Results 71 to 80 of about 21,237 (199)
Fig leaves represent an underutilized source of bioactive compounds and promising functional ingredients. Emerging extraction technologies offer powerful tools to unlock their potential through sustainable and circular valorization, while addressing key safety and regulatory considerations.
Tamara Cilia Attard +4 more
wiley +1 more source
A number of dysfunctions of congenital and adaptive components of the immune system are observed in progeny of rats with experimental gestational diabetes (EGD).
Т. М. Prozorova +2 more
doaj +1 more source
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid +4 more
wiley +1 more source
Glibenclamide-treated diploids and their haploid mitotic segregants.
(a) Mitotic segregant (arrow) derived from the UT448//A757 diploid strain growing in the absence of glibenclamide. (b) Origin of the glibenclamide-treated diploids (arrows) in plates containing MM + 10 μM glibenclamide.
Juliane Rocha de Sant’Anna (710502) +3 more
core +1 more source
ABSTRACT Gestational diabetes mellitus (GDM) represents far more than a transient glycaemic disorder: it is a sentinel metabolic event that unveils pre‐existing defects in β‐cell function and insulin action, with profound implications for both maternal and offspring cardiometabolic health across the lifespan.
Mustafa Kanat +2 more
wiley +1 more source
A Protective Role of Glibenclamide in Inflammation-Associated Injury
Glibenclamide is the most widely used sulfonylurea drug for the treatment of type 2 diabetes mellitus (DM). Recent studies have suggested that glibenclamide reduced adverse neuroinflammation and improved behavioral outcomes following central nervous ...
Gensheng Zhang +5 more
doaj +1 more source
Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
ATP-sensitive potassium (KATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic β-cells to maintain glucose homeostasis.
Gregory M Martin +7 more
doaj +1 more source
Virendra Rambiritch,1 Poobalan Naidoo,2 Breminand Maharaj,1 Goonaseelan Pillai3 1University of KwaZulu-Natal, Durban, 2Department of Internal Medicine, RK Khan Regional Hospital, Chatsworth, South Africa; 3Novartis Pharma AG, Basel, Switzerland Aim:
Naidoo P +3 more
core
Effects of glibenclamide on memory retention of passive avoidance learning in rats
Background: Glucose increases memory in rats, and inhibit memory impairments produced by morphine. One mechanism by which glucose might act on memory via regulating the ATP-sensitive potassium channel.
MH. Esmaeili +4 more
doaj
Hong Chen,1,2 Yongjie Ding,1,2 Wei Chen,1,2 Yun Feng,1,2 Guochao Shi1,21Department of Respiration and Critical Care Disease, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 20025, People’s Republic of China; 2Institute ...
Ding Y, Feng Y, Chen W, Shi G, Chen H
core

