Results 1 to 10 of about 394,478 (362)
A toy model of fractal glioma development under RF electric field treatment [PDF]
A toy model for glioma treatment by a radio frequency electric field is suggested. This low-intensity, intermediate-frequency alternating electric field is known as the tumor-treating-field (TTF). In the framework of this model the efficiency of this TTF is estimated, and the interplay between the TTF and the migration-proliferation dichotomy of cancer
A. Chauviere+29 more
arxiv +3 more sources
Why one-size-fits-all vaso-modulatory interventions fail to control glioma invasion: in silico insights [PDF]
There is an ongoing debate on the therapeutic potential of vaso-modulatory interventions against glioma invasion. Prominent vasculature-targeting therapies involve functional tumour-associated blood vessel deterioration and normalisation. The former aims at tumour infarction and nutrient deprivation medi- ated by vascular targeting agents that induce ...
Alfonso, J. C. L.+5 more
arxiv +3 more sources
Residual Channel Attention Network for Brain Glioma Segmentation [PDF]
A glioma is a malignant brain tumor that seriously affects cognitive functions and lowers patients' life quality. Segmentation of brain glioma is challenging because of interclass ambiguities in tumor regions. Recently, deep learning approaches have achieved outstanding performance in the automatic segmentation of brain glioma.
arxiv +1 more source
ZDHHC15 promotes glioma malignancy and acts as a novel prognostic biomarker for patients with glioma
Background Glioma is the most common and aggressive tumor in the adult brain. Recent studies have indicated that Zinc finger DHHC-type palmitoyltransferases (ZDHHCs) play vital roles in regulating the progression of glioma.
Zhen-Yuan Liu+8 more
doaj +1 more source
Background PTPRZ1-MET fusion was reported to associate with glioma progression from low-grade to high-grade glioma, which was a target by a MET inhibitor vebreltinib.
Zhaoshi Bao+7 more
doaj +1 more source
Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma
Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure.
Ying Zhang+11 more
doaj +1 more source
Objective TERT is the most frequently mutated gene in adult glioblastomas (GBMs) defined by the 2021 World Health Organization classification system. The present study aims to explore differences in clinical characteristics and immune microenvironment ...
Feng Tang+6 more
doaj +1 more source
Selective Targeting to Glioma with Nucleic Acid Aptamers [PDF]
Malignant glioma is characterised by a rapid growth rate and high capacity for invasive infiltration to surrounding brain tissue; hence, diagnosis and treatment is difficult and patient survival is poor.
Alder, Jane Elizabeth+7 more
core +5 more sources