Results 51 to 60 of about 64,779 (321)
Boundedness and Global Nonexistence for a Nonlinear Convective Parabolic-System
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Ames, K.A., Straughan, B.
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In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
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A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
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On the uniform boundedness of the solutions of systems of reaction-diffusion equations
We consider a system of reaction-diffusion equations for which the uniform boundedness of the solutions can not be derived by existing methods. The system may represent, in particular, an epidemic model describing the spread of an infection disease ...
L. Melkemi, Ahmed Mokrane, A. Youkana
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Global boundedness of a class of multilinear Fourier integral operators
We establish the global regularity of multilinear Fourier integral operators that are associated to nonlinear wave equations on products of $L^p$ spaces by proving endpoint boundedness on suitable product spaces containing combinations of the local ...
Salvador Rodríguez-López +2 more
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Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
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Global boundedness of a higher-dimensional chemotaxis system on alopecia areata
<abstract><p>This paper mainly focuses on the dynamics behavior of a three-component chemotaxis system on alopecia areata</p> <p><disp-formula> <label/> <tex-math id="FE1"> \begin{document}$ \begin{equation*} \left\{ \begin{array}{lll} u_t = \Delta{u}-\chi_1\nabla\cdot(u\nabla{w})+w-\mu_1u^2, &x\in ...
Wenjie Zhang, Lu Xu, Qiao Xin
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The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
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Sub-logistic source can prevent blow-up in the 2D minimal Keller-Segel chemotaxis system
It is well-known that the Neumann initial-boundary value problem for the minimal-chemotaxis-logistic system in a 2D bounded smooth domain has no blow-up for any choice of parameters. Here, for a large class of kinetic terms including sub-logistic sources,
Xiang, Tian
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Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
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