Results 31 to 40 of about 55,381 (288)

Chronic Histological Outcomes of Indirect Traumatic Optic Neuropathy in Adolescent Mice: Persistent Degeneration and Temporally Regulated Glial Responses

open access: yesCells, 2021
Injury to the optic nerve, termed, traumatic optic neuropathy (TON) is a known comorbidity of traumatic brain injury (TBI) and is now known to cause chronic and progressive retinal thinning up to 35 years after injury.
Shelby M. Hetzer   +3 more
doaj   +1 more source

Regulation of Gliosis in the Mouse Retina [PDF]

open access: yes, 2017
The glial cells of the retina aid in function and maintenance of the retina. The macroglia, Muller cells and the retinal astrocytes, become reactive following injury or disease in the retina, a response that is characterized by hypertrophy ...
Dharmarajan, Subramanian
core   +1 more source

Massive Retinal Gliosis Mistaken as a Malignant Intraocular Tumor in Phthisis Bulbi

open access: yesDiagnostics, 2022
Massive retinal gliosis (MRG) is a rare condition of non-neoplastic glial proliferation, which forms massive lesions that fill the eye. MRG is commonly associated with phthisis bulbi (a non-functional eye), congenital anomalies, or malformations. Herein,
Soyoung Im   +3 more
doaj   +1 more source

Opioids, gliosis and central immunomodulation [PDF]

open access: yesJournal of Anesthesia, 2018
Neuropathic pain is a common health problem that affects millions of people worldwide. Despite being studied extensively, the cellular and molecular events underlying the central immunomodulation and the pathophysiology of neuropathic pain is still controversial.
Kadhim, Salim   +2 more
openaire   +3 more sources

The Zebrafish as a Model for Ocular Translational Research: From Retinal Repair to Regeneration

open access: yesCells
In the last years, the zebrafish model has become a primary model system for vertebrate tissue regeneration, particularly for neurodegeneration and metabolic disease.
Bijorn Omar Balzamino   +5 more
doaj   +1 more source

Restless Legs Syndrome Shows Increased Silent Postmortem Cerebral Microvascular Disease With Gliosis

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Patients with restless legs syndrome (RLS) have increased silent microvascular disease by magnetic resonance imaging. However, there has been no previous autopsy confirmation of these magnetic resonance imaging findings. RLS is also frequently
Arthur S. Walters   +6 more
doaj   +1 more source

Populus tomentiglandulosa Extract Is Rich in Polyphenols and Protects Neurons, Astrocytes, and the Blood-Brain Barrier in Gerbil Striatum Following Ischemia-Reperfusion Injury

open access: yesMolecules, 2021
Transient ischemia in brains causes neuronal damage, gliosis, and blood–brain barrier (BBB) breakdown, which is related to ischemia-induced brain dysfunction.
Tae-Kyeong Lee   +10 more
doaj   +1 more source

Astrocytic Response to Acutely- and Chronically-Implanted Microelectrode Arrays in the Marmoset (Callithrix jacchus) Brain

open access: yesBrain Sciences, 2019
Microelectrode implants are an important tool in neuroscience research and in developing brain⁻machine interfaces. Data from rodents have consistently shown that astrocytes are recruited to the area surrounding implants, forming a glial scar that ...
Samuel A. Budoff   +7 more
doaj   +1 more source

Neurochemical Modifications in the Hippocampus, Cortex and Hypothalamus of Mice Exposed to Long-Term High-Fat Diet

open access: yesFrontiers in Neuroscience, 2019
Metabolic syndrome and diabetes impact brain function and metabolism. While it is well established that rodents exposed to diets rich in saturated fat develop brain dysfunction, contrasting results abound in the literature, likely as result of exposure ...
Blanca Lizarbe   +6 more
doaj   +1 more source

Elevated Hydrostatic Pressure Causes Retinal Degeneration Through Upregulating Lipocalin-2

open access: yesFrontiers in Cell and Developmental Biology, 2021
Elevation of intraocular pressure is a major risk factor for glaucoma development, which causes the loss of retinal ganglion cells (RGCs). Lipocalin 2 (Lcn2) is upregulated in glaucomatous retinae; however, whether Lcn2 is directly involved in glaucoma ...
Azusa Yoneshige   +7 more
doaj   +1 more source

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