Results 41 to 50 of about 21,237 (199)
, 2014 The development of chronic kidney disease (CKD) and associated cardiovascular disease involves free radical damage and inflammation. Addition of adenine to the diet induces inflammation followed by CKD and cardiovascular disease.
Diwan, Vishal +2 more
core +1 more source
Pharmacokinetic of Diclofenac in the Presence and Absence of Glibenclamide in the Rat
Journal of Pharmacy & Pharmaceutical Sciences, 2009 - PURPOSE. There is evidence that the sulfonylurea antidiabetic agent glibenclamide reduces the analgesic action of non-steroidal anti-inflammatory drugs (NSAIDs), opioids and neuromodulators in animal models. Therefore, in view of the vast clinical uses
María R. León-Reyes +2 more
doaj +1 more source
JSFA reports, EarlyView.Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed +5 more
wiley +1 more source
Notulae Scientia Biologicae, 2022 This study investigated Stereospermum kunthianum stem bark hydromethanol extract for hypoglycemic and in vitro antioxidant activities. Phytochemical analyses were performed to determine the components of the extract.
Julius O. ODE +8 more
doaj +1 more source
Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges
Neuroprotection, EarlyView.Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi +5 more
wiley +1 more source
Plasma glibenclamide concentrations.
, 2015 (A) Glibenclamide concentration in plasma from individual female (white bars) and male (grey bars) mice implanted with a 21-day slow release 2.5mg glibenclamide pellet or a vehicle pellet. Data are mean±SEM of triplicate measurements.
Carolina Lahmann (777432) +2 more
core +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Pharmaceuticals, 2022 Successful drug delivery by mucoadhesive systems depends on the polymer type, which usually gets adherent on hydration. The intended polymers must sustain the association with biomembranes and preserve or accommodate the drug for an extended time.
Waleed Y. Rizg +12 more
doaj +1 more source
International Journal of Biological Sciences, 2011 Diabetes mellitus is associated with deterioration of glycemic control and progressive metabolic derangements. This study investigated the effect of honey as an adjunct to glibenclamide or metformin on glycemic control in streptozotocin-induced diabetic ...
Omotayo Owomofoyon Erejuwa, Siti Amrah Sulaiman, Mohd Suhaimi Ab Wahab, Kuttulebbai Nainamohammed Salam Sirajudeen, Md Salzihan Md Salleh, Sunil Gurtu
doaj
THERAPEUTIC EFFICACY OF ZINC OXIDE NANOPARTICLES IN DIABETIC RATS
Slovenian Veterinary Research, 2019 This study attempted to scrutinize the potential efficacy of zinc oxide nanoparticles (ZnONPs) and the standard oral hypoglycemic drug glibenclamide in streptozotocin (STZ) -nicotinamide induced diabetic rats.
Mohamed Kamel +3 more
doaj +1 more source