Results 61 to 70 of about 78,953 (285)

Inhibitory Effects of Trifluoperazine on Peripheral Proinflammatory Cytokine Expression and Hypothalamic Microglia Activation in Obese Mice Induced by Chronic Feeding With High-Fat-Diet

open access: yesFrontiers in Cellular Neuroscience, 2021
Microglia and astrocytes are the glial cells of the central nervous system (CNS) to support neurodevelopment and neuronal function. Yet, their activation in association with CNS inflammation is involved in the initiation and progression of neurological ...
Hui-Ting Huang   +5 more
doaj   +1 more source

One-hundred years (and counting) of blast-associated traumatic brain injury [PDF]

open access: yes, 2018
Blast-associated traumatic brain injury (TBI) has become one of the signature issues of modern warfare and is increasingly a concern in the civilian population due to a rise in terrorist attacks.
Fullerton, Josephine L.   +2 more
core   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Spatiotemporal patterns of gliosis and neuroinflammation in presenilin 1/2 conditional double knockout mice

open access: yesFrontiers in Aging Neuroscience, 2022
Increasing evidence indicates that neuroinflammation contributes to and exacerbates the pathogenesis of Alzheimer’s disease (AD). Neuroinflammation is thought to be primarily driven by glial cells (microglia and astrocytes) and escalates with ...
Wenjun Peng   +8 more
doaj   +1 more source

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

open access: yesAdvanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar   +4 more
wiley   +1 more source

Post-Traumatic Dancing Epilepsy

open access: yesPediatric Neurology Briefs, 2009
Researchers at Thomas Jefferson University Hospital, Philadelphia, PA, report a case of “dancing epilepsy” in a 39-year-old, right-handed man who developed refractory complex partial seizures following head trauma at 15 years of age.
J Gordon Millichap
doaj   +1 more source

A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs

open access: yesFrontiers in Cell and Developmental Biology, 2021
Müller glia (MG) are the predominant glia in the neural retina and become reactive after injury or in disease. microRNAs (miRNAs) are translational repressors that regulate a variety of processes during development and are required for MG function ...
Seoyoung Kang   +5 more
doaj   +1 more source

A Combination of Two Human Monoclonal Antibodies Limits Fetal Damage by Zika Virus in Macaques [PDF]

open access: yes, 2020
Human infection by Zika virus (ZIKV) during pregnancy can lead to vertical transmission and fetal aberrations, including microcephaly. Prophylactic administration of antibodies can diminish or prevent ZIKV infection in animal models, but whether passive ...
Agudelo, Marianna   +25 more
core   +2 more sources

Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus [PDF]

open access: yes, 2019
The association of WW domain-containing oxidoreductase WWOX gene loss of function with central nervous system (CNS) related pathologies is well documented.
Abba, Martín Carlos   +11 more
core   +2 more sources

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