Results 11 to 20 of about 78,953 (285)

Peripheral and central effects of NADPH oxidase inhibitor, mitoapocynin, in a rat model of diisopropylfluorophosphate (DFP) toxicity

open access: yesFrontiers in Cellular Neuroscience, 2023
Organophosphates (OP) are highly toxic chemical nerve agents that have been used in chemical warfare. Currently, there are no effective medical countermeasures (MCMs) that mitigate the chronic effects of OP exposure.
Christina Meyer   +8 more
doaj   +1 more source

CD8 T-cell Recruitment Into the Central Nervous System of Cuprizone-Fed Mice: Relevance to Modeling the Etiology of Multiple Sclerosis

open access: yesFrontiers in Cellular Neuroscience, 2020
Cuprizone (CPZ)-feeding in mice induces atrophy of peripheral immune organs (thymus and spleen) and suppresses T-cell levels, thereby limiting its use as a model for studying the effects of the immune system in demyelinating diseases such as Multiple ...
Mohammed S. M. Almuslehi   +6 more
doaj   +1 more source

S100B inhibitor pentamidine attenuates reactive gliosis and reduces neuronal loss in a mouse model of Alzheimer's disease [PDF]

open access: yes, 2015
Among the different signaling molecules released during reactive gliosis occurring in Alzheimer’s disease (AD), the astrocytederived S100B protein plays a key role in neuroinflammation, one of the hallmarks of the disease.
Capoccia, Elena   +6 more
core   +5 more sources

Neuroprotection by upregulation of the major histocompatibility complex class I (MHC I) in SOD1G93A mice

open access: yesFrontiers in Cellular Neuroscience, 2023
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that progressively affects motoneurons, causing muscle atrophy and evolving to death. Astrocytes inhibit the expression of MHC-I by neurons, contributing to a degenerative outcome.
Ana Laura M. R. Tomiyama   +4 more
doaj   +1 more source

The role of glial cells in neurodegenerative diseases. Part 1. Characteristics and physiological functions [PDF]

open access: yesFarmacja Polska, 2022
The nervous system is composed of two dominant types of cells – neurons and glial cells. They differ from each other both morphologically and physiologically.
Mateusz Maszczyk   +2 more
doaj   +1 more source

Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]

open access: yes, 2015
Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR   +6 more
core   +1 more source

Trends in Gliosis in Obesity, and the Role of Antioxidants as a Therapeutic Alternative

open access: yesAntioxidants, 2022
Obesity remains a global health problem. Chronic low-grade inflammation in this pathology has been related to comorbidities such as cognitive alterations that, in the long term, can lead to neurodegenerative diseases.
Cindy Bandala   +9 more
doaj   +1 more source

Immature Teratoma With Metastatic Gliosis [PDF]

open access: yesCureus, 2022
Immature teratomas are rare malignant tumors of the ovary. They are made of immature components of germ cell origin. The incidence of immature teratomas is highest in young adults aged 18 to 39. The prognosis heavily depends on the International Federation of Gynecology and Obstetrics (FIGO) staging system and is influenced by factors such as cell type,
Ahoussougbemey Mele, Ange   +3 more
openaire   +2 more sources

Molecular assessment of intermediate filamented protein as a detective marker of quails' histopathological brain lesions [PDF]

open access: yesIraqi Journal of Veterinary Sciences
The nervous system plays a crucial role in regulating most of the body's vital functions. Stress factor or infection may affect the Nervous System, which includes both the central and peripheral systems.
Hadeel Al-Sabaawy   +2 more
doaj   +1 more source

Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes [PDF]

open access: yes, 2016
Reactive gliosis involving activation and proliferation of astrocytes and microglia, is a widespread but largely complex and graded glial response to brain injury.
Barbeito, Osvaldo Luis   +8 more
core   +1 more source

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