Results 21 to 30 of about 115,602,437 (109)

Identifying the role of Mer receptor tyrosine kinase in glioblastoma multiforme [PDF]

, 2012
GBM is one of the most aggressive human cancers. Primary GBM, which comprises more than 90% of biopsied or resected brain tumors, arises de novo without an antecedent history of low-grade disease.
Yuhua, Wang
core   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Synthesis of Silver Nanoparticles using Methanol Extract of Bunium Persicum and the Evaluation of its Cytotoxic, Antileishmanial, and Antimicrobial Activities

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: The unique properties of silver nanoparticles (Ag-NPs) produced using plant extract make them attractive for use in medical and industrial applications.
Fatemeh Sharifi, Neda MohamadI, Sara Soltanian, Mohsen Doostmohammadi   +3 more
doaj  

A Customisable Cell Line Model of Glioblastoma

, 2021
Glioblastoma is an extremely malignant brain tumour with one of the lowest survival rates of all cancers. Current treatments do very little to alter this prognosis. Research into new therapies and the biology of glioblastoma has made scarce progress over
Devlin Forsythe (11370840)
core   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

The molecular role of non-canonical Notch signaling via Deltex-1 in high grade glioma [PDF]

, 2011
Glioblastoma Multiforme is a WHO grade IV brain tumor with glial characteristics leading to more years of life lost than any other cancer. A better understanding of GBM biology and valid animal models are the two key elements to improved therapeutic ...
Huber, Roland Martin
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

Strategies of eradicating glioma cells : a multi-scale mathematical model with miR-451-AMPK-mTOR control [PDF]

, 2015
The cellular dispersion and therapeutic control of glioblastoma, the most aggressive type of primary brain cancer, depends critically on the migration patterns after surgery and intracellular responses of the individual cancer cells in response to ...
Gibin Powathil, Trucu Dumitru, Kang Hyunji, Kim Hyeongi, Chaplain Mark, Lawler Sean, Mark Chaplain, Gibin Powathil (687047), Powathil, Gibin, Hyeongi Kim, Trucu, Dumitru, Kim, Hyeongi, Dumitru Trucu, Sean Lawler (191146), Kim, Yangjin, Hyunji Kang, Hyeongi Kim (687050), Yangjin Kim, Lawler, Sean, Kim Yangjin, Sean Lawler, Kang, Hyunji, Hyunji Kang (687048), Trucu, Dumitru; id_orcid, Dumitru Trucu (687049), Mark Chaplain (249544), Powathil Gibin, Chaplain, Mark, Yangjin Kim (191134)   +28 more
core   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source