Results 91 to 100 of about 32,747 (256)
Journal of Advanced Pharmaceutical Technology & Research, 2018 Studies have shown that about 65% of diabetics have hypertension. Treatment for diabetic patients with hypertension is usually given a combination of drugs such as amlodipine (AML) and glibenclamide (GLI).
Febrina Amelia Saputri +9 more
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Effects of glibenclamide on memory retention of passive avoidance learning in rats
The Journal of Qazvin University of Medical Sciences, 2017 Background: Glucose increases memory in rats, and inhibit memory impairments produced by morphine. One mechanism by which glucose might act on memory via regulating the ATP-sensitive potassium channel.
MH. Esmaeili +4 more
doaj
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundWe previously have shown that glibenclamide (GBC), a sulfonylurea receptor 1–transient receptor potential M4 (SUR1‐TRPM4) channel inhibitor, improves survival and neurological outcome after asphyxial cardiac arrest and cardiopulmonary ...
Kaibin Huang +9 more
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Glibenclamide for the Treatment of Acute CNS Injury
Pharmaceuticals, 2013 First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic KATP ...
J. Marc Simard +6 more
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Glibenclamide enhances neurogenesis and improves long-term functional recovery after transient focal cerebral ischemia [PDF]
, 2013 Glibenclamide is neuroprotective against cerebral ischemia in rats. We studied whether glibenclamide enhances long-term brain repair and improves behavioral recovery after stroke.
Jolkkonen, Jukka +3 more
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ATP-Sensitive Potassium Channel-Mediated Lactate Effect on Orexin Neurons: Implications for Brain Energetics during Arousal [PDF]
, 2010 Active neurons have a high demand for energy substrate, which is thought to be mainly supplied as lactate by astrocytes. Heavy lactate dependence of neuronal activity suggests that there may be a mechanism that detects and controls lactate levels and/or ...
Hirasawa, Michiru, Parsons, Matthew P.
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Glibenclamide pretreatment attenuates early hematoma expansion of warfarin-associated intracerebral hemorrhage in rats by alleviating perihematomal blood–brain barrier dysfunction [PDF]
, 2023 Zongwei Zeng +8 more
openalex +1 more source
Extrapancreatic insulin effect of glibenclamide [PDF]
, 1991 In eight patients with uncomplicated non insulin dependent diabetes mellitus, serum insulin levels, serum C-peptide levels and blood glucose levels were measured before and after oral administration of glibenclamide 0.1 mg/kg body weight and a test meal,
Lely, A-J. (Aart-Jan) van der +2 more
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Сахарный диабетBACKGROUND: In the treatment of diabetes mellitus (DM) for a persistent reduction in blood glucose levels it was widely used glibenclamide — a KATP channels blocker. However, its effects on cerebral circulation have been studied very little.
I. B. Sokolova, G. I. Lobov
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Management of diabetes from preconception to the postnatal period: summary of NICE guidance [PDF]
, 2008 Diabetes in pregnancy is associated with risks to the woman (for example, higher rates of miscarriage, preeclampsia, and preterm labour) and to the developing fetus and baby (for example, higher rates of congenital malformations, macrosomia, birth ...
Guideline Development Group, NICE +1 more
core +3 more sources