Results 81 to 90 of about 19,031 (203)
Effect of P-glycoprotein inhibition on glibenclamide concentrations.
, 2015 (A) Individual glibenclamide concentrations in plasma of rats injected intraperitoneally with 50mg/kg glibenclamide in the presence of elacridar (n = 11; grey bars) or vehicle (n = 10; black bars).
Carolina Lahmann (777432) +2 more
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Glibenclamide for the Treatment of Acute CNS Injury
Pharmaceuticals, 2013 First introduced into clinical practice in 1969, glibenclamide (US adopted name, glyburide) is known best for its use in the treatment of diabetes mellitus type 2, where it is used to promote the release of insulin by blocking pancreatic KATP ...
J. Marc Simard +6 more
doaj +1 more source
Glibenclamide treatment prevents the development of diabetes in NOD mice.
, 2016 a) All mice had normal blood glucose levels at week 5. Thereafter, the proportion of untreated animals, which remained normoglycaemic, rapidly dropped with time (open symbols).
Helena Pontes (148291) +5 more
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Background No treatment is available to prevent brain oedema, which can occur after a large hemispheric infarction. Glibenclamide has previously been shown to improve functional outcome and reduce neurological or oedema-related death in patients younger ...
Collins, J +15 more
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Glibenclamide decelerates the responses of coronary regulation in the goat
, 1994 The role of blocking ATP-sensitive potassium (KATP) channels by glibenclamide on the dynamic responses of coronary resistance to abrupt changes in perfusion pressure and heart rate was investigated.
Dankelman, J. +2 more
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Solubility Enhancement of Antidiabetic Drug: Glibenclamide [PDF]
, 2015 INTRODUCTION: As a result of the modern ‘high throughput’ approach to drug discovery, it has been estimated that up to 70% of the new chemical entities(NCEs) entering drug development possess insufficient aqueous solubility to allow adequate and ...
Madhankumar, K
core
Trend 1 as depicted by Sandoz Glibenclamide.
, 2019 Trend 1 as depicted by Sandoz Glibenclamide.
Fatima Suleman (4118119) +1 more
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Сахарный диабетBACKGROUND: In the treatment of diabetes mellitus (DM) for a persistent reduction in blood glucose levels it was widely used glibenclamide — a KATP channels blocker. However, its effects on cerebral circulation have been studied very little.
I. B. Sokolova, G. I. Lobov
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PREPARATION AND EVALUATION OF POLYMERIC NANOPARTICLES OF GLIBENCLAMIDE
, 2014 Simple, reliable and reproducible method was used for the preparation of polymeric nanoparticles of Glibenclamide. The formulation was prepared by solvent evaporation method using magnetic stirrer with overnight stirring and the same was then evaluated ...
Naha, Anup +5 more
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Internalization of 3H-glibenclamide in pancreatic islet cells [PDF]
, 1986 As judged by autoradiographic criteria at the optical level, rat islet cells progressively accumulate 3H-glibenclamide over 1 to 30 min incubation at 24°C.
Sawano, F +3 more
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