Results 51 to 60 of about 58,440 (301)

Effect of cellular protein kinases blockade on the s100 retina expression in experimental diabetic retinopathy

open access: yesPatologìâ
The positive effect of cellular protein kinases blockade in diabetes and diabetic retinopathy (DR) justifies the need to clarify molecular mechanisms, among which the trigger regulatory role belongs to calcium-binding proteins S100.
K. O. Usenko   +3 more
doaj   +1 more source

A spatiotemporal study of gliosis in relation to depth electrode tracks in drug-resistant epilepsy [PDF]

open access: yes, 2014
Key questions remain regarding the processes governing gliogenesis following central nervous system injury that are critical to understanding both beneficial brain repair mechanisms and any long-term detrimental effects, including increased risk of ...
Liu, J.Y.W.   +3 more
core   +1 more source

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi   +6 more
wiley   +1 more source

Biocompatibility of Platinum Nanoparticles in Brain ex vivo Models in Physiological and Pathological Conditions

open access: yesFrontiers in Neuroscience, 2021
Platinum nanoparticles (PtNPs) have unique physico-chemical properties that led to their use in many branches of medicine. Recently, PtNPs gathered growing interest as delivery vectors for drugs, biosensors and as surface coating on chronically implanted
Maurizio Gulino   +8 more
doaj   +1 more source

Zwitterionic Polymer Coating Enabled Chronic Dopamine Sensing and Electrophysiology Recording in Free‐Moving Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
Application of a zwitterionic poly(sulfobetaine methacrylate) (PSB) coating to microelectrode arrays and Ag/AgCl reference electrodes effectively inhibits biofouling and structural degradation. This strategy successfully enables simultaneous, long‐term electrophysiological recording and dopamine sensing in freely behaving mice, facilitating ...
Bingchen Wu   +5 more
wiley   +1 more source

Inhibitory Effects of Trifluoperazine on Peripheral Proinflammatory Cytokine Expression and Hypothalamic Microglia Activation in Obese Mice Induced by Chronic Feeding With High-Fat-Diet

open access: yesFrontiers in Cellular Neuroscience, 2021
Microglia and astrocytes are the glial cells of the central nervous system (CNS) to support neurodevelopment and neuronal function. Yet, their activation in association with CNS inflammation is involved in the initiation and progression of neurological ...
Hui-Ting Huang   +5 more
doaj   +1 more source

Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic

open access: yesAdvanced Robotics Research, EarlyView.
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang   +5 more
wiley   +1 more source

A Retrospective Analysis of Temporal Lobe Gliosis after Middle Fossa Resection of Small Vestibular Schwannomas

open access: yesBrain Sciences
Introduction: The middle cranial fossa (MCF) approach is a well-established procedure in surgery of the internal auditory canal, as well as with the retrosigmoid and translabyrinthine approaches. It is commonly used in the hearing-preserving microsurgery
Matthias Scheich   +6 more
doaj   +1 more source

Spatiotemporal patterns of gliosis and neuroinflammation in presenilin 1/2 conditional double knockout mice

open access: yesFrontiers in Aging Neuroscience, 2022
Increasing evidence indicates that neuroinflammation contributes to and exacerbates the pathogenesis of Alzheimer’s disease (AD). Neuroinflammation is thought to be primarily driven by glial cells (microglia and astrocytes) and escalates with ...
Wenjun Peng   +8 more
doaj   +1 more source

An Atypical Form of Gliosis Spinalis [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1894
n ...
openaire   +2 more sources

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