Results 11 to 20 of about 18,786 (126)

Evaluation of the Cytotoxic Effects of Ciprofloxacin on Human Glioblastoma A-172 Cell Line

Middle East Journal of Cancer, 2017
Background: Glioblastoma multiforme, the most common, aggressive malignant brain tumor which affects patients of all ages, is principally resistant to treatment. Ciprofloxacin is an antibiotic that belongs to the fluoroquinolones.
Ashkan Zandi, Taraneh Moini Zanjani, Seyed Ali Ziai, Yalda Khazaei Poul, Mostafa Haji Molla Hoseini   +4 more
doaj   +1 more source

The Synergistic Effects of the Combination of Ciprofloxacin and Temozolomide on Human Glioblastoma A-172 Cell Line

Middle East Journal of Cancer, 2017
Background: Combination therapy has generated remarkable motivation in the clinical setting since it boosts the therapeutic potential of anticancer drugs.
Ashkan Zandi, Taraneh Moini Zanjani, Seyed Ali Ziai, Yalda Khazaei Poul, Mostafa Haji Molla Hoseini   +4 more
doaj   +1 more source

Targeted intracellular delivery of resveratrol to glioblastoma cells using apolipoprotein E-containing reconstituted HDL as a nanovehicle. [PDF]

PLoS ONE, 2015
The objective of this study is to transport and deliver resveratrol to intracellular sites using apolipoprotein E3 (apoE3). Reconstituted high-density lipoprotein (rHDL) bearing resveratrol (rHDL/res) was prepared using phospholipids and the low-density ...
Sea H Kim, Birendra Babu Adhikari, Siobanth Cruz, Michael P Schramm, Joe A Vinson, Vasanthy Narayanaswami   +5 more
doaj   +1 more source

CK2 Inhibition and Antitumor Activity of 4,7-Dihydro-6-nitroazolo[1,5-a]pyrimidines

Molecules, 2022
Today, cancer is one of the most widespread and dangerous human diseases with a high mortality rate. Nevertheless, the search and application of new low-toxic and effective drugs, combined with the timely diagnosis of diseases, makes it possible to cure ...
Daniil N. Lyapustin, Svetlana K. Kotovskaya, Ilya I. Butorin, Evgeny N. Ulomsky, Vladimir L. Rusinov, Denis A. Babkov, Alexander A. Pokhlebin, Alexander A. Spasov, Vsevolod V. Melekhin, Maria D. Tokhtueva, Anna V. Shcheglova, Oleg G. Makeev   +11 more
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Synthesis of silver nanoparticles using Salvia officinalis extract: Structural characterization, cytotoxicity, antileishmanial and antimicrobial activity [PDF]

Nanomedicine Research Journal, 2020
Objective: This study aimed to investigate the cytotoxicity, antileishmanial and antibacterial potential of silver nanoparticles (AgNPs) synthesized by (Salvia officinalis L. (Sage)) extract.
Fatemeh Sharifi, Fariba Sharififar, Sara Soltanian, Mohsen Doostmohammadi, Neda Mohamadi   +4 more
doaj   +1 more source

Lichen Secondary Metabolites Inhibit the Wnt/β-Catenin Pathway in Glioblastoma Cells and Improve the Anticancer Effects of Temozolomide

Cells, 2022
Lichens are a source of secondary metabolites with significant pharmacological potential. Data regarding their possible application in glioblastoma (GBM) treatment are, however, scarce.
Aleksandra Majchrzak-Celińska, Robert Kleszcz, Elżbieta Studzińska-Sroka, Agnieszka Łukaszyk, Anna Szoszkiewicz, Ewelina Stelcer, Karol Jopek, Marcin Rucinski, Judyta Cielecka-Piontek, Violetta Krajka-Kuźniak   +9 more
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Lichen-Derived Compounds and Extracts as Biologically Active Substances with Anticancer and Neuroprotective Properties

Pharmaceuticals, 2021
Lichens are a source of chemical compounds with valuable biological properties, structurally predisposed to penetration into the central nervous system (CNS).
Elżbieta Studzińska-Sroka, Aleksandra Majchrzak-Celińska, Przemysław Zalewski, Dominik Szwajgier, Ewa Baranowska-Wójcik, Barbara Kaproń, Tomasz Plech, Marcin Żarowski, Judyta Cielecka-Piontek   +8 more
doaj   +1 more source

Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53

BMC Biotechnology, 2002
Background We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53.
Ohnishi Ken, Ohnishi Takeo, Takahashi Akihisa   +2 more
doaj   +1 more source

Cell growth inhibition and apoptotic effects of a specific anti-RTFscFv antibody on prostate cancer, but not glioblastoma, cells [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Background: Single chain antibody (scFv) has shown interesting results in cancer immunotargeting approaches, due to its advantages over monoclonal antibodies.
Foroogh Nejatollahi, Payam Bayat, Bahareh Moazen   +2 more
doaj   +1 more source

Cell type-specific Effect of miRZip-21 to Suppress miR-21 in Human Glioma Cell Lines [PDF]

Journal of Cell and Molecular Research, 2019
There are different subtypes of brain tumors, classified according to the origin of the abnormally proliferated glial cells. Glioblastoma multiforma (GBM) is the grade 4 of brain tumors, gliomas, with the least life expectancy.
Hamideh Monfared, Yavar Jahangard, Maryam Nikkhah, Seyed Javad Mirnajafi-Zade, Seyed Javad Mowla   +4 more
doaj   +1 more source