Results 121 to 130 of about 79,800 (306)

Nanoparticle‐integrated electrostimulation‐responsive biomaterials: Innovations in drug delivery and tissue repair in clinical regenerative medicine

Interdisciplinary Medicine, EarlyView.
Schematic representation of nanoparticle‐integrated electrostimulation‐responsive biomaterials for controlled drug delivery and tissue regeneration. Electroactive scaffolds including conductive polymers, electroresponsive hydrogels, and piezoelectric matrices are shown incorporating therapeutic nanoparticles (such as iron oxide, silver, and carbon ...
Peyman Halvaeikhanekahdani, Sajad Zandi, Qadeer Ahmad, Hadiseh Payravand   +3 more
wiley   +1 more source

Corrigendum: Lysophosphatidic Acid Receptor 1 Specifically Labels Seizure-Induced Hippocampal Reactive Neural Stem Cells and Regulates Their Division

Frontiers in Neuroscience, 2020
Roberto Valcárcel-Martín, Roberto Valcárcel-Martín, Soraya Martín-Suárez, Teresa Muro-García, Teresa Muro-García, Oier Pastor-Alonso, Oier Pastor-Alonso, Fernando Rodríguez de Fonseca, Guillermo Estivill-Torrús, Juan Manuel Encinas, Juan Manuel Encinas, Juan Manuel Encinas   +11 more
doaj   +1 more source

Licochalcone A attenuates NMDA-induced neurotoxicity

Animal Cells and Systems
This study investigates the effect of Licochalcone A (Lico-A), a flavonoid from licorice roots known for its anti-inflammatory, anti-cancer, and antioxidant properties, on NMDA-induced neurotoxicity in primary cultured rat hippocampal neurons.
Jae Soo Kim, Mi-Hye Kim, Myeung Ju Kim, Hee Jung Kim   +3 more
doaj   +1 more source

Therapeutic Potential of Photobiomodulation in Early Recovery After Experimental Spinal Cord Injury in Rats: Histological and Biomechanical Analysis

Journal of Biophotonics, EarlyView.
Spinal cord injuries (SCI) cause severe motor and sensory deficits, with limited treatment options. This study demonstrates that early application of photobiomodulation (PBM) can protect spinal cord tissue and accelerate functional recovery in a preclinical model, which integrates biomechanical analysis with histomorphological characteristics of the ...
Débora Campos Chaves Correia, Leonardo Borges de Lima, Mário Oliveira Lima, Luis Filipe Karatanasov Beloni, Raduan Hage, Emilia Angela Lo Schiavo Arisawa   +5 more
wiley   +1 more source

Prognostic Value of Parkinson's Disease Subtypes in the LABS‐PD Cohort: Functional Ability, Quality of Life and Mortality

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash, Shirley Eberly, David Oakes, David Grimes, Anthony E. Lang, Caroline Tanner, Tiago A. Mestre, Connie Marras   +7 more
wiley   +1 more source

Ataxia with oculomotor apraxia type 2: a clinical, pathologic, and genetic study [PDF]

, 2006
BACKGROUND: Ataxia with oculomotor apraxia type 2 (AOA2) is characterized by onset between age 10 and 22 years, cerebellar atrophy, peripheral neuropathy, oculomotor apraxia (OMA), and elevated serum alpha-fetoprotein (AFP) levels. Recessive mutations in
BANFI S, BARBIERI, FABRIZIO, CASALI C., CHESSA L, CRISCUOLO C, DE MICHELE, GIUSEPPE, DI GIANDOMENICO S, FILLA, ALESSANDRO, GALLOSTI L, GRIECO GS, MANCINI P, PIANE M, PIERELLI F, RIZZUTO N, SACCA', FRANCESCO, SANTORELLI FM   +15 more
core  

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Virchow-Robin spaces : an anatomic variant or a pathologic sign? [PDF]

, 2009
Virchow-Robin spaces surround blood vessels. Their walls are formed by prolongations of the pia mater and they have no communication with the subarachnoid space. VRS are often seen as well-delineated foci of cerebrospinal fluid signal on MR images.

core  

Pain-related behavior is associated with increased joint innervation, ipsilateral dorsal horn gliosis, and dorsal root ganglia activating transcription factor 3 expression in a rat ankle joint model of osteoarthritis

, 2020
Valerie Bourassa, Haley Deamond, Noosha Yousefpour, Mary‐Ann Fitzcharles, Alfredo Ribeiro‐da‐Silva   +4 more
openalex   +1 more source

Cerebrospinal Fluid Biomarkers of NLRP3 Pathway, Immune Dysregulation, and Neurodegeneration in Parkinson's Disease: A Meta‐Analysis

Movement Disorders, EarlyView.
Abstract Background The activation of the NOD‐, LRR‐ and pyrin domain‐containing protein 3 (NLRP3) inflammasome and associated immune dysregulation is one of the key pathological processes preceding and accompanying α‐synuclein pathology, neuronal damage, and cell death in Parkinson's disease (PD).
Alina‐Măriuca Marinescu, Venissa Machado, Gennaro Pagano, Nicoletta Milani Muelhardt, Thomas Kustermann, Eva Zsuzsanna Mracsko, Kathrin Brockmann, Nima Shariati, Judith Anzures‐Cabrera, Bastian Zinnhardt   +9 more
wiley   +1 more source