Results 91 to 100 of about 82,505 (300)

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Case Report: Cerebrospinal fluid eosinophilia in adult autoimmune GFAP astrocytopathy

Frontiers in Immunology
A 30-year-old Chinese male diagnosed with autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy presented with cerebrospinal fluid (CSF) eosinophilia.
Yuting Hou, Chunmei Zhao, Xu Wang
doaj   +1 more source

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway [PDF]

, 2012
Peer reviewedPublisher ...
Berg, Daniela, Fleckenstein, Corinna, Itohara, Shigeyoshi, Lang, Johannes, Maetzler, Walter, Martin, Heather Louise, Mounsey, Ross Brian, Mustafa, Sarah, Sathe, Kinnari, Schulte, Claudia, Synofzik, Matthis, Teismann, Peter, Vukovic, Zvonimir   +12 more
core   +1 more source

Magnetically Responsive Piezoelectric Nanocapacitors Enhance Neural Recovery Following Spinal Cord Injury via Targeted Spinal Magnetic Stimulation

Advanced Science, EarlyView.
This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao, Tingting Li, Lechi Zhang, Chunya Xia, Zelin Su, Xuyan Ren, Yingjie Fan, Zerui Wu, Yaobo Liu, Min Su   +9 more
wiley   +1 more source

Modelling the injured spinal cord using 3-dimensional cell cultures; strategies for improving tissue engineered repair [PDF]

, 2007
not ...
East, E., Golding, J. P., Phillips, J. B.   +2 more
core  

Label‐Free Molecular Characterization of Protein Aggregates in Differentiated Astrocytes

Advanced Science, EarlyView.
Mid‐infrared photothermal microscopy enables label‐free structural, molecular, and functional imaging of protein aggregates in astrocyte cells. The processes of astrocytes differentiated on a nanomaterial interface are characterized by α‐helical signatures combined with enhanced interfacial thermal resistance properties, while the cell soma of non ...
Panagis D. Samolis, Chiara Lazzarini, Rahmetullah Durgun, Barbara Barile, Giorgia Conte, Tamara Posati, Marco Caprini, Grazia Paola Nicchia, Valentina Benfenati, Michelle Y. Sander   +9 more
wiley   +1 more source

A MicroRNA124 Target Sequence Restores Astrocyte Specificity of gfaABC1D-Driven Transgene Expression in AAV-Mediated Gene Transfer

Molecular Therapy: Nucleic Acids, 2017
Experimentally restricting transgene expression exclusively to astrocytes has proven difficult. Using adeno-associated-virus-mediated gene transfer, we assessed two commonly used glial fibrillary acidic protein promoters: the full-length version gfa2 (2 ...
Grit Taschenberger, Julia Tereshchenko, Sebastian Kügler   +2 more
doaj   +1 more source

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment. [PDF]

, 2018
Increasing evidence points to an important role for neutrophils in participating in the pathogenesis of the human demyelinating disease MS and the animal model EAE.
Doty, Daniel J, Fujinami, Robert S, Grist, Jonathan J, Lane, Thomas E, Marro, Brett S, Skinner, Dominic D, Syage, Amber R, Worne, Colleen   +7 more
core   +1 more source

Neuroprotective Effects of Time‐Restricted Feeding Combined With Different Protein Sources in MPTP‐Induced Parkinson's Disease Mice Model and Its Modulatory Impact on Gut Microbiota Metabolism

Advanced Science, EarlyView.
Time‐restricted feeding (TRF) exerts protein‐dependent neuroprotective effects in an MPTP‐induced Parkinson's disease model. In casein‐fed mice, TRF improves gut barrier integrity and reduces neuroinflammation, possibly via modulation of Allobaculum and BCAAs.
Ting Li, Jian Wu, Sheng‐Yang Zhou, Ming‐An Li, Li‐Ping Zhao, Ao Wang, Yi‐Zhi Song, Wen‐Yan Huang, Lu‐Lu Tan, Chen‐Meng Qiao, Wei‐Jiang Zhao, Chun Cui, Yan‐Qin Shen   +12 more
wiley   +1 more source

Isolation and characterization of neural crest progenitors from adult dorsal root ganglia [PDF]

, 2007
After peripheral nerve injury, the number of sensory neurons in the adult dorsal root ganglia (DRG) is initially reduced but recovers to a normal level several months later. The mechanisms underlying the neuronal recovery after injury are not clear. Here,
Abrous, Ballas, Bedford, Belmadani, Berg, Bixby, Bondurand, Campos, Cecchini, Cheung, Chie, Ciaroni, Corti, Cosgaya, Crane, Devor, Elson, Eng, Evonne Hwee Min Say, Farel, Farel, Farinas, Fernandes, Greenwood, Grothe, Groves, Groves, Groves, Hagedorn, Hong-Yun Li, Hu, Iwashita, Jessen, Kleber, Kruger, Kruger, Kuo, La Forte, Le Douarin, Lee, Lendahl, Lindsay, Lo, Lopez, Ma, Marmigere, Maro, Ming, Mohammed, Molofsky, Mori, Morrison, Murphy, Namaka, Okano, Popken, Pover, Rask-Andersen, Real, Sauka-Spengler, Sommer, Stemple, Steventon, Stewart, Svenningsen, Tomita, Tucker, Valero, Wiggins, Wong, Xian, Xin-Fu Zhou, Yamashita, Yoon, Young, Yun, Zhou, Zhou   +77 more
core   +1 more source