Results 91 to 100 of about 222,357 (321)
Locomotion and proliferation of glioblastoma cells in vitro: statistical evaluation of videomicroscopic observations [PDF]
arXiv, 1999 Long-term videomicroscopy and computer-aided statistical analysis were used to determine some characteristic parameters of in vitro cell motility and proliferation in three established cell lines derived from human glioblastoma tumors. Migration and proliferation activities were compared among the three cell lines since these are two features of tumor ...
arxiv
Advanced Functional Materials, EarlyView.Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier +26 more
wiley +1 more source
Brain, Behavior, & Immunity - HealthImmuno-oncology, specifically immune checkpoint inhibitors (ICIs), has revolutionized cancer care with dramatic, long-term responses and increased survival, including patients with metastatic cancer to the brain.
Steven Brem
doaj
What is the role of CRP in glioblastoma?
Cancer Treatment and Research Communications, 2021 Background: Glioblastoma is the most common primary malignant brain tumor in adults. Previous studies have suggested that CRP (C-reactive protein) could serve as a biomarker candidate as well as a prognostic factor in glioblastoma patients, and we here ...
Karolina Förnvik +5 more
doaj
Learning a Generative Model of Cancer Metastasis [PDF]
arXiv, 2019 We introduce a Unified Disentanglement Network (UFDN) trained on The Cancer Genome Atlas (TCGA). We demonstrate that the UFDN learns a biologically relevant latent space of gene expression data by applying our network to two classification tasks of cancer status and cancer type.
arxiv
H2O2‐Generating Advanced Nanomaterials for Cancer Treatment
Advanced Functional Materials, EarlyView.H2O2‐generating nanoplatforms can exploit tumor redox imbalance for O2 and toxic reactive oxygen species generation, leading to hypoxia reversal, and apoptosis of cancer cells, respectively. This review highlights the mechanisms of these nanoplatforms, including exogenous H₂O₂ delivery, endogenous amplification, and metal peroxides, which leads to ...
Kiyan Musaie +8 more
wiley +1 more source
Genetics and epigenetics of glioblastoma: applications and overall incidence of IDH1 mutation
Frontiers in Oncology, 2016 Glioblastoma is the most fatal brain cancer found in humans. Patients suffering from glioblastoma have a dismal prognosis, with a median survival of 15 months. The tumor may develop rapidly de novo in older patients or through progression from anaplastic
Xuan eZong +5 more
doaj +1 more source
A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides
Advanced Healthcare Materials, EarlyView.Self‐assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare them to that of native extracellular matrix components, which are found to display a much wider range of structural attributes.
Alex Hartley +2 more
wiley +1 more source
eLifeEstablishing a zebrafish model of a deadly type of brain tumor highlights the role of the immune system in the early stages of the disease.
openaire +3 more sources
Advanced Healthcare Materials, EarlyView.This study investigates nanoscale temperatures generated by photoexcited gold nanostars and their correlation with microscale thermal damage at the cellular level. Using X‐ray absorption spectroscopy and confocal microscopy in 3D cancer spheroids, it assesses localized heating effects and examines tumor cell structure and integrity, offering insights ...
Rosalía López‐Méndez +11 more
wiley +1 more source