella parasuis (G. parasuis), which causes high morbidity and mortality, but the role played by PCV2 and bacterial and host factors
Guo M, Li Y, Tang J, Wang Q, Wang Q, Zhou H, Lin H, Ma Z, Fan H.   +8 more
europepmc   +2 more sources

Comparative study of the effects of baicalin and probenecid on microRNA expression profiles in porcine aortic vascular endothelial cells infected by Glaesserella parasuis. [PDF]

BMC Vet Res
Glaesserella parasuis elicits severe inflammatory responses and vascular damage, thus resulting in high mortality and morbidity in pigs; consequently, early diagnosis and treatment are critical to controlling economic losses. MicroRNAs (miRNAs) have been
Guo L, Yang Y, Yang L, Sun P, He J, Fu S, Ye C, Zong B, Qiu Y.   +8 more
europepmc   +2 more sources

Host factor Rab4b mediates internalization and intoxication of 3D4/21 cells by the active subunit of the <i>Glaesserella parasuis</i> cytolethal distending toxin via influencing EEA1 expression. [PDF]

Front Microbiol
Background The cytolethal distending toxin (CDT), a significant exotoxin, is closely linked to the pathogenicity of Glaesserella parasuis (GPS), but its pathogenic not yet fully elucidated.
Zhang Y, Yang Z, Du S, Zhao Q, Huang X, Wu R, Wang Y, Yan Q, Cao S, Wen Y.   +9 more
europepmc   +2 more sources

Design of B-Cell Multi-Epitope Subunit Vaccines Against <i>Glaesserella parasuis</i> by Reverse Vaccinology: An In Silico and In Vivo Study. [PDF]

Transbound Emerg Dis
Glässer’s disease caused by Glaesserella parasuis (GPS) is a severe disease that results in substantial economic losses to the swine industry worldwide. Here we describe a multiepitope vaccine cocktail (MEVC) that was designed using reverse vaccinology and immunoinformatics. The MEVC was comprised of three multiepitope subunits (MESs, designated as TB,
Gong Y, Li N, Li Z, Wang H, Zhang D, Chu H, Lu Z, Jia A, Li F, Lei L.   +9 more
europepmc   +2 more sources

Deletion of two-component system QseBC weakened virulence of Glaesserella parasuis in a murine acute infection model and adhesion to host cells [PDF]

PeerJ, 2022
The widespread two-component system (TCS), QseBC, involves vital virulence regulators in Enterobacteriaceae and Pasteurellaceae. Here we studied the function of QseBC in Glaesserella parasuis. A ΔqseBC mutant was constructed using a Glaesserella parasuis
Xuefeng Yan, Ke Dai, Congwei Gu, Zehui Yu, Manli He, Wudian Xiao, Mingde Zhao, Lvqin He   +7 more
doaj   +2 more sources

Transcriptomic differences noted in Glaesserella parasuis between growth in broth and on agar.

PLoS ONE, 2019
Glaesserella parasuis is the cause of Glӓsser's disease in pigs and is a significant contributor to post-weaning mortality in the swine industry. Prevention of G.
Samantha J Hau, Kathy T Mou, Darrell O Bayles, Susan L Brockmeier   +3 more
doaj   +4 more sources