Case Reports in Neurology, 2012 Adult-onset Alexander disease (AOAD) has been increasingly recognized since the identification of the glial fibrillary acidic protein gene mutation in 2001.
Tadahiro Yonezu +5 more
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Glial reaction in the hippocampus after global cardiogenic ischemia [PDF]
, 2001 Many experimental surgerical procedures have been perfomed in the analyse of the phenomenon of brain trophism and plasticity, however undesirable intercorrence can occour leading to specific changes in the results that should be taken into attention.
Chadi, Gerson, Martins, Emerson Fachin
core +3 more sources
BMC Neurology, 2023 Background Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a recently identified recurrent meningoencephalomyelitis with GFAP immunoglobulin G presence in the serum or cerebrospinal fluid (CSF) as a specific biomarker.
Ke Li, Jingwei Wu, Junwu Chen, Yong You
doaj +1 more source
Glial Fibrillary Acidic Protein Astrocytopathy in Pediatric Patients: A Retrospective Study
Frontiers in Pediatrics, 2021 Autoimmune glial fibrillary acidic protein astrocytopathy is a novel form of autoimmune meningoencephalitis related to GFAP autoantibodies. This condition is still being characterized, and few pediatric patients have been identified.
Haixia Huang +13 more
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Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]
, 2018 Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro +8 more
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Teaching NeuroImages: Autoimmune glial fibrillary acidic protein meningoencephalomyelitis [PDF]
Neurology, 2019 A 73-year-old woman with myelodysplastic syndrome presented with 2 months of decline in cognition and mobility, accompanied by headache and weight loss. Examination revealed a somnolent woman with symmetric cogwheel rigidity, bradykinesia, arm myoclonus, and hyperreflexia.
Paula K J, Lee +2 more
openaire +2 more sources
Nociceptive neuropeptide increases and periorbital allodynia in a model of traumatic brain injury. [PDF]
, 2012 OBJECTIVE: This study tests the hypothesis that injury to the somatosensory cortex is associated with periorbital allodynia and increases in nociceptive neuropeptides in the brainstem in a mouse model of controlled cortical impact (CCI) injury.
Amenta, Peter S. +4 more
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Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]
, 2020 Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B. +11 more
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Autoimmune glial fibrillary acidic protein astrocytopathy in children: a retrospective study
European Journal of Medical Research, 2022 Objective To describe the clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy in children. Method Data from 11 pediatric patients with autoimmune GFAP astrocytopathy were retrospectively analyzed.
Xiamei Zhuang +3 more
doaj +1 more source
Activation of Egr-1 expression in astrocytes by HIV-1 Tat: new insights into astrocyte-mediated Tat neurotoxicity [PDF]
, 2011 Human immunodeficiency virus type 1 (HIV-1) Tat plays an important role in HIV-associated neuropathogenesis; the underlying mechanisms are still evolving. We have recently shown that HIV-1 Tat induces expression of glial fibrillary acidic protein (GFAP),
Fan, Yan +4 more
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