Results 51 to 60 of about 19,031 (203)

Pharmacological and Phytochemical Insights Into Ficus benghalensis (Indian Banyan): Anti‐Inflammatory, Antioxidant, and Anticancer Potentials

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
The aim of this review is to critically evaluate the therapeutic potential of Ficus benghalensis L. by integrating ethnomedicinal knowledge with contemporary scientific evidence. The objectives are to summarize its phytochemical profile, analyze antioxidant, antimicrobial, antidiabetic, anti‐inflammatory, and anticancer activities, elucidate underlying
Zainab Ali, Farhang Hameed Awlqadr, Uswa Ali, Iffat Ullah, Muhammad Tayyab Arshad, Abdul Rauf, Humaira Parveen, Sayeed Mukhtar, Uzma Faridi, Md. Sakhawot Hossain   +9 more
wiley   +1 more source

Comparative Study of Palm Leaves Extract and Glibenclamide in diabetic female rats induced by alloxan [PDF]

Mirror of Research in Veterinary Sciences and Animals, 2013
This study was designed to compare the effect of palm leaves extract and glibenclamide in diabetic female rats induced by alloxan. Twenty four adult female rats were randomly divided into four equal groups (6 rats in each group), three groups were ...
Nabeel M. N. Al-Sharafi Nadia K. J. Al-Dawah, Nadia K. J. Al-Dawah   +1 more
doaj   +1 more source

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

British Journal of Pharmacology, Volume 183, Issue 12, Page 3213-3233, June 2026.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud, Eleonora Malerba, Simona Drago, Antonella Orlando, Domenica Mallardi, Nicoletta De Lucia, Marina Antonacci, Annamaria Di Turi, Domenico Tricarico, Francesco Russo   +9 more
wiley   +1 more source

Glibenclamide quantification after intracranioventricular drug delivery.

, 2015
(A) Representative photograph of Nissl stained coronal section from a chronically ICV implanted rat (Scale bar: 500μm). (B) Glibenclamide concentrations in plasma (black circles) and CSF (grey circles) of rats given vehicle (n = 4) or glibenclamide (n ...
Carolina Lahmann (777432), Frances M. Ashcroft (106321), Holger B. Kramer (221354)   +2 more
core   +1 more source

The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye, Ibi Erekosima, Adrian H. Heald, Gesiye Bozimo, Simon G. Anderson, Samuel Seidu, Kariba Akhidue, Adaeze Ugwu, Chioma Unachukwu, Ibitrokoemi Korubo, Kingsley Chukwuemeka Patrick‐Iwuanyanwu, Victoria Gomba, Uwoma Batubo, Victoria Akanatei, Victor Ken‐Uba, Iyeopu Siminialayi, Sokiprim Akoko, Justin Ideozu, Hamilton Opurum   +18 more
wiley   +1 more source

Glibenclamide, a Sur1-Trpm4 antagonist, does not improve outcome after collagenase-induced intracerebral hemorrhage.

PLoS ONE, 2019
The sulfonylurea 1 transient receptor potential melastatin 4 (Sur1-Trpm4) receptor is selectively expressed after intracerebral hemorrhage (ICH). This upregulation contributes to increases in intracellular sodium.
Cassandra M Wilkinson, Paul S Brar, Celine J Balay, Frederick Colbourne   +3 more
doaj   +1 more source

Glibenclamide Reduces Primary Human Monocyte Functions Against Tuberculosis Infection by Enhancing M2 Polarization

Frontiers in Immunology, 2018
Tuberculosis (TB) is a global public health problem, which is caused by Mycobacterium tuberculosis (Mtb). Type 2 diabetes mellitus (T2DM) is one of the leading predisposing factors for development of TB after HIV/AIDS. Glibenclamide is a widely used anti-
Chidchamai Kewcharoenwong, Chidchamai Kewcharoenwong, Satria A. Prabowo, Satria A. Prabowo, Gregory J. Bancroft, Gregory J. Bancroft, Helen A. Fletcher, Helen A. Fletcher, Ganjana Lertmemongkolchai, Ganjana Lertmemongkolchai   +9 more
doaj   +1 more source

Maternal‐to‐Infant Transfer of Medications for Type 2 Diabetes Mellitus Via Breastmilk: A Systematic Review of Available Evidence and Clinical Guidelines

Clinical Pharmacology &Therapeutics, Volume 119, Issue 5, Page 1223-1234, May 2026.
This review evaluates the available pharmacokinetic data on the plasma‐to‐breastmilk transfer of first‐ and second‐line T2DM drugs against available clinical guideline recommendations. A list of drug therapies for treating T2DM was generated from national and international clinical guidelines.
Katherine Richardson, Joshua Kiptoo, Beatrice Mpora Odongkara, Francis Williams Ojara, Catriona Waitt   +4 more
wiley   +1 more source

Effect of pellet drug dose on plasma glibenclamide concentration.

, 2015
(A) Glibenclamide concentration in plasma from individual male mice implanted with a vehicle (n = 15 animals), a 0.25mg glibenclamide (n = 5 animals), a 2.5mg glibenclamide (n = 7 animals) or a 25mg glibenclamide pellet (n = 5 animals). (B) Glibenclamide
Carolina Lahmann (777432), Frances M. Ashcroft (106321), Holger B. Kramer (221354)   +2 more
core   +1 more source

Haemostasiologic effects of various glucose-lowering medications in type 2 diabetes mellitus

Кардиоваскулярная терапия и профилактика, 2010
Aim. To evaluate the effects of insulin and other glucose-lowering medications on platelet function and coagulation haemostasis in patients with Type 2 diabetes mellitus (DM-2). Material and methods.
G. G. Petrik, S. A. Pavlishchuk
doaj