Results 71 to 80 of about 21,237 (199)

Exploring the Potential of Fig Leaves (Ficus carica L.): A Review of Their Valorization as Valuable Bioresources

open access: yesFood Frontiers, Volume 7, Issue 5, September 2026.
Fig leaves represent an underutilized source of bioactive compounds and promising functional ingredients. Emerging extraction technologies offer powerful tools to unlock their potential through sustainable and circular valorization, while addressing key safety and regulatory considerations.
Tamara Cilia Attard   +4 more
wiley   +1 more source

Effect of experimental gestational diabetes and administration of glibenclamide on mRNA level of NLRP3-inflammasome and distribution of NLRP3+-cells in mesenteric lymph nodes in progeny

open access: yesPatologìâ, 2017
A number of dysfunctions of congenital and adaptive components of the immune system are observed in progeny of rats with experimental gestational diabetes (EGD).
Т. М. Prozorova   +2 more
doaj   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid   +4 more
wiley   +1 more source

Glibenclamide-treated diploids and their haploid mitotic segregants.

open access: yes, 2015
(a) Mitotic segregant (arrow) derived from the UT448//A757 diploid strain growing in the absence of glibenclamide. (b) Origin of the glibenclamide-treated diploids (arrows) in plates containing MM + 10 μM glibenclamide.
Juliane Rocha de Sant’Anna (710502)   +3 more
core   +1 more source

How the First 9 Months Shape the Rest of Your Life: The Impact of Gestational Diabetes on the Metabolic Future

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 7705-7718, September 2026.
ABSTRACT Gestational diabetes mellitus (GDM) represents far more than a transient glycaemic disorder: it is a sentinel metabolic event that unveils pre‐existing defects in β‐cell function and insulin action, with profound implications for both maternal and offspring cardiometabolic health across the lifespan.
Mustafa Kanat   +2 more
wiley   +1 more source

A Protective Role of Glibenclamide in Inflammation-Associated Injury

open access: yesMediators of Inflammation, 2017
Glibenclamide is the most widely used sulfonylurea drug for the treatment of type 2 diabetes mellitus (DM). Recent studies have suggested that glibenclamide reduced adverse neuroinflammation and improved behavioral outcomes following central nervous ...
Gensheng Zhang   +5 more
doaj   +1 more source

Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM

open access: yeseLife, 2019
ATP-sensitive potassium (KATP) channels composed of a pore-forming Kir6.2 potassium channel and a regulatory ABC transporter sulfonylurea receptor 1 (SUR1) regulate insulin secretion in pancreatic β-cells to maintain glucose homeostasis.
Gregory M Martin   +7 more
doaj   +1 more source

Population pharmacokinetic modeling of glibenclamide in poorly controlled South African type 2 diabetic subjects

open access: yes, 2016
Virendra Rambiritch,1 Poobalan Naidoo,2 Breminand Maharaj,1 Goonaseelan Pillai3 1University of KwaZulu-Natal, Durban, 2Department of Internal Medicine, RK Khan Regional Hospital, Chatsworth, South Africa; 3Novartis Pharma AG, Basel, Switzerland Aim:
Naidoo P   +3 more
core  

Effects of glibenclamide on memory retention of passive avoidance learning in rats

open access: yesThe Journal of Qazvin University of Medical Sciences, 2017
Background: Glucose increases memory in rats, and inhibit memory impairments produced by morphine. One mechanism by which glucose might act on memory via regulating the ATP-sensitive potassium channel.
MH. Esmaeili   +4 more
doaj  

Glibenclamide alleviates inflammation in oleic acid model of acute lung injury through NLRP3 inflammasome signaling pathway

open access: yes, 2019
Hong Chen,1,2 Yongjie Ding,1,2 Wei Chen,1,2 Yun Feng,1,2 Guochao Shi1,21Department of Respiration and Critical Care Disease, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 20025, People’s Republic of China; 2Institute ...
Ding Y, Feng Y, Chen W, Shi G, Chen H
core  

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