Results 61 to 70 of about 262,302 (346)
Neuropathobiology of COVID-19: The Role for Glia
Frontiers in Cellular Neuroscience, 2020 SARS-CoV-2, which causes the Coronavirus Disease 2019 (COVID-19) pandemic, has a brain neurotropism through binding to the receptor angiotensin-converting enzyme 2 expressed by neurones and glial cells, including astrocytes and microglia.
M. Tremblay +4 more
semanticscholar +1 more source
Mathematical model of brain tumour with glia-neuron interactions and chemotherapy treatment [PDF]
, 2015 Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: Fundação Araucária, EPSRC-EP/I032606/1 and CNPq, CAPES and Science Without Borders Program Process nos. 17656125, 99999.010583/2013-00
Baptista, Murilo Da Silva +7 more
core +1 more source
The Role of Gut Mucins in the Etiology of Depression
Frontiers in Behavioral Neuroscience, 2020 Major depressive disorders are global health problems that affect more than 6% of the U.S. population. Despite years of research, the etiology of depression remains unclear. Historically, it was believed that depression started within the central nervous
Courtney Rivet-Noor +3 more
doaj +1 more source
Satellite glia modulate sympathetic neuron survival, activity, and autonomic function
eLife, 2022 Satellite glia are the major glial cells in sympathetic ganglia, enveloping neuronal cell bodies. Despite this intimate association, the extent to which sympathetic functions are influenced by satellite glia in vivo remains unclear.
Aurelia A Mapps +10 more
doaj +1 more source
Cerebellar Cortex, Purkinje Cell Layer [PDF]
, 2008 This report contains a summary of expression patterns for genes that are enriched in the Purkinje cell layer (CBXpu) of the cerebellum. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science +3 more
core +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Neurobiology of Disease, 2023 The neurovascular unit (NVU) plays a critical role in health and disease. In the current review, we discuss the critical role of a class of neural/glial antigen 2 (NG2)-expressing glial cells (NG2-glia) in regulating NVU after acute ischemic stroke (AIS).
Xiaoyan Hu +7 more
doaj +1 more source
Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. [PDF]
, 2014 Autism spectrum disorders (ASDs) are complex and heterogeneous developmental disabilities affecting an ever-increasing number of children worldwide. The diverse manifestations and complex, largely genetic aetiology of ASDs pose a major challenge to the ...
Adamopoulos, Iannis E +9 more
core +2 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Scientific Reports, 2017 Age-related macular degeneration (AMD), a leading contributor of vision loss, currently lacks comprehensive treatment. While AMD histopathology involves retinal pigment epithelium (RPE) injury associated with immune cell infiltration, the nature of ...
Wenxin Ma +5 more
doaj +1 more source