Results 41 to 50 of about 78,953 (285)
Molecules, 2021 Transient ischemia in brains causes neuronal damage, gliosis, and blood–brain barrier (BBB) breakdown, which is related to ischemia-induced brain dysfunction.
Tae-Kyeong Lee +10 more
doaj +1 more source
The Zebrafish as a Model for Ocular Translational Research: From Retinal Repair to Regeneration
CellsIn the last years, the zebrafish model has become a primary model system for vertebrate tissue regeneration, particularly for neurodegeneration and metabolic disease.
Bijorn Omar Balzamino +5 more
doaj +1 more source
The Response of Cerebral Cortex to Haemorrhagic Damage: Experimental Evidence from a Penetrating Injury Model [PDF]
, 2015 Understanding the response of the brain to haemorrhagic damage is important in haemorrhagic stroke and increasingly in the understanding the cerebral degeneration and dementia that follow head trauma and head-impact sports.
Johnstone, Daniel M. +4 more
core +1 more source
Experimental Biology and Medicine, 1962 ConclusionMorphologic and histochemical studies of glial reaction during Wallerian degeneration in the dorsal column of the spinal cord have shown that reactive gliosis is independent of alterations of the blood-spinal cord barrier. These data suggest that substances inducing gliosis may pre-exist in normal central nervous system tissue.
K A, OSTERBERG, L W, WATTENBERG
openaire +2 more sources
Elevated Hydrostatic Pressure Causes Retinal Degeneration Through Upregulating Lipocalin-2
Frontiers in Cell and Developmental Biology, 2021 Elevation of intraocular pressure is a major risk factor for glaucoma development, which causes the loss of retinal ganglion cells (RGCs). Lipocalin 2 (Lcn2) is upregulated in glaucomatous retinae; however, whether Lcn2 is directly involved in glaucoma ...
Azusa Yoneshige +7 more
doaj +1 more source
Inhomogeneous cortical synchronization and partial epileptic seizures [PDF]
, 2014 Objective: Interictal synchronization clusters have recently been described in several publications using diverse techniques, including neurophysiological recordings and fMRI, in patients suffering from epilepsy.
García de Sola, Rafael +3 more
core +1 more source
Brain Sciences, 2019 Microelectrode implants are an important tool in neuroscience research and in developing brain⁻machine interfaces. Data from rodents have consistently shown that astrocytes are recruited to the area surrounding implants, forming a glial scar that ...
Samuel A. Budoff +7 more
doaj +1 more source
Frontiers in Neuroscience, 2019 Metabolic syndrome and diabetes impact brain function and metabolism. While it is well established that rodents exposed to diets rich in saturated fat develop brain dysfunction, contrasting results abound in the literature, likely as result of exposure ...
Blanca Lizarbe +6 more
doaj +1 more source
Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification. [PDF]
, 2020 Primary familial brain calcification (PFBC) is a rare neurodegenerative disorder characterized by a combination of neurological, psychiatric, and cognitive decline associated with calcium deposition on brain imaging. To date, mutations in five genes have
A. Athanasiou-Fragkouli +86 more
core +8 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source